Effects of accelerated senescence on learning and memory, locomotion and anxiety-like behavior in APP/PS1 mouse model of Alzheimer's disease

Journal of the Neurological Sciences

Volumn 335, Issue 1-2, 2013, Pages 145-154

  Lok, Kenghoe ^a   Zhao, Hong ^a   Zhang, Can ^a   He, Na ^a   Shen, Hanlin ^a   Wang, Zejian ^a   Zhao, Wenjuan ^a   Yin, Ming ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Anxiety; APP PS1; Learning memory; Locomotor; Senescence

Indexed keywords

AMYLOID BETA PROTEIN; BETA GALACTOSIDASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR CHANGE; COGNITION; CONTROLLED STUDY; DEMENTIA; DISEASE SEVERITY; IMMUNOHISTOCHEMISTRY; LEARNING; LOCOMOTION; MEMORY DISORDER; MOTOR PERFORMANCE; MOUSE; NONHUMAN; OPEN FIELD TEST; PHENOTYPE; PRIORITY JOURNAL; SENESCENCE; SPATIAL MEMORY; TRANSGENIC MOUSE; WORKING MEMORY;

AD; ALZHEIMER'S DISEASE; AMYLOID BETA; AMYLOID PRECURSOR PROTEIN; ANXIETY; APP; APP/PS1; AΒ; CONDITIONED STIMULUS; CS; LEARNING-MEMORY; LOCOMOTOR; NEUROFIBRILLARY TANGLES; NFTS; PRESENILIN 1; PRESENILIN 2; PS1; PS2; SAMP8; SENESCENCE; SENESCENCE ACCELERATED MOUSE PRONE 8; TBS; TRIS-BUFFERED SALINE; UCS; UNCONDITIONED STIMULUS;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANXIETY; DISEASE MODELS, ANIMAL; ESCAPE REACTION; EXPLORATORY BEHAVIOR; GAIT DISORDERS, NEUROLOGIC; GENOTYPE; HUMANS; LEARNING DISORDERS; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PRESENILIN-1;

EID: 84888135522     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2013.09.018     Document Type: Article

References (42)

1. D.L. Price, R.G. Struble, P.J. Whitehouse, C.A. Kitt, L.C. Cork, and L.C. Walker Alzheimer's disease: a multisystem disorder Res Publ Assoc Res Nerv Ment Dis 64 1986 209 214
2. S. Mirochnic, S. Wolf, M. Staufenbiel, and G. Kempermann Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease Hippocampus 19 2009 1008 1018
3. A. Levey, J. Lah, F. Goldstein, K. Steenland, and D. Bliwise Mild cognitive impairment: an opportunity to identify patients at high risk for progression to Alzheimer's disease Clin Ther 28 2006 991 1001
4. J. Haller, and M.R. Kruk Normal and abnormal aggression: human disorders and novel laboratory models Neurosci Biobehav Rev 30 2006 292 303
5. A. Gruart, J.C. López-Ramos, M.D. Muñoz, and J.M. Delgado-García Aged wild-type and APP, PS1, and APP + PS1 mice present similar deficits in associative learning and synaptic plasticity independent of amyloid load Neurobiol Dis 30 2008 439 450
6. L. Holcomb, M.N. Gordon, E. McGowan, X. Yu, S. Benkovic, and P. Jantzen Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes Nat Med 4 1998 97 100
7. T.L. Spires, and B.T. Hyman Transgenic models of Alzheimer's disease: learning from animals NeuroRx 2 2005 423 437
8. S.A. Ferguson, S. Sarkar, and L.C. Schmued Longitudinal behavioral changes in the APP/PS1 transgenic Alzheimer's disease model Behav Brain Res 242 2013 125 134
9. H. Wang, J. He, R. Zhang, S. Zhu, J. Wang, and L. Kong Sensorimotor gating and memory deficits in an APP/PS1 double transgenic mouse model of Alzheimer's disease Behav Brain Res 233 2012 237 243
10. P. Yan, A.W. Bero, J.R. Cirrito, Q. Xiao, X. Hu, and Y. Wang Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice J Neurosci 29 2009 10706 10714
11. R. Lalonde, H.D. Kim, and K. Fukuchi Exploratory activity, anxiety, and motor coordination in bigenic APPswe + PS1/DeltaE9 mice Neurosci Lett 369 2004 156 161
12. A. Sood, J. Warren Beach, S.J. Webster, A.V. Terry, and J.J. Buccafusco The effects of JWB1-84-1 on memory-related task performance by amyloid Abeta transgenic mice and by young and aged monkeys Neuropharmacology 53 2007 588 600
13. G.W. Arendash, D.L. King, M.N. Gordon, D. Morgan, J.M. Hatcher, and C.E. Hope Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes Brain Res 891 2001 42 53
14. J.L. Jankowsky, D.J. Fadale, J. Anderson, G.M. Xu, V. Gonzales, and N.A. Jenkins Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase Hum Mol Genet 13 2004 159 170
15. M. Hosokawa, R. Kasai, K. Higuchi, S. Takeshita, K. Shimizu, and H. Hamamoto Grading score system: a method for evaluation of the degree of senescence in senescence accelerated mouse (SAM) Mech Ageing Dev 26 1984 91 102
16. T. Kawamata, I. Akiguchi, H. Yagi, M. Irino, H. Sugiyama, and H. Akiyama Neuropathological studies on strains of senescence-accelerated mice (SAM) with age-related deficits in learning and memory Exp Gerontol 32 1997 161 169
17. T. Takeda, T. Matsushita, M. Kurozumi, K. Takemura, K. Higuchi, and M. Hosokawa Pathobiology of the senescence-accelerated mouse (SAM) Exp Gerontol 32 1997 117 127
18. H. Yagi, S. Katoh, I. Akiguchi, and T. Takeda Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal model of disturbances in recent memory Brain Res 474 1988 86 93
19. J.E. Morley, V.B. Kumar, A.E. Bernardo, S.A. Farr, K. Uezu, and N. Tumosa Beta-amyloid precursor polypeptide in SAMP8 mice affects learning and memory Peptides 21 2000 1761 1767
20. P.L. Pugh, J.C. Richardson, S.T. Bate, N. Upton, and D. Sunter Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease Behav Brain Res 178 2007 18 28
21. S. Pietropaolo, P. Delage, F. Lebreton, W.E. Crusio, and Y.H. Cho Early development of social deficits in APP and APP-PS1 mice Neurobiol Aging 33 2012 1002.e17 1002.e27
22. R. Lalonde, H.D. Kim, and K. Fukuchi Exploratory activity, anxiety, and motor coordination in bigenic APPswe + PS1/ΔE9 mice Neurosci Lett 369 2004 156 161
23. M. Miyamoto Characteristics of age-related behavioral changes in senescence-accelerated mouse SAMP8 and SAMP10 Exp Gerontol 32 1997 139 148
24. D.M. Walsh, and D.J. Selkoe Deciphering the molecular basis of memory failure in Alzheimer's disease Neuron 44 2004 181 193
25. S. Karantzoulis, and J.E. Galvin Distinguishing Alzheimer's disease from other major forms of dementia Expert Rev Neurother 11 2011 1579 1591
26. G.B. Frisoni, L. Rozzini, A. Gozzetti, G. Binetti, O. Zanetti, and A. Bianchetti Behavioral syndromes in Alzheimer's disease: description and correlates Dement Geriatr Cogn Disord 10 1999 130 138
27. C. Ballard, A.N.N. Boyle, C. Bowler, and J. Lindesay Anxiety disorders in dementia sufferers Int J Geriatr Psychiatry 11 1996 987 990
28. A. Walton, J.L. Scheib, S. McLean, Z. Zhang, and R. Grondin Motor memory preservation in aged monkeys mirrors that of aged humans on a similar task Neurobiol Aging 29 2008 1556 1562
29. S.A. Farr, W.A. Banks, K. Uezu, A. Sano, F.S. Gaskin, and J.E. Morley Antibody to β-amyloid protein increases acetylcholine in the hippocampus of 12 month SAMP8 male mice Life Sci 73 2003 555 562
30. K.A.C. Glazner, G.L. Odero, E. Anema, A. Motnenko, J. Schapansky, and D. Grossman Strain specific differences in memory and neuropathology in a mouse model of Alzheimer's disease Life Sci 86 2010 942 950
31. V. Haroutunian, Y. Zhou, G. Elder, C. Li, and R.A. Lazzarini Age-dependent spatial memory deficits in transgenic mice expressing the human mid-sized neurofilament gene: I Mol Brain Res 42 1996 62 70
32. R. Lalonde, H.D. Kim, J.A. Maxwell, and K. Fukuchi Exploratory activity and spatial learning in 12-month-old APP(695)SWE/co + PS1/DeltaE9 mice with amyloid plaques Neurosci Lett 390 2005 87 92
33. N.M. Timmer, L. van Dijk, CEEMv der Zee, A. Kiliaan, R.M.W. de Waal, and M.M. Verbeek Enoxaparin treatment administered at both early and late stages of amyloid β deposition improves cognition of APPswe/PS1dE9 mice with differential effects on brain Aβ levels Neurobiol Dis 40 2010 340 347
34. F. Dellu, W. Mayo, M. Vallee, M. Le Moal, and H. Simon Facilitation of cognitive performance in aged rats by past experience depends on the type of information processing involved: a combined cross-sectional and longitudinal study Neurobiol Learn Mem 67 1997 121 128
35. P.L. Pugh, M.P. Vidgeon-Hart, T. Ashmeade, A.A. Culbert, Z. Seymour, and M.J. Perren Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes J Neuroinflammation 4 2007 8
36. D.R. Howlett, J.C. Richardson, A. Austin, A.A. Parsons, S.T. Bate, and D.C. Davies Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes Brain Res 1017 2004 130 136
37. Y. Yu, J. He, Y. Zhang, H. Luo, S. Zhu, and Y. Yang Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model Hippocampus 19 2009 1247 1253
38. T. Nishiyama NM, Y. Zhang, and H. Saito Comprehensive studies on learning disability in senescence accelerated mouse prone 8 Excerpta Medica International Congress 1st International Conference: Excerpta Medica 1994 385 388
39. M. Miyamoto, Y. Kiyota, N. Yamazaki, A. Nagaoka, T. Matsuo, and Y. Nagawa Age-related changes in learning and memory in the senescence-accelerated mouse (SAM) Physiol Behav 38 1986 399 406
40. M. Padurariu, A. Ciobica, L. Hritcu, B. Stoica, W. Bild, and C. Stefanescu Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer's disease Neurosci Lett 469 2010 6 10
41. A. Tanaka, Y. Watanabe, H. Kato, and T. Araki Immunohistochemical changes related to ageing in the mouse hippocampus and subventricular zone Mech Ageing Dev 128 2007 303 310
42. J.R. Manns, R.O. Hopkins, J.M. Reed, E.G. Kitchener, and L.R. Squire Recognition memory and the human hippocampus Neuron 37 2003 171 180