Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system

Plant Biotechnology Journal

Volumn 5, Issue 5, 2007, Pages 579-590

  Shaaltiel, Yoseph ^a   Bartfeld, Daniel ^a   Hashmueli, Sharon ^a   Baum, Gideon ^a   Brill Almon, Einat ^a   Galili, Gad ^b   Dym, Orly ^b   Boldin Adamsky, Swetlana A ^b   Silman, Israel ^b   Sussman, Joel L ^b   Futerman, Anthony H ^b   Aviezer, David ^a  

^a Protalix Biotherapeutics   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Cell culture; Gaucher's disease; Glucocerebrosidase; Mannose; Plant

Indexed keywords

GLUCOSYLCERAMIDASE; MANNOSE; POLYSACCHARIDE; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; CARROT; CELL CULTURE; CHEMISTRY; CHO CELL; CRICETULUS; CYTOLOGY; DRUG SCREENING; ENZYMOLOGY; FEMALE; GAUCHER DISEASE; GENETICS; HAMSTER; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; MACROPHAGE; MALE; METABOLISM; METHODOLOGY; MOUSE; WESTERN BLOTTING; X RAY CRYSTALLOGRAPHY;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; CRYSTALLOGRAPHY, X-RAY; DAUCUS CAROTA; DRUG EVALUATION, PRECLINICAL; FEMALE; GAUCHER DISEASE; GLUCOSYLCERAMIDASE; HUMANS; MACROPHAGES; MALE; MANNOSE; MICE; MICE, INBRED ICR; POLYSACCHARIDES; RECOMBINANT PROTEINS;

CRICETULUS GRISEUS; DAUCUS CAROTA; MAMMALIA; MUS;

EID: 34547586616     PISSN: 14677644     EISSN: 14677652     Source Type: Journal    
DOI: 10.1111/j.1467-7652.2007.00263.x     Document Type: Article

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