Cloning and sequencing of the chaetocin biosynthetic gene cluster

ChemBioChem

Volumn 14, Issue 17, 2013, Pages 2256-2258

  Gerken, Thomas ^a,b   Walsh, Christopher T ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Metanomics GmbH   (Germany)

Author keywords

alkaloids; biosynthesis; chaetocin; epidithiodiketopiperazine; gliotoxin

Indexed keywords

CHETOCIN; DISULFIDE; EPIDITHIODIKETOPIPERAZINE; GLIOTOXIN; HISTONE METHYLTRANSFERASE; MYCOTOXIN; PIPERAZINEDIONE; THIOREDOXIN REDUCTASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC ION;

ARTICLE; BIOLOGICAL ACTIVITY; BIOSYNTHESIS; CHAETOMIUM; CHAETOMIUM VIRESCENS; ENZYME INHIBITION; FUNGAL GENE; GENE CLUSTER; GENE SEQUENCE; IMMUNOCOMPROMISED PATIENT; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPPORTUNISTIC INFECTION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL;

FUNGI;

ALKALOIDS; BIOSYNTHESIS; CHAETOCIN; EPIDITHIODIKETOPIPERAZINE; GLIOTOXIN;

BASE SEQUENCE; BIOSYNTHETIC PATHWAYS; CHAETOMIUM; CLONING, MOLECULAR; MULTIGENE FAMILY; PIPERAZINES;

EID: 84888004195     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201300513     Document Type: Article

References (27)

1. D. M. Gardiner, P. Waring, B. J. Howlett, Microbiology 2005, 151, 1021.
2. K. M. Cook, S. T. Hilton, J. Mecinovic, W. B. Motherwell, W. D. Figg, C. J. Schofield, J. Biol. Chem. 2009, 284, 26831.
3. D. M. Gardiner, A. J. Cozijnsen, L. M. Wilson, M. S. Pedras, B. J. Howlett, Mol. Microbiol. 2004, 53, 1307.
4. D. M. Gardiner, B. J. Howlett, FEMS Microbiol. Lett. 2005, 248, 241.
5. M. Schrettl, S. Carberry, K. Kavanagh, H. Haas, G. W. Jones, J. O'Brien, A. Nolan, J. Stephens, O. Fenelon, S. Doyle, PLoS Pathog. 2010, 6, e 100952.
6. D. H. Scharf, N. Remme, T. Heinekamp, P. Hortschansky, A. A. Brakhage, C. Hertweck, J. Am. Chem. Soc. 2010, 132, 10136.
7. C. Davis, S. Carberry, M. Schrettl, I. Singh, J. C. Stephens, S. M. Barry, K. Kavanagh, G. L. Challis, D. Brougham, S. Doyle, Chem. Biol. 2011, 18, 542.
8. D. H. Scharf, N. Remme, A. Habel, P. Chankhamjon, K. Scherlach, T. Heinekamp, P. Hortschansky, A. A. Brakhage, C. Hertweck, J. Am. Chem. Soc. 2011, 133, 12322.
9. D. H. Scharf, P. Chankhamjon, K. Scherlach, T. Heinekamp, M. Roth, A. A. Brakhage, C. Hertweck, Angew. Chem. 2012, 124, 10211
10. Angew. Chem. Int. Ed. 2012, 51, 10064.
11. D. Hauser, H. P. Weber, H. P. Sigg, Helv. Chim. Acta 1970, 53, 1061.
12. K. Katagiri, K. Sato, S. Hayakawa, T. Matsushima, H. Minato, J. Antibiot. 1970, 23, 420.
13. J. Kim, J. A. Ashenhurst, M. Movassaghi, Science 2009, 324, 238.
14. J. Kim, M. Movassaghi, J. Am. Chem. Soc. 2010, 132, 14376.
15. E. Iwasa, Y. Hamashima, S. Fujishiro, E. Higuchi, A. Ito, M. Yoshida, M. Sodeoka, J. Am. Chem. Soc. 2010, 132, 4078.
16. S. F. Altschul, W. Gish, W. Miller, E. W. Myers, D. J. Lipman, J. Mol. Biol. 1990, 215, 403.
17. C. J. Balibar, C. T. Walsh, Biochemistry 2006, 45, 15029.
18. A. Marchler-Bauer, C. Zheng, F. Chitsaz, M. K. Derbyshire, L. Y. Geer, R. C. Geer, N. R. Gonzales, M. Gwadz, D. I. Hurwitz, C. J. Lanczycki, F. Lu, S. Lu, G. H. Marchler, J. S. Song, N. Thanki, R. A. Yamashita, D. Zhang, S. H. Bryant, Nucleic Acids Res. 2013, 41, D 348.
19. R. Morgenstern, J. Zhang, K. Johansson, Drug Metab. Rev. 2011, 43, 300.
20. D. P. Dixon, M. Skipsey, R. Edwards, Phytochemistry 2010, 71, 338.
21. J. Kim, M. Movassaghi, Chem. Soc. Rev. 2009, 38, 3035.
22. J. Ma, Z. Wang, H. Huang, M. Luo, D. Zuo, B. Wang, A. Sun, Y.-Q. Cheng, C. Zhang, J. Ju, Angew. Chem. 2011, 123, 7943
23. Angew. Chem. Int. Ed. 2011, 50, 7797.
24. M. W. Jennison, M. D. Newcomb, R. Henderson, Mycologia 1955, 47, 275.
25. S. B. Lee, M. G. Milgroom, J. W. Taylor, Fungal Gen. Newsl. 1988, 35, 24.
26. S. Hrvatin, J. Piel, J. Microbiol. Methods 2007, 68, 434.
27. J. T. Simpson, K. Wong, S. D. Jackman, J. E. Schein, S. J. Jones, I. Birol, Genome Res. 2009, 19, 1117.