-
1
-
-
0027433553
-
Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
-
M.F. Beal, E. Brouillet, B.G. Jenkins, R.J. Ferrante, N.W. Kowall, J.M. Miller, E. Storey, R. Srivastava, B.R. Rosen, and B.T. Hyman Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid J. Neurosci. 13 1993 4181 4192
-
(1993)
J. Neurosci.
, vol.13
, pp. 4181-4192
-
-
Beal, M.F.1
Brouillet, E.2
Jenkins, B.G.3
Ferrante, R.J.4
Kowall, N.W.5
Miller, J.M.6
Storey, E.7
Srivastava, R.8
Rosen, B.R.9
Hyman, B.T.10
-
2
-
-
0037775906
-
Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: Implications for Huntington's disease
-
N. Bizat, J.M. Hermel, F. Boyer, C. Jacquard, C. Creminon, S. Ouary, C. Escartin, P. Hantraye, S. Kajewski, and E. Brouillet Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease J. Neurosci. 23 2003 5020 5030
-
(2003)
J. Neurosci.
, vol.23
, pp. 5020-5030
-
-
Bizat, N.1
Hermel, J.M.2
Boyer, F.3
Jacquard, C.4
Creminon, C.5
Ouary, S.6
Escartin, C.7
Hantraye, P.8
Kajewski, S.9
Brouillet, E.10
-
3
-
-
0037025058
-
The mechanisms of neuronal death produced by mitochondrial toxin 3-nitropropionic acid: The roles of N-methyl-D-aspartate glutamate receptors and mitochondrial calcium overload
-
W.T. Lee, H.S. Yin, and Y.Z. Shen The mechanisms of neuronal death produced by mitochondrial toxin 3-nitropropionic acid: the roles of N-methyl-D-aspartate glutamate receptors and mitochondrial calcium overload Neuroscience 112 2002 707 716
-
(2002)
Neuroscience
, vol.112
, pp. 707-716
-
-
Lee, W.T.1
Yin, H.S.2
Shen, Y.Z.3
-
4
-
-
9644265271
-
FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures
-
S. Almeida, A. Domingues, L. Rodrigues, C.R. Oliveira, and A.C. Rego FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures Neurobiol. Dis. 17 2004 435 444
-
(2004)
Neurobiol. Dis.
, vol.17
, pp. 435-444
-
-
Almeida, S.1
Domingues, A.2
Rodrigues, L.3
Oliveira, C.R.4
Rego, A.C.5
-
5
-
-
68149169019
-
BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons
-
S. Almeida, M. Laco, T. Cunha-Oliveira, C.R. Oliveira, and A.C. Rego BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons Neurobiol. Dis. 35 2009 448 456
-
(2009)
Neurobiol. Dis.
, vol.35
, pp. 448-456
-
-
Almeida, S.1
Laco, M.2
Cunha-Oliveira, T.3
Oliveira, C.R.4
Rego, A.C.5
-
6
-
-
77956142985
-
Possible nitric oxide modulation in protective effect of FK-506 against 3-nitropropionic acid-induced behavioral, oxidative, neurochemical, and mitochondrial alterations in rat brain
-
P. Kumar, H. Kalonia, and A. Kumar Possible nitric oxide modulation in protective effect of FK-506 against 3-nitropropionic acid-induced behavioral, oxidative, neurochemical, and mitochondrial alterations in rat brain Drug Chem. Toxicol. 33 2010 377 392
-
(2010)
Drug Chem. Toxicol.
, vol.33
, pp. 377-392
-
-
Kumar, P.1
Kalonia, H.2
Kumar, A.3
-
7
-
-
0035116104
-
Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum
-
G.W. Kim, and P.H. Chan Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum Neurobiol. Dis. 8 2001 114 126
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 114-126
-
-
Kim, G.W.1
Chan, P.H.2
-
8
-
-
3142514196
-
Oxidative stress in neurodegeneration: Cause or consequence?
-
J.K. Andersen Oxidative stress in neurodegeneration: cause or consequence? Nat. Med. 10 Suppl 2004 S18 25
-
(2004)
Nat. Med.
, vol.10
, Issue.SUPPL.
, pp. 18-25
-
-
Andersen, J.K.1
-
9
-
-
34250665401
-
Apoptosis signal-regulating kinase 1 in amyloid beta peptide-induced cerebral endothelial cell apoptosis
-
M.J. Hsu, C.Y. Hsu, B.C. Chen, M.C. Chen, G. Ou, and C.H. Lin Apoptosis signal-regulating kinase 1 in amyloid beta peptide-induced cerebral endothelial cell apoptosis J. Neurosci. 27 2007 5719 5729
-
(2007)
J. Neurosci.
, vol.27
, pp. 5719-5729
-
-
Hsu, M.J.1
Hsu, C.Y.2
Chen, B.C.3
Chen, M.C.4
Ou, G.5
Lin, C.H.6
-
10
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
H. Ichijo, E. Nishida, K. Irie, P. ten Dijke, M. Saitoh, T. Moriguchi, M. Takagi, K. Matsumoto, K. Miyazono, and Y. Gotoh Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways Science 275 1997 90 94
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
Takagi, M.7
Matsumoto, K.8
Miyazono, K.9
Gotoh, Y.10
-
11
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
M. Saitoh, H. Nishitoh, M. Fujii, K. Takeda, K. Tobiume, Y. Sawada, M. Kawabata, K. Miyazono, and H. Ichijo Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1 EMBO J. 17 1998 2596 2606
-
(1998)
EMBO J.
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
12
-
-
0035065836
-
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
-
K. Tobiume, A. Matsuzawa, T. Takahashi, H. Nishitoh, K. Morita, K. Takeda, O. Minowa, K. Miyazono, T. Noda, and H. Ichijo ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis EMBO Rep. 2 2001 222 228
-
(2001)
EMBO Rep.
, vol.2
, pp. 222-228
-
-
Tobiume, K.1
Matsuzawa, A.2
Takahashi, T.3
Nishitoh, H.4
Morita, K.5
Takeda, K.6
Minowa, O.7
Miyazono, K.8
Noda, T.9
Ichijo, H.10
-
13
-
-
42449161835
-
ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease
-
L. Arning, D. Monte, W. Hansen, S. Wieczorek, P. Jagiello, D.A. Akkad, J. Andrich, P.H. Kraus, C. Saft, and J.T. Epplen ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease J. Mol. Med. 86 2008 485 490
-
(2008)
J. Mol. Med.
, vol.86
, pp. 485-490
-
-
Arning, L.1
Monte, D.2
Hansen, W.3
Wieczorek, S.4
Jagiello, P.5
Akkad, D.A.6
Andrich, J.7
Kraus, P.H.8
Saft, C.9
Epplen, J.T.10
-
14
-
-
33646190885
-
The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases
-
Y. Sekine, K. Takeda, and H. Ichijo The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases Curr. Mol. Med. 6 2006 87 97
-
(2006)
Curr. Mol. Med.
, vol.6
, pp. 87-97
-
-
Sekine, Y.1
Takeda, K.2
Ichijo, H.3
-
15
-
-
5444229092
-
Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation
-
J.H. Fox, D.S. Barber, B. Singh, B. Zucker, M.K. Swindell, F. Norflus, R. Buzescu, R. Chopra, R.J. Ferrante, A. Kazantsev, and S.M. Hersch Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation J. Neurochem. 91 2004 413 422
-
(2004)
J. Neurochem.
, vol.91
, pp. 413-422
-
-
Fox, J.H.1
Barber, D.S.2
Singh, B.3
Zucker, B.4
Swindell, M.K.5
Norflus, F.6
Buzescu, R.7
Chopra, R.8
Ferrante, R.J.9
Kazantsev, A.10
Hersch, S.M.11
-
16
-
-
76249091683
-
Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease
-
K.J. Cho, B.I. Lee, S.Y. Cheon, H.W. Kim, H.J. Kim, and G.W. Kim Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease Neuroscience 2009 1128 1134
-
(2009)
Neuroscience
, pp. 1128-1134
-
-
Cho, K.J.1
Lee, B.I.2
Cheon, S.Y.3
Kim, H.W.4
Kim, H.J.5
Kim, G.W.6
-
17
-
-
0036304614
-
Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid
-
G.W. Kim, and P.H. Chan Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid J. Cereb. Blood Flow Metab. 22 2002 798 809
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 798-809
-
-
Kim, G.W.1
Chan, P.H.2
-
18
-
-
33646382411
-
Minocycline inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in mice
-
K. Heo, Y.J. Cho, K.J. Cho, H.W. Kim, H.J. Kim, H.Y. Shin, B.I. Lee, and G.W. Kim Minocycline inhibits caspase-dependent and -independent cell death pathways and is neuroprotective against hippocampal damage after treatment with kainic acid in mice Neurosci. Lett. 398 2006 195 200
-
(2006)
Neurosci. Lett.
, vol.398
, pp. 195-200
-
-
Heo, K.1
Cho, Y.J.2
Cho, K.J.3
Kim, H.W.4
Kim, H.J.5
Shin, H.Y.6
Lee, B.I.7
Kim, G.W.8
-
19
-
-
0032851595
-
Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization
-
A. Sawa, G.W. Wiegand, J. Cooper, R.L. Margolis, A.H. Sharp, J.F. Lawler Jr., J.T. Greenamyre, S.H. Snyder, and C.A. Ross Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization Nat. Med. 5 1999 1194 1198
-
(1999)
Nat. Med.
, vol.5
, pp. 1194-1198
-
-
Sawa, A.1
Wiegand, G.W.2
Cooper, J.3
Margolis, R.L.4
Sharp, A.H.5
Lawler, Jr.J.F.6
Greenamyre, J.T.7
Snyder, S.H.8
Ross, C.A.9
-
20
-
-
0037150687
-
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease
-
A.W. Dunah, H. Jeong, A. Griffin, Y.M. Kim, D.G. Standaert, S.M. Hersch, M.M. Mouradian, A.B. Young, N. Tanese, and D. Krainc Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease Science 296 2002 2238 2243
-
(2002)
Science
, vol.296
, pp. 2238-2243
-
-
Dunah, A.W.1
Jeong, H.2
Griffin, A.3
Kim, Y.M.4
Standaert, D.G.5
Hersch, S.M.6
Mouradian, M.M.7
Young, A.B.8
Tanese, N.9
Krainc, D.10
-
21
-
-
0022519244
-
Uptake and accumulation of the vital dye hydroethidine in neoplastic cells
-
C. Bucana, I. Saiki, and R. Nayar Uptake and accumulation of the vital dye hydroethidine in neoplastic cells J. Histochem. Cytochem. 34 1986 1109 1115
-
(1986)
J. Histochem. Cytochem.
, vol.34
, pp. 1109-1115
-
-
Bucana, C.1
Saiki, I.2
Nayar, R.3
-
22
-
-
0034915234
-
Comparative analysis of superoxide dismutase activity between acute pharmacological models and a transgenic mouse model of Huntington's disease
-
A. Santamaria, F. Perez-Severiano, E. Rodriguez-Martinez, P.D. Maldonado, J. Pedraza-Chaverri, C. Rios, and J. Segovia Comparative analysis of superoxide dismutase activity between acute pharmacological models and a transgenic mouse model of Huntington's disease Neurochem. Res. 26 2001 419 424
-
(2001)
Neurochem. Res.
, vol.26
, pp. 419-424
-
-
Santamaria, A.1
Perez-Severiano, F.2
Rodriguez-Martinez, E.3
Maldonado, P.D.4
Pedraza-Chaverri, J.5
Rios, C.6
Segovia, J.7
-
23
-
-
0141869839
-
Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: Role of matrix metalloproteinase-9 in early blood-brain barrier disruption?
-
G.W. Kim, Y. Gasche, S. Grzeschik, J.C. Copin, C.M. Maier, and P.H. Chan Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: role of matrix metalloproteinase-9 in early blood-brain barrier disruption? J. Neurosci. 23 2003 8733 8742
-
(2003)
J. Neurosci.
, vol.23
, pp. 8733-8742
-
-
Kim, G.W.1
Gasche, Y.2
Grzeschik, S.3
Copin, J.C.4
Maier, C.M.5
Chan, P.H.6
-
24
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
M.T. Lin, and M.F. Beal Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases Nature 443 2006 787 795
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
25
-
-
44849124411
-
ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
-
H. Nishitoh, H. Kadowaki, A. Nagai, T. Maruyama, T. Yokota, H. Fukutomi, T. Noguchi, A. Matsuzawa, K. Takeda, and H. Ichijo ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1 Genes Dev. 22 2008 1451 1464
-
(2008)
Genes Dev.
, vol.22
, pp. 1451-1464
-
-
Nishitoh, H.1
Kadowaki, H.2
Nagai, A.3
Maruyama, T.4
Yokota, T.5
Fukutomi, H.6
Noguchi, T.7
Matsuzawa, A.8
Takeda, K.9
Ichijo, H.10
-
26
-
-
44449137435
-
Antioxidants cannot suppress the lethal phenotype of a Drosophila melanogaster model of Huntington's disease
-
S. Bahadorani, and A.J. Hilliker Antioxidants cannot suppress the lethal phenotype of a Drosophila melanogaster model of Huntington's disease Genome 51 2008 392 395
-
(2008)
Genome
, vol.51
, pp. 392-395
-
-
Bahadorani, S.1
Hilliker, A.J.2
|