메뉴 건너뛰기




Volumn 36, Issue 2, 2013, Pages 616-623

Personalized medicine in Alzheimer's disease and depression

Author keywords

Alzheimer's disease; Depression; Epigenetics; Personalized medicine

Indexed keywords

ALPHA 1 ANTITRYPSIN; AMYLOID PRECURSOR PROTEIN; CITALOPRAM; DONEPEZIL; FLUORINE 18; HYDROCORTISONE; MEMANTINE; MYELOPEROXIDASE; NEUROTROPHIC FACTOR; PROLACTIN; PROTEIN S 100; RECEPTOR; RESISTIN; TAU PROTEIN; THREONINE;

EID: 84888132481     PISSN: 15517144     EISSN: 15592030     Source Type: Journal    
DOI: 10.1016/j.cct.2013.06.012     Document Type: Review
Times cited : (15)

References (82)
  • 3
    • 84870469320 scopus 로고    scopus 로고
    • American Psychiatric Association, [Text Revision (DSM-IV-TR®)]
    • American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders 2000, [Text Revision (DSM-IV-TR®)]. 4th ed.
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 5
    • 84888132988 scopus 로고    scopus 로고
    • International Classification of Diseases-10 Chapter 5. Classification of mental and behavioural disorders. Clinical descriptions and diagnostic guidelines. Geneva: World Health Organization.
    • International Classification of Diseases-10 Chapter 5. Classification of mental and behavioural disorders. Clinical descriptions and diagnostic guidelines. Geneva: World Health Organization.
  • 6
    • 84884807808 scopus 로고    scopus 로고
    • Organization, variation and expression of the human genome as a foundation of genomic and personalized medicine
    • Academic Press, London UK, H.W. Willard, G.S. Ginsburg (Eds.)
    • Willard H.W. Organization, variation and expression of the human genome as a foundation of genomic and personalized medicine. Genomic and personalized medicine 2009, 4-21. Academic Press, London UK. H.W. Willard, G.S. Ginsburg (Eds.).
    • (2009) Genomic and personalized medicine , pp. 4-21
    • Willard, H.W.1
  • 7
    • 84861940981 scopus 로고    scopus 로고
    • Pharmacogenomics and personalized medicine in neuropsychiatry
    • McMahon F.J., Insel T.R. Pharmacogenomics and personalized medicine in neuropsychiatry. Neuron 2012, 74(5):773-776.
    • (2012) Neuron , vol.74 , Issue.5 , pp. 773-776
    • McMahon, F.J.1    Insel, T.R.2
  • 8
    • 84870064521 scopus 로고    scopus 로고
    • Why has it taken so long for biological psychiatry to develop clinical tests and what to do about it?
    • Kapur S., Phillips A.G., Insel T.R. Why has it taken so long for biological psychiatry to develop clinical tests and what to do about it?. Mol Psychiatry 2012, 17(12):1174-1179.
    • (2012) Mol Psychiatry , vol.17 , Issue.12 , pp. 1174-1179
    • Kapur, S.1    Phillips, A.G.2    Insel, T.R.3
  • 9
    • 84888131890 scopus 로고    scopus 로고
    • National Institute of Mental Health, website:, [last accessed 6/11/2013]
    • National Institute of Mental Health website:, [last accessed 6/11/2013]. http://www.nimh.nih.gov/research-priorities/rdoc/nimh-research-domain-criteria-rdoc.shtml.
  • 11
    • 84858225391 scopus 로고    scopus 로고
    • 2012 Alzheimer's disease facts and figures
    • Alzheimer's Association
    • Alzheimer's Association 2012 Alzheimer's disease facts and figures. Alzheimers Dement 2012, 8(2):131-168.
    • (2012) Alzheimers Dement , vol.8 , Issue.2 , pp. 131-168
  • 13
    • 84865176138 scopus 로고    scopus 로고
    • Locus-specific mutation databases for neurodegenerative brain diseases
    • Cruts M., Theuns J., Van Broeckhoven C. Locus-specific mutation databases for neurodegenerative brain diseases. Hum Mutat 2012, 33:1340-1344.
    • (2012) Hum Mutat , vol.33 , pp. 1340-1344
    • Cruts, M.1    Theuns, J.2    Van Broeckhoven, C.3
  • 14
    • 0027936838 scopus 로고
    • Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease
    • [PubMed: 8083686]
    • Roses A.D. Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease. J Neuropathol Exp Neurol 1994, 53(5):429-437. [PubMed: 8083686].
    • (1994) J Neuropathol Exp Neurol , vol.53 , Issue.5 , pp. 429-437
    • Roses, A.D.1
  • 15
    • 84873722367 scopus 로고    scopus 로고
    • Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
    • Feb [PMID: 23296339]
    • Liu C.C., Kanekiyo T., Xu H., Bu G. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat Rev Neurol Feb 2013, 9(2):106-118. [PMID: 23296339].
    • (2013) Nat Rev Neurol , vol.9 , Issue.2 , pp. 106-118
    • Liu, C.C.1    Kanekiyo, T.2    Xu, H.3    Bu, G.4
  • 16
    • 34447322271 scopus 로고    scopus 로고
    • Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria
    • Aug [Review]
    • Dubois B., Feldman H.H., Jacova C., Dekosky S.T., Barberger-Gateau P., Cummings J., et al. Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurol Aug 2007, 6(8):734-746. [Review].
    • (2007) Lancet Neurol , vol.6 , Issue.8 , pp. 734-746
    • Dubois, B.1    Feldman, H.H.2    Jacova, C.3    Dekosky, S.T.4    Barberger-Gateau, P.5    Cummings, J.6
  • 17
    • 79956142378 scopus 로고    scopus 로고
    • The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • McKhann G.M., Knopman D.S., Chertkow H., Hyman B.T., Jack C.R., Kawas C.H., et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011, 7(3):263-269.
    • (2011) Alzheimers Dement , vol.7 , Issue.3 , pp. 263-269
    • McKhann, G.M.1    Knopman, D.S.2    Chertkow, H.3    Hyman, B.T.4    Jack, C.R.5    Kawas, C.H.6
  • 18
    • 79956076567 scopus 로고    scopus 로고
    • Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • May
    • Jack C.R., Albert M.S., Knopman D.S., McKhann G.M., Sperling R.A., Carrillo M.C., et al. Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement May 2011, 7(3):257-262.
    • (2011) Alzheimers Dement , vol.7 , Issue.3 , pp. 257-262
    • Jack, C.R.1    Albert, M.S.2    Knopman, D.S.3    McKhann, G.M.4    Sperling, R.A.5    Carrillo, M.C.6
  • 19
    • 0032989712 scopus 로고    scopus 로고
    • Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease
    • Mar
    • Price J.L., Morris J.C. Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease. Ann Neurol Mar 1999, 45(3):358-368.
    • (1999) Ann Neurol , vol.45 , Issue.3 , pp. 358-368
    • Price, J.L.1    Morris, J.C.2
  • 20
    • 84875760414 scopus 로고    scopus 로고
    • Florbetapir F 18 for brain imaging of β-amyloid plaques
    • Mar
    • Romano M., Buratti E. Florbetapir F 18 for brain imaging of β-amyloid plaques. Drugs Today (Barc) Mar 2013, 49(3):181-193.
    • (2013) Drugs Today (Barc) , vol.49 , Issue.3 , pp. 181-193
    • Romano, M.1    Buratti, E.2
  • 21
    • 0033613129 scopus 로고    scopus 로고
    • Cellular mechanisms of beta-amyloid production and secretion
    • Sep 28, [Review]
    • Sinha S., Lieberburg I. Cellular mechanisms of beta-amyloid production and secretion. Proc Natl Acad Sci U S A Sep 28 1999, 96(20):11049-11053. [Review].
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.20 , pp. 11049-11053
    • Sinha, S.1    Lieberburg, I.2
  • 22
    • 84885028399 scopus 로고    scopus 로고
    • Biomarkers in Alzheimer's disease: a review
    • [(Mci)]
    • Chintamaneni M., Bhaskar M. Biomarkers in Alzheimer's disease: a review. ISRN, Pharmacology 2012, 984786. [(Mci)].
    • (2012) ISRN, Pharmacology , pp. 984786
    • Chintamaneni, M.1    Bhaskar, M.2
  • 23
    • 65249159879 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarker signature in Alzheimer's Disease Neuroimaging Initiative subjects. Alzheimer's Disease Neuroimaging Initiative
    • Apr
    • Shaw L.M., Vanderstichele H., Knapik-Czajka M., Clark C.M., Aisen P.S., Petersen R.C., et al. Cerebrospinal fluid biomarker signature in Alzheimer's Disease Neuroimaging Initiative subjects. Alzheimer's Disease Neuroimaging Initiative. Ann Neurol Apr 2009, 65(4):403-413.
    • (2009) Ann Neurol , vol.65 , Issue.4 , pp. 403-413
    • Shaw, L.M.1    Vanderstichele, H.2    Knapik-Czajka, M.3    Clark, C.M.4    Aisen, P.S.5    Petersen, R.C.6
  • 24
    • 84856002055 scopus 로고    scopus 로고
    • National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
    • Hyman B.T., Phelps C.H., Beach T.G., Bigio E.H., Cairns N.J., Carrillo M.C., et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimers Dement 2012, 8(1):1-13.
    • (2012) Alzheimers Dement , vol.8 , Issue.1 , pp. 1-13
    • Hyman, B.T.1    Phelps, C.H.2    Beach, T.G.3    Bigio, E.H.4    Cairns, N.J.5    Carrillo, M.C.6
  • 25
    • 79960764322 scopus 로고    scopus 로고
    • The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers
    • Mattsson N., Andreasson U., Persson S., Arai H., Batish S.D., Bernardini S., et al. The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimers Dement 2011, 7(4):386-395.e6.
    • (2011) Alzheimers Dement , vol.7 , Issue.4
    • Mattsson, N.1    Andreasson, U.2    Persson, S.3    Arai, H.4    Batish, S.D.5    Bernardini, S.6
  • 26
    • 84865507286 scopus 로고    scopus 로고
    • Proficiency testing programs for Alzheimer's disease cerebrospinal fluid biomarkers
    • Mattsson N., Andreasson U., Carrillo M.C., Persson S., Shaw L.M., Zegers I., et al. Proficiency testing programs for Alzheimer's disease cerebrospinal fluid biomarkers. Biomark Med 2012, 6(4):401-407.
    • (2012) Biomark Med , vol.6 , Issue.4 , pp. 401-407
    • Mattsson, N.1    Andreasson, U.2    Carrillo, M.C.3    Persson, S.4    Shaw, L.M.5    Zegers, I.6
  • 27
    • 84865481319 scopus 로고    scopus 로고
    • Upcoming candidate cerebrospinal fluid biomarkers of Alzheimer's disease
    • Fagan A.M., Perrin R.J. Upcoming candidate cerebrospinal fluid biomarkers of Alzheimer's disease. Biomark Med 2012, 6(4):455-476.
    • (2012) Biomark Med , vol.6 , Issue.4 , pp. 455-476
    • Fagan, A.M.1    Perrin, R.J.2
  • 28
  • 29
    • 84865512129 scopus 로고    scopus 로고
    • Plasma biomarkers for Alzheimer's disease: much needed but tough to find
    • Bazenet C., Lovestone S. Plasma biomarkers for Alzheimer's disease: much needed but tough to find. Biomark Med 2012, 6(4):441-454.
    • (2012) Biomark Med , vol.6 , Issue.4 , pp. 441-454
    • Bazenet, C.1    Lovestone, S.2
  • 30
    • 84879083786 scopus 로고    scopus 로고
    • Fluid biomarkers in Alzheimer's disease - current concepts
    • Jun 21
    • Rosén C., Hansson O., Blennow K., Zetterberg H. Fluid biomarkers in Alzheimer's disease - current concepts. Mol Neurodegener Jun 21 2013, 8(20).
    • (2013) Mol Neurodegener , vol.8 , Issue.20
    • Rosén, C.1    Hansson, O.2    Blennow, K.3    Zetterberg, H.4
  • 31
    • 84869126018 scopus 로고    scopus 로고
    • Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study
    • Dec
    • Reiman E.M., Quiroz Y.T., Fleisher A.S., Chen K., Velez-Pardo C., Jimenez-Del-Rio M., et al. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study. Lancet Neurol Dec 2012, 11(12):1048-1056.
    • (2012) Lancet Neurol , vol.11 , Issue.12 , pp. 1048-1056
    • Reiman, E.M.1    Quiroz, Y.T.2    Fleisher, A.S.3    Chen, K.4    Velez-Pardo, C.5    Jimenez-Del-Rio, M.6
  • 32
    • 84867339786 scopus 로고    scopus 로고
    • Blood-based protein biomarkers for diagnosis of Alzheimer disease. Alzheimer's Disease Neuroimaging Initiative; Australian Imaging Biomarker and Lifestyle Research Group
    • Oct
    • Doecke J.D., Laws S.M., Faux N.G., Wilson W., Burnham S.C., Lam C.P., et al. Blood-based protein biomarkers for diagnosis of Alzheimer disease. Alzheimer's Disease Neuroimaging Initiative; Australian Imaging Biomarker and Lifestyle Research Group. Arch Neurol Oct 2012, 69(10):1318-1325.
    • (2012) Arch Neurol , vol.69 , Issue.10 , pp. 1318-1325
    • Doecke, J.D.1    Laws, S.M.2    Faux, N.G.3    Wilson, W.4    Burnham, S.C.5    Lam, C.P.6
  • 33
    • 60849104123 scopus 로고    scopus 로고
    • Alzheimer disease: time to improve its diagnosis and treatment
    • Salloway S., Correia S. Alzheimer disease: time to improve its diagnosis and treatment. Cleve Clin J Med 2009, 76:49-58.
    • (2009) Cleve Clin J Med , vol.76 , pp. 49-58
    • Salloway, S.1    Correia, S.2
  • 34
    • 84862806815 scopus 로고    scopus 로고
    • Pharmacotherapies for Alzheimer's disease: beyond cholinesterase inhibitors
    • Tayeb H.O., Yang H.D., Price B.H., Tarazi F.I. Pharmacotherapies for Alzheimer's disease: beyond cholinesterase inhibitors. Pharmacol Ther 2012, 134(1):8-25.
    • (2012) Pharmacol Ther , vol.134 , Issue.1 , pp. 8-25
    • Tayeb, H.O.1    Yang, H.D.2    Price, B.H.3    Tarazi, F.I.4
  • 35
    • 0033536163 scopus 로고    scopus 로고
    • Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
    • Schenk D., Barbour R., Dunn W., Gordon G., Grajeda H., Guido T., et al. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 1999, 400(6740):173-177.
    • (1999) Nature , vol.400 , Issue.6740 , pp. 173-177
    • Schenk, D.1    Barbour, R.2    Dunn, W.3    Gordon, G.4    Grajeda, H.5    Guido, T.6
  • 36
    • 10744230547 scopus 로고    scopus 로고
    • Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization
    • Jul 8
    • Orgogozo J.M., Gilman S., Dartigues J.F., Laurent B., Puel M., Kirby L.C., et al. Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology Jul 8 2003, 61(1):46-54.
    • (2003) Neurology , vol.61 , Issue.1 , pp. 46-54
    • Orgogozo, J.M.1    Gilman, S.2    Dartigues, J.F.3    Laurent, B.4    Puel, M.5    Kirby, L.C.6
  • 37
    • 84877254025 scopus 로고    scopus 로고
    • Passive anti-amyloid immunotherapy in Alzheimer's disease: what are the most promising targets?
    • May 11
    • Moreth J., Mavoungou C., Schindowski K. Passive anti-amyloid immunotherapy in Alzheimer's disease: what are the most promising targets?. Immunol Ageing May 11 2013, 10(1):18.
    • (2013) Immunol Ageing , vol.10 , Issue.1 , pp. 18
    • Moreth, J.1    Mavoungou, C.2    Schindowski, K.3
  • 38
    • 84861418086 scopus 로고    scopus 로고
    • US government sets out Alzheimer's plan
    • May 22
    • Wadman M. US government sets out Alzheimer's plan. Nature May 22 2012, 485(7399):426-427.
    • (2012) Nature , vol.485 , Issue.7399 , pp. 426-427
    • Wadman, M.1
  • 39
    • 79959370222 scopus 로고    scopus 로고
    • Disease-modifying treatments for Alzheimer's disease
    • Jul
    • Galimberti D., Scarpini E. Disease-modifying treatments for Alzheimer's disease. Ther Adv Neurol Disord Jul 2011, 4(4):203-216.
    • (2011) Ther Adv Neurol Disord , vol.4 , Issue.4 , pp. 203-216
    • Galimberti, D.1    Scarpini, E.2
  • 40
    • 84875514732 scopus 로고    scopus 로고
    • Regulatory innovation and drug development for early-stage Alzheimer's disease
    • Mar 28
    • Kozauer N., Katz R. Regulatory innovation and drug development for early-stage Alzheimer's disease. N Engl J Med Mar 28 2013, 368(13):1169-1171.
    • (2013) N Engl J Med , vol.368 , Issue.13 , pp. 1169-1171
    • Kozauer, N.1    Katz, R.2
  • 41
    • 84888127523 scopus 로고    scopus 로고
    • [last accessed 6/12/2013]
    • [last accessed 6/12/2013]. http://www.alz.org/documents_custom/final_adni_genome_sequencing_news_release.pdf.
  • 43
    • 84858221983 scopus 로고    scopus 로고
    • The neurobiology of depression
    • [Review]
    • Palazidou E. The neurobiology of depression. Br Med Bull 2012, 101:127-145. [Review].
    • (2012) Br Med Bull , vol.101 , pp. 127-145
    • Palazidou, E.1
  • 45
    • 0017151345 scopus 로고
    • Neuroendocrine regulation in depression. II. Discrimination of depressed from nondepressed patients
    • Carroll B.J., Curtis G.C., Mendels J. Neuroendocrine regulation in depression. II. Discrimination of depressed from nondepressed patients. Arch Gen Psychiatry 1976, 33(9):1051-1058.
    • (1976) Arch Gen Psychiatry , vol.33 , Issue.9 , pp. 1051-1058
    • Carroll, B.J.1    Curtis, G.C.2    Mendels, J.3
  • 46
    • 0018971571 scopus 로고
    • Diagnosis of endogenous depression. Comparison of clinical, research and neuroendocrine criteria
    • Carroll B.J., Feinberg M., Greden J.F., Haskett R.F., James N.M., Steiner M., et al. Diagnosis of endogenous depression. Comparison of clinical, research and neuroendocrine criteria. J Affect Disord 1980, 2(3):177-194.
    • (1980) J Affect Disord , vol.2 , Issue.3 , pp. 177-194
    • Carroll, B.J.1    Feinberg, M.2    Greden, J.F.3    Haskett, R.F.4    James, N.M.5    Steiner, M.6
  • 47
    • 0019435794 scopus 로고
    • A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utility
    • Carroll B.J., Feinberg M., Greden J.F., Tarika J., Albala A.A., Haskett R.F., et al. A specific laboratory test for the diagnosis of melancholia. Standardization, validation, and clinical utility. Arch Gen Psychiatry 1981, 38(1):15-22.
    • (1981) Arch Gen Psychiatry , vol.38 , Issue.1 , pp. 15-22
    • Carroll, B.J.1    Feinberg, M.2    Greden, J.F.3    Tarika, J.4    Albala, A.A.5    Haskett, R.F.6
  • 48
    • 0023232461 scopus 로고
    • The dexamethasone suppression test: an overview of its current status in psychiatry
    • American Psychiatric Association
    • American Psychiatric Association The dexamethasone suppression test: an overview of its current status in psychiatry. Am J Psychiatry 1987, 144:1253-1262.
    • (1987) Am J Psychiatry , vol.144 , pp. 1253-1262
  • 49
    • 84875445534 scopus 로고    scopus 로고
    • Assessment of a multi-assay, serum-based biological diagnostic test for major depressive disorder: a pilot and replication study
    • December 13
    • Papakostas G.I., Shelton R.C., Kinrys G., Henry M.E., Bakow B.R., Lipkin S.H., et al. Assessment of a multi-assay, serum-based biological diagnostic test for major depressive disorder: a pilot and replication study. Mol Psychiatry December 13 2011, 1-8.
    • (2011) Mol Psychiatry , pp. 1-8
    • Papakostas, G.I.1    Shelton, R.C.2    Kinrys, G.3    Henry, M.E.4    Bakow, B.R.5    Lipkin, S.H.6
  • 50
    • 84888127981 scopus 로고    scopus 로고
    • Diagnostics, Ridge. "MDDScore™ Product Brief": 110. "Improving the diagnosis of major depressive disorder: a new multi-analyte biomarker panel".
    • Diagnostics, Ridge. "MDDScore™ Product Brief": 110. "Improving the diagnosis of major depressive disorder: a new multi-analyte biomarker panel".
  • 51
    • 0034853189 scopus 로고    scopus 로고
    • The PHQ-9: validity of a brief depression severity measure
    • Sep
    • Kroenke K., Spitzer R.L., Williams J.B. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med Sep 2001, 16(9):606-613.
    • (2001) J Gen Intern Med , vol.16 , Issue.9 , pp. 606-613
    • Kroenke, K.1    Spitzer, R.L.2    Williams, J.B.3
  • 52
    • 0033943902 scopus 로고    scopus 로고
    • Problems with currently available antidepressants
    • Gumnick J.F., Nemeroff C.B. Problems with currently available antidepressants. J Clin Psychiatry 2000, 51-4:5-15.
    • (2000) J Clin Psychiatry , pp. 5-15
    • Gumnick, J.F.1    Nemeroff, C.B.2
  • 53
    • 0034564477 scopus 로고    scopus 로고
    • Safety and tolerability considerations: tricyclic antidepressants vs. selective serotonin reuptake inhibitors
    • [Review]
    • Peretti S., Judge R., Hindmarch I. Safety and tolerability considerations: tricyclic antidepressants vs. selective serotonin reuptake inhibitors. Acta Psychiatr Scand Suppl 2000, 403:17-25. [Review].
    • (2000) Acta Psychiatr Scand Suppl , vol.403 , pp. 17-25
    • Peretti, S.1    Judge, R.2    Hindmarch, I.3
  • 54
    • 67650783189 scopus 로고    scopus 로고
    • Pharmacogenetics of selective serotonin reuptake inhibitors and associated adverse drug reactions
    • J 29, [Review]
    • Thomas K.L., Ellingrod V.L. Pharmacogenetics of selective serotonin reuptake inhibitors and associated adverse drug reactions. Pharmacotherapy Jul 29 2009, 7:822-831. [Review].
    • (2009) Pharmacotherapy , vol.7 , pp. 822-831
    • Thomas, K.L.1    Ellingrod, V.L.2
  • 55
    • 30044433660 scopus 로고    scopus 로고
    • Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice
    • Jan
    • Trivedi M.H., Rush A.J., Wisniewski S.R., Nierenberg A.A., Warden D., Ritz L., et al. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice. Am J Psychiatry Jan 2006, 163(1):28-40.
    • (2006) Am J Psychiatry , vol.163 , Issue.1 , pp. 28-40
    • Trivedi, M.H.1    Rush, A.J.2    Wisniewski, S.R.3    Nierenberg, A.A.4    Warden, D.5    Ritz, L.6
  • 56
    • 34347374871 scopus 로고    scopus 로고
    • Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression
    • Hu X.-Z., Rush A.J., Charney D., Wilson A.F., Sorant A.J., Papanicolaou G.J., et al. Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. Arch Gen Psychiatry 2007, 64(7):783-792.
    • (2007) Arch Gen Psychiatry , vol.64 , Issue.7 , pp. 783-792
    • Hu, X.-Z.1    Rush, A.J.2    Charney, D.3    Wilson, A.F.4    Sorant, A.J.5    Papanicolaou, G.J.6
  • 58
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • Nov 29
    • Lesch K.P., Bengel D., Heils A., Sabol S.Z., Greenberg B.D., Petri S., et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science Nov 29 1996, 274(5292):1527-1531.
    • (1996) Science , vol.274 , Issue.5292 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3    Sabol, S.Z.4    Greenberg, B.D.5    Petri, S.6
  • 59
    • 0037270399 scopus 로고    scopus 로고
    • The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit
    • Jan
    • Lovejoy E.A., Scott A.C., Fiskerstrand C.E., Bubb V.J., Quinn J.P. The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unit. Eur J Neurosci Jan 2003, 17(2):417-420.
    • (2003) Eur J Neurosci , vol.17 , Issue.2 , pp. 417-420
    • Lovejoy, E.A.1    Scott, A.C.2    Fiskerstrand, C.E.3    Bubb, V.J.4    Quinn, J.P.5
  • 60
    • 84857236103 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy
    • Apr [Review]
    • Porcelli S., Fabbri C., Serretti A. Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy. Eur Neuropsychopharmacol Apr 2012, 22(4):239-258. [Review].
    • (2012) Eur Neuropsychopharmacol , vol.22 , Issue.4 , pp. 239-258
    • Porcelli, S.1    Fabbri, C.2    Serretti, A.3
  • 61
    • 84877785575 scopus 로고    scopus 로고
    • Response to citalopram is not associated with SLC6A4 genotype in African-Americans and Caucasians with major depression
    • May 30
    • Poland R.E., Lesser I.M., Wan Y.J., Gertsik L., Yao J., Raffel L.J., et al. Response to citalopram is not associated with SLC6A4 genotype in African-Americans and Caucasians with major depression. Life Sci May 30 2013, 92(20-21):967-970.
    • (2013) Life Sci , vol.92 , Issue.20-21 , pp. 967-970
    • Poland, R.E.1    Lesser, I.M.2    Wan, Y.J.3    Gertsik, L.4    Yao, J.5    Raffel, L.J.6
  • 62
    • 34548084895 scopus 로고    scopus 로고
    • Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort
    • Aug
    • Paddock S., Laje G., Charney D., Rush A.J., Wilson A.F., Sorant A.J., et al. Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort. Am J Psychiatry Aug 2007, 164(8):1181-1188.
    • (2007) Am J Psychiatry , vol.164 , Issue.8 , pp. 1181-1188
    • Paddock, S.1    Laje, G.2    Charney, D.3    Rush, A.J.4    Wilson, A.F.5    Sorant, A.J.6
  • 63
    • 44349188699 scopus 로고    scopus 로고
    • The FKBP5-gene in depression and treatment response-an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D)
    • Jun 15
    • Lekman M., Laje G., Charney D., Rush A.J., Wilson A.F., Sorant A.J., et al. The FKBP5-gene in depression and treatment response-an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D). Cohort Biol Psychiatry Jun 15 2008, 63(12):1103-1110.
    • (2008) Cohort Biol Psychiatry , vol.63 , Issue.12 , pp. 1103-1110
    • Lekman, M.1    Laje, G.2    Charney, D.3    Rush, A.J.4    Wilson, A.F.5    Sorant, A.J.6
  • 64
    • 50249189084 scopus 로고    scopus 로고
    • Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study
    • Nov
    • Perlis R.H., Moorjani P., Fagerness J., Purcell S., Trivedi M.H., Fava M., et al. Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D study. Neuropsychopharmacology Nov 2008, 33(12):2810-2819.
    • (2008) Neuropsychopharmacology , vol.33 , Issue.12 , pp. 2810-2819
    • Perlis, R.H.1    Moorjani, P.2    Fagerness, J.3    Purcell, S.4    Trivedi, M.H.5    Fava, M.6
  • 65
    • 70350787070 scopus 로고    scopus 로고
    • Pharmacogenetics studies in STAR*D: strengths, limitations, and results
    • Nov
    • Laje G., Perlis R.H., Rush A.J., McMahon F.J. Pharmacogenetics studies in STAR*D: strengths, limitations, and results. Psychiatr Serv Nov 2009, 60(11):1446-1457.
    • (2009) Psychiatr Serv , vol.60 , Issue.11 , pp. 1446-1457
    • Laje, G.1    Perlis, R.H.2    Rush, A.J.3    McMahon, F.J.4
  • 67
    • 48549093980 scopus 로고    scopus 로고
    • Clinically relevant pharmacokinetic drug interactions with second-generation antidepressants: an update
    • Jul, [Review]
    • Spina E., Santoro V., D'Arrigo C. Clinically relevant pharmacokinetic drug interactions with second-generation antidepressants: an update. Clin Ther Jul 2008, 30(7):1206-1227. [Review].
    • (2008) Clin Ther , vol.30 , Issue.7 , pp. 1206-1227
    • Spina, E.1    Santoro, V.2    D'Arrigo, C.3
  • 68
    • 77951250023 scopus 로고    scopus 로고
    • Psychiatric pharmacogenomic testing in clinical practice
    • [Review]
    • Mrazek D.A. Psychiatric pharmacogenomic testing in clinical practice. Dialogues Clin Neurosci 2010, 12(1):69-76. [Review].
    • (2010) Dialogues Clin Neurosci , vol.12 , Issue.1 , pp. 69-76
    • Mrazek, D.A.1
  • 69
    • 62449286261 scopus 로고    scopus 로고
    • DNA microarray technology in the clinical environment: the AmpliChip CYP450 Test for CYP2D6 and CYP2C19 genotyping
    • de Leon J., Susce M.T., Johnson M., Hardin M., Maw L., Shao A., et al. DNA microarray technology in the clinical environment: the AmpliChip CYP450 Test for CYP2D6 and CYP2C19 genotyping. CNS Spectr 2009, 14(1):19-34.
    • (2009) CNS Spectr , vol.14 , Issue.1 , pp. 19-34
    • de Leon, J.1    Susce, M.T.2    Johnson, M.3    Hardin, M.4    Maw, L.5    Shao, A.6
  • 70
    • 57649139354 scopus 로고    scopus 로고
    • Pharmacogenomics: the promise of personalized medicine for CNS disorders
    • de Leon J. Pharmacogenomics: the promise of personalized medicine for CNS disorders. Neuropsychopharmacology 2009, 34(1):159-172.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.1 , pp. 159-172
    • de Leon, J.1
  • 71
    • 84857143959 scopus 로고    scopus 로고
    • Basic concepts of epigenetics: impact of environmental signals on gene expression
    • Mazzio E.A., Karam F.A.S. Basic concepts of epigenetics: impact of environmental signals on gene expression. Epigenetics 2012, 7(2):119-130.
    • (2012) Epigenetics , vol.7 , Issue.2 , pp. 119-130
    • Mazzio, E.A.1    Karam, F.A.S.2
  • 72
    • 84875334550 scopus 로고    scopus 로고
    • Genomic and epigenomic insights into nutrition and brain disorders
    • Mar 15
    • Dauncey M.J. Genomic and epigenomic insights into nutrition and brain disorders. Nutrients Mar 15 2013, 5(3):887-914.
    • (2013) Nutrients , vol.5 , Issue.3 , pp. 887-914
    • Dauncey, M.J.1
  • 73
    • 79961221664 scopus 로고    scopus 로고
    • The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life
    • Aug, [Review]
    • Szyf M. The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life. Epigenetics Aug 2011, 6(8):971-978. [Review].
    • (2011) Epigenetics , vol.6 , Issue.8 , pp. 971-978
    • Szyf, M.1
  • 74
    • 84871445347 scopus 로고    scopus 로고
    • The circadian clock: a framework linking metabolism, epigenetics and neuronal function
    • Jan
    • Masri S., Sassone-Corsi P. The circadian clock: a framework linking metabolism, epigenetics and neuronal function. Nat Rev Neurosci Jan 2013, 14(1):69-75.
    • (2013) Nat Rev Neurosci , vol.14 , Issue.1 , pp. 69-75
    • Masri, S.1    Sassone-Corsi, P.2
  • 75
    • 84882788493 scopus 로고    scopus 로고
    • Sex, stress, and epigenetics: regulation of behavior in animal models of mood disorders
    • Jan 21
    • Hodes G.E. Sex, stress, and epigenetics: regulation of behavior in animal models of mood disorders. Biol Sex Differ Jan 21 2013, 4(1):1.
    • (2013) Biol Sex Differ , vol.4 , Issue.1 , pp. 1
    • Hodes, G.E.1
  • 76
    • 84875235105 scopus 로고    scopus 로고
    • Bridging the transgenerational gap with epigenetic memory
    • Mar
    • Lim J.P., Brunet A. Bridging the transgenerational gap with epigenetic memory. Trends Genet Mar 2013, 29(3):176-186.
    • (2013) Trends Genet , vol.29 , Issue.3 , pp. 176-186
    • Lim, J.P.1    Brunet, A.2
  • 78
    • 60749105468 scopus 로고    scopus 로고
    • Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
    • Mar
    • McGowan P.O., Sasaki A., D'Alessio A.C., Dymov S., Labonté B., Szyf M., et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci Mar 2009, 12(3):342-348.
    • (2009) Nat Neurosci , vol.12 , Issue.3 , pp. 342-348
    • McGowan, P.O.1    Sasaki, A.2    D'Alessio, A.C.3    Dymov, S.4    Labonté, B.5    Szyf, M.6
  • 79
    • 79955943143 scopus 로고    scopus 로고
    • Pharmacoepigenetics: a new approach to predicting individual drug responses and targeting new drugs
    • [Review]
    • Baer-Dubowska W., Majchrzak-Celińska A., Cichocki M. Pharmacoepigenetics: a new approach to predicting individual drug responses and targeting new drugs. Pharmacol Rep 2011, 63(2):293-304. [Review].
    • (2011) Pharmacol Rep , vol.63 , Issue.2 , pp. 293-304
    • Baer-Dubowska, W.1    Majchrzak-Celińska, A.2    Cichocki, M.3
  • 80
    • 62649101737 scopus 로고    scopus 로고
    • Pharmacoepigenetics: its role in interindividual differences in drug response
    • Apr, [Review]
    • Gomez A., Ingelman-Sundberg M. Pharmacoepigenetics: its role in interindividual differences in drug response. Clin Pharmacol Ther Apr 2009, 85(4):426-430. [Review].
    • (2009) Clin Pharmacol Ther , vol.85 , Issue.4 , pp. 426-430
    • Gomez, A.1    Ingelman-Sundberg, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.