Isoxanthohumol modulates angiogenesis and inflammation via vascular endothelial growth factor receptor, tumor necrosis factor alpha and nuclear factor kappa B pathways

BioFactors

Volumn 39, Issue 6, 2013, Pages 608-622

  Negrão, Rita ^a   Duarte, Delfim ^a   Costa, Raquel ^a   Soares, Raquel ^a  

^a University of Porto   (Portugal)

Author keywords

Akt; Angiogenesis; Erk; HASMC; HUVEC; Isoxanthohumol; NF B; Retinal angiogenesis; TNF ; VEGFR2

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOXANTHOHUMOL; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD VESSEL PARAMETERS; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETINA NEOVASCULARIZATION; SMOOTH MUSCLE FIBER; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

AKT; ANGIOGENESIS; ERK; HASMC; HUVEC; ISOXANTHOHUMOL; NFΚB; RETINAL ANGIOGENESIS; TNF-Α; VEGFR2;

ANGIOGENESIS MODULATING AGENTS; ANGIOPOIETINS; ANIMALS; CELL MOVEMENT; CELLS, CULTURED; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION MEDIATORS; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, TIE-2; RETINAL VESSELS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; XANTHONES;

EID: 84888135448     PISSN: 09516433     EISSN: 18728081     Source Type: Journal    
DOI: 10.1002/biof.1122     Document Type: Article

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