메뉴 건너뛰기




Volumn 133, Issue 5, 2013, Pages 1064-1073

MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A

Author keywords

epigenetics; LSD1; miR 137; neuroblastoma

Indexed keywords

HISTONE DEMETHYLASE; MESSENGER RNA; MICRORNA; MICRORNA 137; PROTEIN KDM1A; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84879230729     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28091     Document Type: Article
Times cited : (95)

References (34)
  • 2
    • 77953523121 scopus 로고    scopus 로고
    • Recent advances in neuroblastoma
    • Maris JM,. Recent advances in neuroblastoma. N Engl J Med 2010; 362: 2202-11.
    • (2010) N Engl J Med , vol.362 , pp. 2202-2211
    • Maris, J.M.1
  • 4
    • 37549052922 scopus 로고    scopus 로고
    • Expression of KIT and PDGFR is associated with a good prognosis in neuroblastoma
    • Shimada A, Hirato J, Kuroiwa M, et al. Expression of KIT and PDGFR is associated with a good prognosis in neuroblastoma. Pediatr Blood Cancer 2008; 50: 213-7.
    • (2008) Pediatr Blood Cancer , vol.50 , pp. 213-217
    • Shimada, A.1    Hirato, J.2    Kuroiwa, M.3
  • 5
    • 0027531016 scopus 로고
    • Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma
    • Nakagawara A, Arima-Nakagawara M, Scavarda NJ, et al. Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma. N Engl J Med 1993; 328: 847-54.
    • (1993) N Engl J Med , vol.328 , pp. 847-854
    • Nakagawara, A.1    Arima-Nakagawara, M.2    Scavarda, N.J.3
  • 6
    • 11144332565 scopus 로고    scopus 로고
    • Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
    • Shi Y, Lan F, Matson C, et al. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 2004; 119: 941-53.
    • (2004) Cell , vol.119 , pp. 941-953
    • Shi, Y.1    Lan, F.2    Matson, C.3
  • 7
    • 58149156264 scopus 로고    scopus 로고
    • The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation
    • Wang J, Hevi S, Kurash JK, et al. The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nat Genet 2009; 41: 125-9.
    • (2009) Nat Genet , vol.41 , pp. 125-129
    • Wang, J.1    Hevi, S.2    Kurash, J.K.3
  • 8
    • 84859867217 scopus 로고    scopus 로고
    • Breaking the LSD1/KDM1A addiction: Therapeutic targeting of the epigenetic modifier in AML
    • Lokken AA, Zeleznik-Le NJ,. Breaking the LSD1/KDM1A addiction: therapeutic targeting of the epigenetic modifier in AML. Cancer Cell 2012; 21: 451-3.
    • (2012) Cancer Cell , vol.21 , pp. 451-453
    • Lokken, A.A.1    Zeleznik-Le, N.J.2
  • 9
    • 84887018119 scopus 로고    scopus 로고
    • Lysine-specific demethylase 1 (LSD1/KDM1A/AOF2/BHC110) is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma
    • Bennani-Baiti IM, Machado I, Llombart-Bosch A, et al. Lysine-specific demethylase 1 (LSD1/KDM1A/AOF2/BHC110) is expressed and is an epigenetic drug target in chondrosarcoma, Ewing's sarcoma, osteosarcoma, and rhabdomyosarcoma. Hum Pathol, in press.
    • Hum Pathol
    • Bennani-Baiti, I.M.1    MacHado, I.2    Llombart-Bosch, A.3
  • 10
    • 73749085827 scopus 로고    scopus 로고
    • H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1
    • Magerl C, Ellinger J, Braunschweig T, et al. H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1. Hum Pathol 2010; 41: 181-9.
    • (2010) Hum Pathol , vol.41 , pp. 181-189
    • Magerl, C.1    Ellinger, J.2    Braunschweig, T.3
  • 11
    • 78649815150 scopus 로고    scopus 로고
    • Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers
    • Hayami S, Kelly JD, Cho HS, et al. Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. Int J Cancer 2011; 128: 574-86.
    • (2011) Int J Cancer , vol.128 , pp. 574-586
    • Hayami, S.1    Kelly, J.D.2    Cho, H.S.3
  • 12
    • 33845762289 scopus 로고    scopus 로고
    • Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence
    • Kahl P, Gullotti L, Heukamp LC, et al. Androgen receptor coactivators lysine-specific histone demethylase 1 and four and a half LIM domain protein 2 predict risk of prostate cancer recurrence. Cancer Res 2006; 66: 11341-7.
    • (2006) Cancer Res , vol.66 , pp. 11341-11347
    • Kahl, P.1    Gullotti, L.2    Heukamp, L.C.3
  • 13
    • 77950868547 scopus 로고    scopus 로고
    • Lysine-Specific Demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology
    • Lim S, Janzer A, Becker A, et al. Lysine-Specific Demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology. Carcinogenesis 2010; 31: 512-20.
    • (2010) Carcinogenesis , vol.31 , pp. 512-520
    • Lim, S.1    Janzer, A.2    Becker, A.3
  • 14
    • 84862777766 scopus 로고    scopus 로고
    • Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
    • Schenk T, Chen WC, Gollner S, et al. Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia. Nat Med 2012; 18: 605-11.
    • (2012) Nat Med , vol.18 , pp. 605-611
    • Schenk, T.1    Chen, W.C.2    Gollner, S.3
  • 15
    • 62449197931 scopus 로고    scopus 로고
    • Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: Implications for therapy
    • Schulte JH, Lim S, Schramm A, et al. Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy. Cancer Res 2009; 69: 2065-71.
    • (2009) Cancer Res , vol.69 , pp. 2065-2071
    • Schulte, J.H.1    Lim, S.2    Schramm, A.3
  • 16
    • 33747876113 scopus 로고    scopus 로고
    • MicroRNA-cancer connection: The beginning of a new tale
    • Calin GA, Croce CM,. MicroRNA-cancer connection: the beginning of a new tale. Cancer Res 2006; 66: 7390-4.
    • (2006) Cancer Res , vol.66 , pp. 7390-7394
    • Calin, G.A.1    Croce, C.M.2
  • 17
    • 57749088707 scopus 로고    scopus 로고
    • MicroRNAs in the pathogenesis of neuroblastoma
    • Schulte JH, Horn S, Schlierf S, et al. MicroRNAs in the pathogenesis of neuroblastoma. Cancer Lett 2009; 274: 10-5.
    • (2009) Cancer Lett , vol.274 , pp. 10-15
    • Schulte, J.H.1    Horn, S.2    Schlierf, S.3
  • 19
    • 77955439834 scopus 로고    scopus 로고
    • Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma
    • Schulte JH, Marschall T, Martin M, et al. Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma. Nucleic Acids Res 2010; 38: 5919-28.
    • (2010) Nucleic Acids Res , vol.38 , pp. 5919-5928
    • Schulte, J.H.1    Marschall, T.2    Martin, M.3
  • 20
    • 77955438409 scopus 로고    scopus 로고
    • Accurate prediction of neuroblastoma outcome based on miRNA expression profiles
    • Schulte JH, Schowe B, Mestdagh P, et al. Accurate prediction of neuroblastoma outcome based on miRNA expression profiles. Int J Cancer 2010; 127: 2374-85.
    • (2010) Int J Cancer , vol.127 , pp. 2374-2385
    • Schulte, J.H.1    Schowe, B.2    Mestdagh, P.3
  • 21
    • 33847009923 scopus 로고    scopus 로고
    • Differential patterns of MicroRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis
    • Chen Y, Stallings RL,. Differential patterns of MicroRNA expression in neuroblastoma are correlated with prognosis, differentiation, and apoptosis. Cancer Res 2007; 67: 976-83.
    • (2007) Cancer Res , vol.67 , pp. 976-983
    • Chen, Y.1    Stallings, R.L.2
  • 22
    • 84868210731 scopus 로고    scopus 로고
    • LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
    • Molenaar JJ, Domingo-Fernandez R, Ebus ME, et al. LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression. Nat Genet 2012; 44: 1199-206.
    • (2012) Nat Genet , vol.44 , pp. 1199-1206
    • Molenaar, J.J.1    Domingo-Fernandez, R.2    Ebus, M.E.3
  • 23
    • 37349080954 scopus 로고    scopus 로고
    • MYCN regulates oncogenic MicroRNAs in neuroblastoma
    • Schulte JH, Horn S, Otto T, et al. MYCN regulates oncogenic MicroRNAs in neuroblastoma. Int J Cancer 2008; 122: 699-704.
    • (2008) Int J Cancer , vol.122 , pp. 699-704
    • Schulte, J.H.1    Horn, S.2    Otto, T.3
  • 24
    • 78649941638 scopus 로고    scopus 로고
    • The miR-17-92 microRNA cluster regulates multiple components of the TGF-beta pathway in neuroblastoma
    • Mestdagh P, Bostrom AK, Impens F, et al. The miR-17-92 microRNA cluster regulates multiple components of the TGF-beta pathway in neuroblastoma. Mol Cell 2010; 40: 762-73.
    • (2010) Mol Cell , vol.40 , pp. 762-773
    • Mestdagh, P.1    Bostrom, A.K.2    Impens, F.3
  • 25
    • 40449094344 scopus 로고    scopus 로고
    • MicroRNA-137 targets microphthalmia-associated transcription factor in melanoma cell lines
    • Bemis LT, Chen R, Amato CM, et al. MicroRNA-137 targets microphthalmia-associated transcription factor in melanoma cell lines. Cancer Res 2008; 68: 1362-8.
    • (2008) Cancer Res , vol.68 , pp. 1362-1368
    • Bemis, L.T.1    Chen, R.2    Amato, C.M.3
  • 26
    • 42049104107 scopus 로고    scopus 로고
    • Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
    • Kozaki K, Imoto I, Mogi S, et al. Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res 2008; 68: 2094-105.
    • (2008) Cancer Res , vol.68 , pp. 2094-2105
    • Kozaki, K.1    Imoto, I.2    Mogi, S.3
  • 27
    • 48949116262 scopus 로고    scopus 로고
    • MiR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
    • Silber J, Lim DA, Petritsch C, et al. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med 2008; 6: 14.
    • (2008) BMC Med , vol.6 , pp. 14
    • Silber, J.1    Lim, D.A.2    Petritsch, C.3
  • 28
    • 82555196537 scopus 로고    scopus 로고
    • MiR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells
    • Sun G, Ye P, Murai K, et al. miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells. Nat Commun 2011; 2: 529.
    • (2011) Nat Commun , vol.2 , pp. 529
    • Sun, G.1    Ye, P.2    Murai, K.3
  • 29
    • 77955723545 scopus 로고    scopus 로고
    • Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis
    • Balaguer F, Link A, Lozano JJ, et al. Epigenetic silencing of miR-137 is an early event in colorectal carcinogenesis. Cancer Res 2010; 70: 6609-18.
    • (2010) Cancer Res , vol.70 , pp. 6609-6618
    • Balaguer, F.1    Link, A.2    Lozano, J.J.3
  • 30
    • 84858126071 scopus 로고    scopus 로고
    • MicroRNA dysregulation in cancer: Diagnostics, monitoring and therapeutics. A comprehensive review
    • Iorio MV, Croce CM,. MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol Med 2012; 4: 143-59.
    • (2012) EMBO Mol Med , vol.4 , pp. 143-159
    • Iorio, M.V.1    Croce, C.M.2
  • 31
    • 84861473531 scopus 로고    scopus 로고
    • Inhibition of neuroblastoma tumor growth by targeted delivery of microRNA-34a using anti-disialoganglioside GD2 coated nanoparticles
    • Tivnan A, Orr WS, Gubala V, et al. Inhibition of neuroblastoma tumor growth by targeted delivery of microRNA-34a using anti-disialoganglioside GD2 coated nanoparticles. PLoS One 2012; 7: e38129.
    • (2012) PLoS One , vol.7
    • Tivnan, A.1    Orr, W.S.2    Gubala, V.3
  • 32
    • 79951850875 scopus 로고    scopus 로고
    • MicroRNA-542-5p as a novel tumor suppressor in neuroblastoma
    • Bray I, Tivnan A, Bryan K, et al. MicroRNA-542-5p as a novel tumor suppressor in neuroblastoma. Cancer Lett 2011; 303: 56-64.
    • (2011) Cancer Lett , vol.303 , pp. 56-64
    • Bray, I.1    Tivnan, A.2    Bryan, K.3
  • 33
    • 78951477589 scopus 로고    scopus 로고
    • MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma
    • Tivnan A, Tracey L, Buckley PG, et al. MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma. BMC Cancer 2011; 11: 33.
    • (2011) BMC Cancer , vol.11 , pp. 33
    • Tivnan, A.1    Tracey, L.2    Buckley, P.G.3
  • 34
    • 77958150580 scopus 로고    scopus 로고
    • Targeting DNA methylation for epigenetic therapy
    • Yang X, Lay F, Han H, et al. Targeting DNA methylation for epigenetic therapy. Trends Pharmacol Sci 2010; 31: 536-46.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 536-546
    • Yang, X.1    Lay, F.2    Han, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.