Polymorphisms in DNA repair genes, recreational physical activity and breast cancer risk

International Journal of Cancer

Volumn 134, Issue 3, 2014, Pages 654-663

  Mccullough, Lauren E ^a   Santella, Regina M ^b   Cleveland, Rebecca J ^c   Millikan, Robert C ^a   Olshan, Andrew F ^a   North, Kari E ^a   Bradshaw, Patrick T ^d   Eng, Sybil M ^b   Terry, Mary Beth ^b   Shen, Jing ^b   Crew, Katherine D ^e   Rossner, Pavel ^f   Teitelbaum, Susan L ^g   Neugut, Alfred I ^b,e   Gammon, Marilie D ^a  

^a University of North Carolina at Chapel Hill   (United States)

^b Department of Medicine   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d University of North Carolina   (United States)

^e New York Presbyterian Columbia University Medical Center   (United States)

^f INSTITUTE OF EXPERIMENTAL BOTANY   (Czech Republic)

^g MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

breast cancer; DNA repair; epidemiology; mismatch repair; physical activity

Indexed keywords

PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH3; XERODERMA PIGMENTOSUM GROUP C PROTEIN;

ADULT; AGED; ALLELE; ARTICLE; BREAST CANCER; CANCER INCIDENCE; CANCER RISK; CONTROLLED STUDY; DNA POLYMORPHISM; EXCISION REPAIR; FEMALE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; MAJOR CLINICAL STUDY; MISMATCH REPAIR; MLH1 GENE; MSH2 GENE; MSH3 GENE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RECREATION; RISK REDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; XPC GENE;

EID: 84887994113     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28383     Document Type: Article

References (51)

1. Cadenas E,. Biochemistry of oxygen toxicity. Annu Rev Biochem 1989; 58: 79-110.
2. Goode EL, Ulrich CM, Potter JD,. Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol Biomarkers Prev 2002 11: 1513-30.
3. Li GM,. Mechanisms and functions of DNA mismatch repair. Cell Res 2008; 18: 85-98.
4. Kolodner RD, Marsischky GT,. Eukaryotic DNA mismatch repair. Curr Opin Genet Dev 1999; 9: 89-96.
5. Baylin SB, Herman JG,. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000; 16: 168-74.
6. Herman JG, Baylin SB,. Promoter-region hypermethylation and gene silencing in human cancer. Curr Top Microbiol Immunol 2000; 249: 35-54.
7. Schofield MJ, Hsieh P,. DNA mismatch repair: molecular mechanisms and biological function. Annu Rev Microbiol 2003; 57: 579-608.
8. Strand M, Prolla TA, Liskay RM, et al. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair. Nature 1993; 365: 274-6.
9. Yee CJ, Roodi N, Verrier CS, et al. Microsatellite instability and loss of heterozygosity in breast cancer. Cancer Res 1994; 54: 1641-4.
10. Shaw JA, Walsh T, Chappell SA, et al. Microsatellite instability in early sporadic breast cancer. Br J Cancer 1996; 73: 1393-7.
11. Koster F, Schroer A, Fischer D, et al. Immunohistochemistry of proteins for DNA mismatch repair in correlation to prognostic factors of mammarian cancer. Oncol Rep 2007; 17: 1223-7.
12. Chintamani Jha BP, Bhandari V, Bansal A, et al. The expression of mismatched repair genes and their correlation with clinicopathological parameters and response to neo-adjuvant chemotherapy in breast cancer. Int Semin Surg Oncol 2007; 4: 5.
13. Poplawski T, Zadrozny M, Kolacinska A, et al. Polymorphisms of the DNA mismatch repair gene HMSH2 in breast cancer occurence and progression. Breast Cancer Res Treat 2005; 94: 199-204.
14. Lee KM, Choi JY, Kang C, et al. Genetic polymorphisms of selected DNA repair genes, estrogen and progesterone receptor status, and breast cancer risk. Clin Cancer Res 2005; 11: 4620-6.
15. Smith TR, Levine EA, Freimanis RI, et al. Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. Carcinogenesis 2008; 29: 2132-8.
16. Conde J, Silva SN, Azevedo AP, et al. Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study. BMC Cancer 2009; 9: 344.
17. Monsees GM, Kraft P, Chanock SJ, et al. Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk. Breast Cancer Res Treat 2011; 125: 207-14.
18. Berwick M, Vineis P,. Markers of DNA repair and susceptibility to cancer in humans: an epidemiologic review. J Natl Cancer Inst 2000; 92: 874-97.
19. Vani M, Reddy GP, Reddy GR, et al. Glutathione-S-transferase, superoxide dismutase, xanthine oxidase, catalase, glutathione peroxidase and lipid peroxidation in the liver of exercised rats. Biochem Int 1990; 21: 17-26.
20. Evelo CT, Palmen NG, Artur Y, et al. Changes in blood glutathione concentrations, and in erythrocyte glutathione reductase and glutathione S-transferase activity after running training and after participation in contests. Eur J Appl Physiol Occup Physiol 1992; 64: 354-8.
21. Radak Z, Taylor AW, Ohno H, et al. Adaptation to exercise-induced oxidative stress: from muscle to brain. Exerc Immunol Rev 2001; 7: 90-107.
22. Sato Y, Nanri H, Ohta M, et al. Increase of human MTH1 and decrease of 8-hydroxydeoxyguanosine in leukocyte DNA by acute and chronic exercise in healthy male subjects. Biochem Biophys Res Commun 2003; 305: 333-8.
23. Radak Z, Kaneko T, Tahara S, et al. The effect of exercise training on oxidative damage of lipids, proteins, and DNA in rat skeletal muscle: evidence for beneficial outcomes. Free Radic Biol Med 1999; 27: 69-74.
24. Radak Z, Pucsuk J, Boros S, et al. Changes in urine 8- hydroxydeoxyguanosine levels of super-marathon runners during a four-day race period. Life Sci 2000; 66: 1763-7.
25. Radak Z, Naito H, Kaneko T, et al. Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle. Pflugers Arch 2002; 445: 273-8.
26. Radak Z, Apor P, Pucsok J, et al. Marathon running alters the DNA base excision repair in human skeletal muscle. Life Sci 2003; 72: 1627-33.
27. Wittwer M, Billeter R, Hoppeler H, et al. Regulatory gene expression in skeletal muscle of highly endurance-trained humans. Acta Physiol Scand 2004; 180: 217-27.
28. Gammon MD, Neugut AI, Santella RM, et al. The long island breast cancer study project: description of a multi-institutional collaboration to identify environmental risk factors for breast cancer. Breast Cancer Res Treat 2002; 74: 235-54.
29. Nucleic Acids Research. [homepage on the Internet]. Available at: http://www.niehs.nih.gov/snpinfo.
30. International HapMap Consortium. The international HapMap project. Nature 2003; 426: 789-96.
31. Terry MB, Gammon MD, Zhang FF, et al. Polymorphism in the DNA repair gene XPD, polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, and breast cancer risk. Cancer Epidemiol Biomarkers Prev 2004; 13: 2053-8.
32. Chen X, Levine L, Kwok PY,. Fluorescence polarization in homogeneous nucleic acid analysis. Genome Res 1999; 9: 492-8.
33. Ahn J, Gammon MD, Santella RM, et al. Myeloperoxidase genotype, fruit and vegetable consumption, and breast cancer risk. Cancer Res 2004; 64: 7634-9.
34. Bernstein L, Henderson BE, Hanisch R, et al. Physical exercise and reduced risk of breast cancer in young women. J Natl Cancer Inst 1994; 86: 1403-8.
35. McCullough LE, Eng SM, Bradshaw PT, et al. Fat or fit: the joint effects of physical activity, weight gain, and body size on breast cancer risk. Cancer. 2012 Oct 1;1 18(19):4860-8. doi: 10.10021cncr.27433. Epub 2012 Jun 25. PubMed PMID: 22733561; PubMed Central PMCID: PMC3448867.
36. Ziegler A, Konig I,. A statistical approach to genetic epidemiology. New York: Wiley, 2006.
37. Kleinbaum DG, Klein M,. SurvivalAnalysis: A Self Learning Text. 2nd ed. New York: Springer, 2002.
38. Breslow NE, Day NE,. Statistical methods in cancer research, vol. 1-the analysis of case-control studies. IARC Sci Publ., Lyon, France. 1980. pp 5-338.
39. Yang XR, Chang-Claude J, Goode EL, et al. Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the breast cancer association consortium studies. J Natl Cancer Inst 2011; 103: 250-63.
40. Rothman K, Greenland S,. Modern epidemiology, 2nd edn. Philadelphia: Maple Press, 1998.
41. Mohrenweiser HW, Wilson DM, III, Jones IM,. Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes. Mutat Res 2003; 526: 93-125.
42. Greenland S,. Modeling and variable selection in epidemiologic analysis. Am J Public Health 1989; 79: 340-9.
43. Crew KD, Gammon MD, Terry MB, Zhang FF, Zablotska LB, Agrawal M, Shen J, Long CM, Eng SM, Sagiv SK, Teitelbaum SL, NeugutAl, Santella RM. Polymorphisms in nucleotide excision repair genes, polycyclic aromatic hydrocarbon-DNA adducts, and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2007 Oct;16(10):2033-41. PubMed PMID: 17932351.
44. Rossner P Jr, Terry MB, Gammon MD, Zhang FF, Teitelbaum SL, Eng SM, Sagiv SK, Gaudet MM, Neugut Al, Santella RM. OGG1 polymorphisms and breast cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Apr;15(4):811-5. PubMed PMID: 16614128.
45. Shen J, Gammon MD, Terry MB, et al. Polymorphisms in XRCC1 modify the association between polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, dietary antioxidants, and breast cancer risk. Cancer Epidemiol Biomarkers Prev 2005; 14: 336-42.
46. Shen J, Terry MB, Gammon MD, et al. MGMT genotype modulates the associations between cigarette smoking, dietary antioxidants and breast cancer risk. Carcinogenesis 2005; 26: 2131-7.
47. Cai KQ, Albarracin C, Rosen D, et al. Microsatellite instability and alteration of the expression of hMLH1 and hMSH2 in ovarian clear cell carcinoma. Hum Pathol 2004; 35: 552-9.
48. Boiteux S, Radicella JP,. Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress. Biochimie. 1999; 81: 59-67.
49. Mechanic LE, Millikan RC, Player J, et al. Polymorphisms in nucleotide excision repair genes, smoking and breast cancer in african americans and whites: a population-based case-control study. Carcinogenesis 2006; 27: 1377-85.
50. Smith TR, Levine EA, Perrier ND, et al. DNA-repair genetic polymorphisms and breast cancer risk. Cancer Epidemiol Biomarkers Prev 2003; 12 (11, Part 1): 1200-4.
51. Shen J, Desai M, Agrawal M, et al. Polymorphisms in nucleotide excision repair genes and DNA repair capacity phenotype in sisters discordant for breast cancer. Cancer Epidemiol Biomarkers Prev 2006; 15: 1614-9.