Changing hydration level in an internal cavity modulates the proton affinity of a key glutamate in cytochrome c oxidase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 47, 2013, Pages 18886-18891

  Goyal, Puja ^a   Lu, Jianxun ^b   Yang, Shuo ^a   Gunner, M R ^b   Cui, Qiang ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b CITY COLLEGE OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; GLUTAMIC ACID; HEME; PROPIONIC ACID; PROTON; WATER;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIELECTRIC CONSTANT; ELECTRON TRANSPORT; HYDRATION; HYDROPHOBICITY; IONIZATION; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTON TRANSPORT; STATIC ELECTRICITY; TITRIMETRY;

PKA; PROTON PUMPING;

COMPUTATIONAL BIOLOGY; ELECTRON TRANSPORT COMPLEX IV; GLUTAMIC ACID; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PROTONS; RHODOBACTER SPHAEROIDES; STATIC ELECTRICITY;

EID: 84888093711     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1313908110     Document Type: Article

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