-
1
-
-
84861361690
-
Mechanisms of Sec61/SecY-mediated protein translocation across membranes
-
Park E, Rapoport TA (2012) Mechanisms of Sec61/SecY-mediated protein translocation across membranes. Annu Rev Biophys 41:21-40
-
(2012)
Annu Rev Biophys
, vol.41
, pp. 21-40
-
-
Park, E.1
Rapoport, T.A.2
-
2
-
-
33748300566
-
The plug domain of yeast Sec61p is important for efficient protein translocation, but is not essential for cell viability
-
Junne T, Schwede T, Goder V, Spiess M (2006) The plug domain of yeast Sec61p is important for efficient protein translocation, but is not essential for cell viability. Mol Biol Cell 17(9-4063-4068
-
(2006)
Mol Biol Cell
, vol.17
, Issue.9
, pp. 4063-4068
-
-
Junne, T.1
Schwede, T.2
Goder, V.3
Spiess, M.4
-
3
-
-
33847698213
-
Deregulation of the SecYEG translocation channel upon removal of the plug domain
-
Maillard AP, Lalani S, Silva F, Belin D, Duong F (2007) Deregulation of the SecYEG translocation channel upon removal of the plug domain. J Biol Chem 282(2- 1281-1287
-
(2007)
J Biol Chem
, vol.282
, Issue.2
, pp. 1281-1287
-
-
Maillard, A.P.1
Lalani, S.2
Silva, F.3
Belin, D.4
Duong, F.5
-
4
-
-
79955901001
-
Preserving the membrane barrier for small molecules during bacterial protein translocation
-
Park E, Rapoport TA (2011) Preserving the membrane barrier for small molecules during bacterial protein translocation. Nature 473(7346-239-242
-
(2011)
Nature
, vol.473
, Issue.7346
, pp. 239-242
-
-
Park, E.1
Rapoport, T.A.2
-
5
-
-
13444262028
-
Recognition of transmembrane helices by the endoplasmic reticulum translocon
-
Hessa T, et al. (2005) Recognition of transmembrane helices by the endoplasmic reticulum translocon. Nature 433(7024-377-381
-
(2005)
Nature
, vol.433
, Issue.7024
, pp. 377-381
-
-
Hessa, T.1
-
6
-
-
37249037182
-
Molecular code for transmembrane-helix recognition by the Sec61 translocon
-
Hessa T, et al. (2007) Molecular code for transmembrane-helix recognition by the Sec61 translocon. Nature 450(7172-1026-1030
-
(2007)
Nature
, vol.450
, Issue.7172
, pp. 1026-1030
-
-
Hessa, T.1
-
7
-
-
60849083215
-
Analysis of transmembrane helix integration in the endoplasmic reticulum in S. Cerevisiae
-
Hessa T, Reithinger JH, von Heijne G, Kim H (2009) Analysis of transmembrane helix integration in the endoplasmic reticulum in S. cerevisiae. J Mol Biol 386(5-1222-1228
-
(2009)
J Mol Biol
, vol.386
, Issue.5
, pp. 1222-1228
-
-
Hessa, T.1
Reithinger, J.H.2
Von Heijne, G.3
Kim, H.4
-
8
-
-
57349168025
-
Molecular code for protein insertion in the endoplasmic reticulum membrane is similar for N(in)-C(out) and N(out)-C(in) transmembrane helices
-
Lundin C, Kim H, Nilsson I, White SH, von Heijne G (2008) Molecular code for protein insertion in the endoplasmic reticulum membrane is similar for N(in)-C(out) and N(out)-C(in) transmembrane helices. Proc Natl Acad Sci USA 105(41-15702-15707
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.41
, pp. 15702-15707
-
-
Lundin, C.1
Kim, H.2
Nilsson, I.3
White, S.H.4
Von Heijne, G.5
-
9
-
-
37349063087
-
Features of transmembrane segments that promote the lateral release from the translocase into the lipid phase
-
Xie K, et al. (2007) Features of transmembrane segments that promote the lateral release from the translocase into the lipid phase. Biochemistry 46(51-15153-15161
-
(2007)
Biochemistry
, vol.46
, Issue.51
, pp. 15153-15161
-
-
Xie, K.1
-
10
-
-
82355173188
-
Hydrophobicity scales: A thermodynamic looking glass into lipid-protein interactions
-
MacCallum JL, Tieleman DP (2011) Hydrophobicity scales: A thermodynamic looking glass into lipid-protein interactions. Trends Biochem Sci 36(12-653-662
-
(2011)
Trends Biochem Sci
, vol.36
, Issue.12
, pp. 653-662
-
-
Maccallum, J.L.1
Tieleman, D.P.2
-
11
-
-
84873675862
-
Reconciling the roles of kinetic and thermodynamic factors in membrane-protein insertion
-
Gumbart JC, Teo I, Roux B, Schulten K (2013) Reconciling the roles of kinetic and thermodynamic factors in membrane-protein insertion. J Am Chem Soc 135(6- 2291-2297
-
(2013)
J Am Chem Soc
, vol.135
, Issue.6
, pp. 2291-2297
-
-
Gumbart, J.C.1
Teo, I.2
Roux, B.3
Schulten, K.4
-
12
-
-
84869090494
-
Membrane protein TM segments are retained at the translocon during integration until the nascent chain cues FRET-detected release into bulk lipid
-
Hou B, Lin P-J, Johnson AE (2012) Membrane protein TM segments are retained at the translocon during integration until the nascent chain cues FRET-detected release into bulk lipid. Mol Cell 48(3-398-408
-
(2012)
Mol Cell
, vol.48
, Issue.3
, pp. 398-408
-
-
Hou, B.1
Lin, P.-J.2
Johnson, A.E.3
-
13
-
-
0141992130
-
Cotranslational protein integration into the ER membrane is mediated by the binding of nascent chains to translocon proteins
-
McCormick PJ, Miao Y, Shao Y, Lin J, Johnson AE (2003) Cotranslational protein integration into the ER membrane is mediated by the binding of nascent chains to translocon proteins. Mol Cell 12(2-329-341
-
(2003)
Mol Cell
, vol.12
, Issue.2
, pp. 329-341
-
-
McCormick, P.J.1
Miao, Y.2
Shao, Y.3
Lin, J.4
Johnson, A.E.5
-
14
-
-
27144549973
-
Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein
-
Sadlish H, Pitonzo D, Johnson AE, Skach WR (2005) Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein. Nat Struct Mol Biol 12(10-870-878
-
(2005)
Nat Struct Mol Biol
, vol.12
, Issue.10
, pp. 870-878
-
-
Sadlish, H.1
Pitonzo, D.2
Johnson, A.E.3
Skach, W.R.4
-
15
-
-
77952378779
-
The hydrophobic core of the Sec61 translocon defines the hydrophobicity threshold for membrane integration
-
Junne T, Kocik L, Spiess M (2010) The hydrophobic core of the Sec61 translocon defines the hydrophobicity threshold for membrane integration. Mol Biol Cell 21(10- 1662-1670
-
(2010)
Mol Biol Cell
, vol.21
, Issue.10
, pp. 1662-1670
-
-
Junne, T.1
Kocik, L.2
Spiess, M.3
-
16
-
-
80053971494
-
Transmembrane segments of nascent polytopic membrane proteins control cytosol/ER targeting during membrane integration
-
Lin P-J, Jongsma CG, Liao S, Johnson AE (2011) Transmembrane segments of nascent polytopic membrane proteins control cytosol/ER targeting during membrane integration. J Cell Biol 195(1-41-54
-
(2011)
J Cell Biol
, vol.195
, Issue.1
, pp. 41-54
-
-
Lin, P.-J.1
Jongsma, C.G.2
Liao, S.3
Johnson, A.E.4
-
17
-
-
80053991771
-
Polytopic membrane protein folding at L17 in the ribosome tunnel initiates cyclical changes at the translocon
-
Lin P-J, Jongsma CG, Pool MR, Johnson AE (2011) Polytopic membrane protein folding at L17 in the ribosome tunnel initiates cyclical changes at the translocon. J Cell Biol 195(1-55-70
-
(2011)
J Cell Biol
, vol.195
, Issue.1
, pp. 55-70
-
-
Lin, P.-J.1
Jongsma, C.G.2
Pool, M.R.3
Johnson, A.E.4
-
18
-
-
61949084073
-
Sequence-specific retention and regulated integration of a nascent membrane protein by the endoplasmic reticulum Sec61 translocon
-
Pitonzo D, Yang Z, Matsumura Y, Johnson AE, Skach WR (2009) Sequence-specific retention and regulated integration of a nascent membrane protein by the endoplasmic reticulum Sec61 translocon. Mol Biol Cell 20(2-685-698
-
(2009)
Mol Biol Cell
, vol.20
, Issue.2
, pp. 685-698
-
-
Pitonzo, D.1
Yang, Z.2
Matsumura, Y.3
Johnson, A.E.4
Skach, W.R.5
-
19
-
-
77950448361
-
Hydrophobically stabilized open state for the lateral gate of the Sec translocon
-
Zhang B, Miller TF, 3rd (2010) Hydrophobically stabilized open state for the lateral gate of the Sec translocon. Proc Natl Acad Sci USA 107(12-5399-5404
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.12
, pp. 5399-5404
-
-
Zhang, B.1
Miller III, T.F.2
-
20
-
-
84865443871
-
Direct simulation of early-stage Sec-facilitated protein translocation
-
Zhang B, Miller TF, 3rd (2012) Direct simulation of early-stage Sec-facilitated protein translocation. J Am Chem Soc 134(33-13700-13707
-
(2012)
J Am Chem Soc
, vol.134
, Issue.33
, pp. 13700-13707
-
-
Zhang, B.1
Miller III, T.F.2
-
21
-
-
84868136627
-
Long-timescale dynamics and regulation of Sec-facilitated protein translocation
-
Zhang B, Miller TF, 3rd (2012) Long-timescale dynamics and regulation of Sec-facilitated protein translocation. Cell Rep 2(4-927-937
-
(2012)
Cell Rep
, vol.2
, Issue.4
, pp. 927-937
-
-
Zhang, B.1
Miller Iiii, T.F.2
-
22
-
-
84872194046
-
Exploring the nature of the translocon-assisted protein insertion
-
Rychkova A, Warshel A (2013) Exploring the nature of the translocon-assisted protein insertion. Proc Natl Acad Sci USA 110(2-495-500
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.2
, pp. 495-500
-
-
Rychkova, A.1
Warshel, A.2
-
23
-
-
78049245511
-
A comprehensive, quantitative, and genome-wide model of translation
-
Siwiak M, Zielenkiewicz P (2010) A comprehensive, quantitative, and genome-wide model of translation. PLOS Comput Biol 6(7-e1000865
-
(2010)
PLOS Comput Biol
, vol.6
, Issue.7
-
-
Siwiak, M.1
Zielenkiewicz, P.2
-
24
-
-
85027919032
-
Cryo-EM structure of the ribosome-SecYE complex in the membrane environment
-
Frauenfeld J, et al. (2011) Cryo-EM structure of the ribosome-SecYE complex in the membrane environment. Nat Struct Mol Biol 18(5-614-621
-
(2011)
Nat Struct Mol Biol
, vol.18
, Issue.5
, pp. 614-621
-
-
Frauenfeld, J.1
-
25
-
-
84861167327
-
Structure of the SecY complex unlocked by a preprotein mimic
-
Hizlan D, et al. (2012) Structure of the SecY complex unlocked by a preprotein mimic. Cell Rep 1(1-21-28
-
(2012)
Cell Rep
, vol.1
, Issue.1
, pp. 21-28
-
-
Hizlan, D.1
-
26
-
-
77954912142
-
Immobilization of the plug domain inside the SecY channel allows unrestricted protein translocation
-
Lycklama A Nijeholt JA, Bulacu M, Marrink SJ, Driessen AJM (2010) Immobilization of the plug domain inside the SecY channel allows unrestricted protein translocation. J Biol Chem 285(31-23747-23754
-
(2010)
J Biol Chem
, vol.285
, Issue.31
, pp. 23747-23754
-
-
Lycklama Nijeholt, A.J.A.1
Bulacu, M.2
Marrink, S.J.3
Ajm, D.4
-
27
-
-
83755168976
-
Conformational dynamics of the plug domain of the SecYEG protein-conducting channel
-
Lycklama a Nijeholt JA, Wu ZC, Driessen AJM (2011) Conformational dynamics of the plug domain of the SecYEG protein-conducting channel. J Biol Chem 286(51- 43881-43890
-
(2011)
J Biol Chem
, vol.286
, Issue.51
, pp. 43881-43890
-
-
Lycklama, A.1
Nijeholt, J.A.2
Wu, Z.C.3
Ajm, D.4
-
28
-
-
79955911333
-
Free energy of nascent-chain folding in the translocon
-
Gumbart J, Chipot C, Schulten K (2011) Free energy of nascent-chain folding in the translocon. J Am Chem Soc 133(19-7602-7607
-
(2011)
J Am Chem Soc
, vol.133
, Issue.19
, pp. 7602-7607
-
-
Gumbart, J.1
Chipot, C.2
Schulten, K.3
-
29
-
-
78049253482
-
Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes
-
Egea PF, Stroud RM (2010) Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes. Proc Natl Acad Sci USA 107(40- 17182-17187
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.40
, pp. 17182-17187
-
-
Egea, P.F.1
Stroud, R.M.2
-
30
-
-
0030789680
-
Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation
-
Pilon M, Schekman R, Romisch K (1997) Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation. EMBO J 16(15-4540-4548
-
(1997)
EMBO J
, vol.16
, Issue.15
, pp. 4540-4548
-
-
Pilon, M.1
Schekman, R.2
Romisch, K.3
-
31
-
-
0347192985
-
X-ray structure of a protein-conducting channel
-
Van den Berg B, et al. (2004) X-ray structure of a protein-conducting channel. Nature 427(6969-36-44
-
(2004)
Nature
, vol.427
, Issue.6969
, pp. 36-44
-
-
Van Den Berg, B.1
-
32
-
-
47149096704
-
CHARMM-GUI: A web-based graphical user interface for CHARMM
-
Jo S, Kim T, Iyer VG, ImW (2008) CHARMM-GUI: A web-based graphical user interface for CHARMM. J Comput Chem 29(11-1859-1865
-
(2008)
J Comput Chem
, vol.29
, Issue.11
, pp. 1859-1865
-
-
Jo, S.1
Kim, T.2
Iyer, V.G.3
Im, W.4
-
33
-
-
27344436659
-
Scalable molecular dynamics with NAMD
-
Phillips JC, et al. (2005) Scalable molecular dynamics with NAMD. J Comput Chem 26(16-1781-1802
-
(2005)
J Comput Chem
, vol.26
, Issue.16
, pp. 1781-1802
-
-
Phillips, J.C.1
-
34
-
-
0041784950
-
All-atom empirical potential for molecular modeling and dynamics studies of proteins
-
MacKerell AD, Jr., et al. (1998) All-atom empirical potential for molecular modeling and dynamics studies of proteins. J Phys Chem B 102:3586-3616.
-
(1998)
J Phys Chem B
, vol.102
, pp. 3586-3616
-
-
MacKerell Jr., A.D.1
|