Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds

Plant Biotechnology Journal

Volumn 11, Issue 9, 2013, Pages 1034-1043

  He, Xu ^a   Pierce, Owen ^a   Haselhorst, Thomas ^b   von Itzstein, Mark ^b   Kolarich, Daniel ^c,f   Packer, Nicolle H ^c   Gloster, Tracey M ^a,g   Vocadlo, David J ^a   Qian, Yi ^d   Brooks, Doug ^e   Kermode, Allison R ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b GRIFFITH UNIVERSITY   (Australia)

^c MACQUARIE UNIVERSITY   (Australia)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^f MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

^g UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

Arabidopsis cgl mutant; Human L iduronidase; Mannose 6 phosphate recognition marker; Mucopolysaccharidosis I; N glycosylation

Indexed keywords

ARABIDOPSIS; CRICETULUS GRISEUS; MAMMALIA;

LEVO IDURONIDASE; MANNOSE; MANNOSE 6 PHOSPHATE; MANNOSE PHOSPHATE; MANNOSE-6-PHOSPHATE; POLYSACCHARIDE; RECOMBINANT PROTEIN;

ARABIDOPSIS; ARABIDOPSIS CGL MUTANT; ARTICLE; CHEMISTRY; ENZYMOLOGY; GENETICS; GLYCOSYLATION; HUMAN; HUMAN Α-L-IDURONIDASE; HURLER SYNDROME; KINETICS; MANNOSE-6-PHOSPHATE RECOGNITION MARKER; METABOLISM; MUTATION; N-GLYCOSYLATION; PHOSPHORYLATION; PLANT SEED; TRANSGENE; TRANSGENIC PLANT;

ARABIDOPSIS CGL MUTANT; HUMAN Α-L-IDURONIDASE; MANNOSE-6-PHOSPHATE RECOGNITION MARKER; MUCOPOLYSACCHARIDOSIS I; N-GLYCOSYLATION;

ARABIDOPSIS; GLYCOSYLATION; HUMANS; IDURONIDASE; KINETICS; MANNOSE; MANNOSEPHOSPHATES; MUCOPOLYSACCHARIDOSIS I; MUTATION; PHOSPHORYLATION; PLANTS, GENETICALLY MODIFIED; POLYSACCHARIDES; RECOMBINANT PROTEINS; SEEDS; TRANSGENES;

EID: 84888136369     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/pbi.12096     Document Type: Article

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