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Volumn 26, Issue 10, 2011, Pages 1943-1947

Long-term neuroprotection and neurorestoration by glial cell-derived neurotrophic factor microspheres for the treatment of Parkinson's disease

Author keywords

6 hydroxydopamine; Glial cell derived neurotrophic factor; Microspheres; Neurodegeneration; Parkinson's disease; Tyrosine hydroxylase

Indexed keywords

AMPHETAMINE; MICROSPHERE; OXIDOPAMINE; POLYGLACTIN; RECOMBINANT GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; RECOMBINANT GROWTH FACTOR; RHODAMINE; UNCLASSIFIED DRUG;

EID: 80052262622     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.23793     Document Type: Article
Times cited : (46)

References (29)
  • 1
    • 0027285510 scopus 로고
    • GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 1993; 260: 1130-1132.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 2
    • 0028834063 scopus 로고
    • Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo
    • Tomac A, Lindqvist E, Lin LF, et al. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature 1995; 373: 335-339.
    • (1995) Nature , vol.373 , pp. 335-339
    • Tomac, A.1    Lindqvist, E.2    Lin, L.F.3
  • 3
    • 13344277993 scopus 로고    scopus 로고
    • Functional recovery in parkinsonian monkeys treated with GDNF
    • Gash DM, Zhang Z, Ovadia A, et al. Functional recovery in parkinsonian monkeys treated with GDNF. Nature 1996; 380: 252-255.
    • (1996) Nature , vol.380 , pp. 252-255
    • Gash, D.M.1    Zhang, Z.2    Ovadia, A.3
  • 4
    • 0034672304 scopus 로고    scopus 로고
    • Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV, and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model
    • Björklund AKD, Rosenblad C, Georgievska B, Lundberg C, Mandel RJ. Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV, and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat Parkinson model. Brain Res 2000; 886: 82-98.
    • (2000) Brain Res , vol.886 , pp. 82-98
    • Björklund, A.K.D.1    Rosenblad, C.2    Georgievska, B.3    Lundberg, C.4    Mandel, R.J.5
  • 5
    • 0032850453 scopus 로고    scopus 로고
    • Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease
    • Kordower JH, Palfi S, Chen EY, et al. Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease. Ann Neurol 1999; 46: 419-424.
    • (1999) Ann Neurol , vol.46 , pp. 419-424
    • Kordower, J.H.1    Palfi, S.2    Chen, E.Y.3
  • 6
    • 0037435511 scopus 로고    scopus 로고
    • Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD
    • Nutt JG, Burchiel KJ, Comella CL, et al. Randomized, double-blind trial of glial cell line-derived neurotrophic factor (GDNF) in PD. Neurology 2003; 60: 69-73.
    • (2003) Neurology , vol.60 , pp. 69-73
    • Nutt, J.G.1    Burchiel, K.J.2    Comella, C.L.3
  • 7
    • 0142106351 scopus 로고    scopus 로고
    • Novel functions and signalling pathways for GDNF
    • Sariola H, Saarma M. Novel functions and signalling pathways for GDNF. J Cell Sci 2003; 116: 3855-3862.
    • (2003) J Cell Sci , vol.116 , pp. 3855-3862
    • Sariola, H.1    Saarma, M.2
  • 8
    • 1642499508 scopus 로고    scopus 로고
    • Localized striatal delivery of GDNF as a treatment for Parkinson disease
    • Kirik D, Georgievska B, Bjorklund A. Localized striatal delivery of GDNF as a treatment for Parkinson disease. Nat Neurosci 2004; 7: 105-110.
    • (2004) Nat Neurosci , vol.7 , pp. 105-110
    • Kirik, D.1    Georgievska, B.2    Bjorklund, A.3
  • 9
    • 0038249170 scopus 로고    scopus 로고
    • Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
    • Gill SS, Patel NK, Hotton GR, et al. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med 2003; 9: 589-595.
    • (2003) Nat Med , vol.9 , pp. 589-595
    • Gill, S.S.1    Patel, N.K.2    Hotton, G.R.3
  • 10
    • 14844311296 scopus 로고    scopus 로고
    • Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor
    • Slevin JT, Gerhardt GA, Smith CD, Gash DM, Kryscio R, Young B. Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor. J Neurosurg 2005; 102: 216-222.
    • (2005) J Neurosurg , vol.102 , pp. 216-222
    • Slevin, J.T.1    Gerhardt, G.A.2    Smith, C.D.3    Gash, D.M.4    Kryscio, R.5    Young, B.6
  • 11
    • 33644833272 scopus 로고    scopus 로고
    • Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease
    • Lang AE, Gill S, Patel NK, et al. Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease. Ann Neurol 2006; 59: 459-466.
    • (2006) Ann Neurol , vol.59 , pp. 459-466
    • Lang, A.E.1    Gill, S.2    Patel, N.K.3
  • 12
    • 34648834760 scopus 로고    scopus 로고
    • Purification of bioactive glycosylated recombinant glial cell line-derived neurotrophic factor
    • Garbayo E, Ansorena E, Lanciego JL, Aymerich MS, Blanco-Prieto MJ. Purification of bioactive glycosylated recombinant glial cell line-derived neurotrophic factor. Int J Pharm 2007; 344: 9-15.
    • (2007) Int J Pharm , vol.344 , pp. 9-15
    • Garbayo, E.1    Ansorena, E.2    Lanciego, J.L.3    Aymerich, M.S.4    Blanco-Prieto, M.J.5
  • 13
    • 48149090216 scopus 로고    scopus 로고
    • Sustained release of bioactive glycosylated glial cell-line derived neurotrophic factor from biodegradable polymeric microspheres
    • Garbayo E, Ansorena E, Lanciego JL, Aymerich MS, Blanco-Prieto MJ. Sustained release of bioactive glycosylated glial cell-line derived neurotrophic factor from biodegradable polymeric microspheres. Eur J Pharm Biopharm 2008; 69: 844-851.
    • (2008) Eur J Pharm Biopharm , vol.69 , pp. 844-851
    • Garbayo, E.1    Ansorena, E.2    Lanciego, J.L.3    Aymerich, M.S.4    Blanco-Prieto, M.J.5
  • 16
    • 0036434879 scopus 로고    scopus 로고
    • Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer
    • Georgievska B, Kirik D, Bjorklund A. Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer. Exp Neurol 2002; 177: 461-474.
    • (2002) Exp Neurol , vol.177 , pp. 461-474
    • Georgievska, B.1    Kirik, D.2    Bjorklund, A.3
  • 17
    • 3042770773 scopus 로고    scopus 로고
    • Striatal GDNF administration increases tyrosine hydroxylase phosphorylation in the rat striatum and substantia nigra
    • Salvatore MF, Zhang JL, Large DM, et al. Striatal GDNF administration increases tyrosine hydroxylase phosphorylation in the rat striatum and substantia nigra. J Neurochem 2004; 90: 245-254.
    • (2004) J Neurochem , vol.90 , pp. 245-254
    • Salvatore, M.F.1    Zhang, J.L.2    Large, D.M.3
  • 18
    • 68549096006 scopus 로고    scopus 로고
    • Bilateral effects of unilateral GDNF administration on dopamine- and GABA-regulating proteins in the rat nigrostriatal system
    • Salvatore MF, Gerhardt GA, Dayton RD, Klein RL, Stanford JA. Bilateral effects of unilateral GDNF administration on dopamine- and GABA-regulating proteins in the rat nigrostriatal system. Exp Neurol 2009; 219: 197-207.
    • (2009) Exp Neurol , vol.219 , pp. 197-207
    • Salvatore, M.F.1    Gerhardt, G.A.2    Dayton, R.D.3    Klein, R.L.4    Stanford, J.A.5
  • 19
    • 13444254008 scopus 로고    scopus 로고
    • Local and sustained delivery of 5-fluorouracil from biodegradable microspheres for the radiosensitization of malignant glioma: a randomized phase II trial
    • discussion, 242-248.
    • Menei P, Capelle L, Guyotat J, et al. Local and sustained delivery of 5-fluorouracil from biodegradable microspheres for the radiosensitization of malignant glioma: a randomized phase II trial. Neurosurgery 2005; 56: 242-248; discussion, 242-248.
    • (2005) Neurosurgery , vol.56 , pp. 242-248
    • Menei, P.1    Capelle, L.2    Guyotat, J.3
  • 20
    • 23644435297 scopus 로고    scopus 로고
    • Drug delivery into the brain using poly(lactide-co-glycolide) microspheres
    • Menei P, Montero-Menei C, Venier MC, Benoit JP. Drug delivery into the brain using poly(lactide-co-glycolide) microspheres. Exp Opin Drug Deliv 2005; 2: 363-376.
    • (2005) Exp Opin Drug Deliv , vol.2 , pp. 363-376
    • Menei, P.1    Montero-Menei, C.2    Venier, M.C.3    Benoit, J.P.4
  • 21
    • 0029047329 scopus 로고
    • Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion
    • Sauer H, Rosenblad C, Bjorklund A. Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proc Natl Acad Sci U S A 1995; 92: 8935-8939.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8935-8939
    • Sauer, H.1    Rosenblad, C.2    Bjorklund, A.3
  • 22
    • 0030774588 scopus 로고    scopus 로고
    • GDNF protection against 6-OHDA: time dependence and requirement for protein synthesis
    • Kearns CM, Cass WA, Smoot K, Kryscio R, Gash DM. GDNF protection against 6-OHDA: time dependence and requirement for protein synthesis. J Neurosci 1997; 17: 7111-7118.
    • (1997) J Neurosci , vol.17 , pp. 7111-7118
    • Kearns, C.M.1    Cass, W.A.2    Smoot, K.3    Kryscio, R.4    Gash, D.M.5
  • 23
    • 0031840772 scopus 로고    scopus 로고
    • Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line-derived neurotrophic factor against 6-hydroxydopamine in vivo
    • Sullivan AM, Opacka-Juffry J, Blunt SB. Long-term protection of the rat nigrostriatal dopaminergic system by glial cell line-derived neurotrophic factor against 6-hydroxydopamine in vivo. Eur J Neurosci 1998; 10: 57-63.
    • (1998) Eur J Neurosci , vol.10 , pp. 57-63
    • Sullivan, A.M.1    Opacka-Juffry, J.2    Blunt, S.B.3
  • 24
    • 0033773237 scopus 로고    scopus 로고
    • Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor
    • Kirik D, Rosenblad C, Bjorklund A. Preservation of a functional nigrostriatal dopamine pathway by GDNF in the intrastriatal 6-OHDA lesion model depends on the site of administration of the trophic factor. Eur J Neurosci 2000; 12: 3871-3882.
    • (2000) Eur J Neurosci , vol.12 , pp. 3871-3882
    • Kirik, D.1    Rosenblad, C.2    Bjorklund, A.3
  • 25
    • 34047220707 scopus 로고    scopus 로고
    • Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal
    • Slevin JT, Gash DM, Smith CD, et al. Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal. J Neurosurg 2007; 106: 614-620.
    • (2007) J Neurosurg , vol.106 , pp. 614-620
    • Slevin, J.T.1    Gash, D.M.2    Smith, C.D.3
  • 26
    • 72449188768 scopus 로고    scopus 로고
    • Reversible neurochemical changes mediated by delayed intrastriatal glial cell line-derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model
    • Yang X, Mertens B, Lehtonen E, et al. Reversible neurochemical changes mediated by delayed intrastriatal glial cell line-derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model. J Gene Med 2009; 11: 899-912.
    • (2009) J Gene Med , vol.11 , pp. 899-912
    • Yang, X.1    Mertens, B.2    Lehtonen, E.3
  • 27
    • 39649109499 scopus 로고    scopus 로고
    • Development of a maturing T-cell-mediated immune response in patients with idiopathic Parkinson's disease receiving r-metHuGDNF via continuous intraputaminal infusion
    • Tatarewicz SM, Wei X, Gupta S, Masterman D, Swanson SJ, Moxness MS. Development of a maturing T-cell-mediated immune response in patients with idiopathic Parkinson's disease receiving r-metHuGDNF via continuous intraputaminal infusion. J Clin Immunol 2007; 27: 620-627.
    • (2007) J Clin Immunol , vol.27 , pp. 620-627
    • Tatarewicz, S.M.1    Wei, X.2    Gupta, S.3    Masterman, D.4    Swanson, S.J.5    Moxness, M.S.6
  • 28
    • 57749176448 scopus 로고    scopus 로고
    • Striatal volume differences between non-human and human primates
    • Yin D, Valles FE, Fiandaca MS, et al. Striatal volume differences between non-human and human primates. J Neurosci Meth 2009; 176: 200-205.
    • (2009) J Neurosci Meth , vol.176 , pp. 200-205
    • Yin, D.1    Valles, F.E.2    Fiandaca, M.S.3
  • 29
    • 0033544840 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer
    • Bemelmans AP, Horellou P, Pradier L, Brunet I, Colin P, Mallet J. Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer. Hum Gene Ther 1999; 10: 2987-2997.
    • (1999) Hum Gene Ther , vol.10 , pp. 2987-2997
    • Bemelmans, A.P.1    Horellou, P.2    Pradier, L.3    Brunet, I.4    Colin, P.5    Mallet, J.6


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