Reconciling the roles of kinetic and thermodynamic factors in membrane-protein insertion

Journal of the American Chemical Society

Volumn 135, Issue 6, 2013, Pages 2291-2297

  Gumbart, James C ^a   Teo, Ivan ^b   Roux, Benoiît ^c   Schulten, Klaus ^b  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b University of Illinois at Urbana Champaign   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BI-LAYER; FREE-ENERGY DIFFERENCE; KINETIC FACTORS; MEMBRANE INSERTION; MEMBRANE PROTEINS; MOLECULAR DYNAMICS SIMULATIONS; MOLECULAR LEVELS; NASCENT PROTEIN; PARTITION SCHEMES; POTENTIAL OF MEAN FORCE; PROTEIN-CONDUCTING CHANNELS; THERMODYNAMIC FACTORS; TIME-DEPENDENT; TIME-SCALES; TRANSLOCON; TRANSMEMBRANE SEGMENTS; TWO-STATE;

BIOLOGICAL MEMBRANES; FREE ENERGY; KINETICS; MOLECULAR DYNAMICS; PROTEINS;

MEMBRANES;

BACTERIAL PROTEIN; MEMBRANE PROTEIN; SECY PROTEIN;

AQUEOUS SOLUTION; ARTICLE; ATOM; CALCULATION; CATALYSIS; CHANNEL GATING; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; ENERGY TRANSFER; FORCE; HYDROPHOBICITY; MEMBRANE PROTEIN INSERTION; MOLECULAR DYNAMICS; PARTITION COEFFICIENT; POTENTIAL OF MEAN FORCE; PROBABILITY; RIBOSOME; THERMODYNAMICS;

HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; THERMODYNAMICS;

EID: 84873675862     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja310777k     Document Type: Article

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