Adenovirus E4orf4 protein-induced death of p53-/- H1299 human cancer cells follows a G1 arrest of both tetraploid and diploid cells due to a failure to initiate DNA synthesis

Journal of Virology

Volumn 87, Issue 24, 2013, Pages 13168-13178

  Cabon, Lauriane ^a,c   Sriskandarajah, Neera ^a   Mui, Melissa Z ^a   Teodoro, Jose G ^a,b   Blanchette, Paola ^a   Branton, Philip E ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c CENTRE DE RECHERCHE DES CORDELIERS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; PROTEIN E4ORF4; PROTEIN P53; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENOVIRUS 2; ARTICLE; BIOACCUMULATION; CARCINOMA CELL; CELL DEATH; CELL STRAIN; CELL STRAIN H1299; CONTROLLED STUDY; DIPLOIDY; DNA SYNTHESIS INHIBITION; DRUG MECHANISM; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; LUNG CARCINOMA; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TETRAPLOIDY;

ADENOVIRUS INFECTIONS, HUMAN; ADENOVIRUSES, HUMAN; ANIMALS; APOPTOSIS; CELL DEATH; CELL LINE, TUMOR; DIPLOIDY; DNA; DNA REPLICATION; G1 PHASE CELL CYCLE CHECKPOINTS; GENE KNOCKOUT TECHNIQUES; HUMANS; TETRAPLOIDY; TUMOR SUPPRESSOR PROTEIN P53; VIRAL PROTEINS;

EID: 84888043307     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01242-13     Document Type: Article

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