Influence of an ER-retention signal on the N-glycosylation of recombinant human α-l-iduronidase generated in seeds of Arabidopsis

Plant Molecular Biology

Volumn 79, Issue 1-2, 2012, Pages 157-169

  He, Xu ^a   Haselhorst, Thomas ^b   von Itzstein, Mark ^b   Kolarich, Daniel ^c,d   Packer, Nicolle H ^c   Kermode, Allison R ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b GRIFFITH UNIVERSITY   (Australia)

^c MACQUARIE UNIVERSITY   (Australia)

^d MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES   (Germany)

Author keywords

Arabidopsis cgl mutant; Complex N glycans; ER retention; Human l iduronidase; Mucopolysaccharidosis (MPS) I; N glycosylation

Indexed keywords

LEVO IDURONIDASE; MANNOSE; POLYSACCHARIDE; RECOMBINANT PROTEIN; SIGNAL PEPTIDE;

AMINO ACID SEQUENCE; ARABIDOPSIS; ARTICLE; CELL COMPARTMENTALIZATION; CELL FRACTIONATION; CELL VACUOLE; CHEMISTRY; CYTOLOGY; ENDOPLASMIC RETICULUM; GENETICS; GLYCOSYLATION; HUMAN; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; PLANT SEED; STRUCTURE ACTIVITY RELATION; TRANSGENIC PLANT; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ARABIDOPSIS; BLOTTING, WESTERN; CELL COMPARTMENTATION; ENDOPLASMIC RETICULUM; GLYCOSYLATION; HUMANS; IDURONIDASE; MANNOSE; MOLECULAR SEQUENCE DATA; PLANTS, GENETICALLY MODIFIED; POLYSACCHARIDES; PROTEIN SORTING SIGNALS; RECOMBINANT PROTEINS; SEEDS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBCELLULAR FRACTIONS; VACUOLES;

ARABIDOPSIS; ARABIDOPSIS THALIANA; PHASEOLUS VULGARIS;

EID: 84863416061     PISSN: 01674412     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11103-012-9902-5     Document Type: Article

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