The promises of stem cells: Stem cell therapy for movement disorders

Parkinsonism and Related Disorders

Volumn 20, Issue SUPPL.1, 2014, Pages

  Mochizuki, Hideki ^a   Choong, Chi Jing ^a   Yasuda, Toru ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Induced pluripotent stem cell; Movement disorders; Parkinson's disease; Stem cell

Indexed keywords

ARTICLE; DISEASE SEVERITY; EMBRYONIC STEM CELL; HUMAN; HUNTINGTON CHOREA; MOTOR DYSFUNCTION; NERVE CELL LESION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REGENERATIVE MEDICINE; SHY DRAGER SYNDROME; STEM CELL; STEM CELL RESEARCH; STEM CELL TRANSPLANTATION; SUBSTANTIA NIGRA; THERAPY EFFECT; TREATMENT RESPONSE;

INDUCED PLURIPOTENT STEM CELL; MOVEMENT DISORDERS; PARKINSON'S DISEASE; STEM CELL;

ANIMALS; HUMANS; MOVEMENT DISORDERS; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 84887967879     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/S1353-8020(13)70031-2     Document Type: Article

References (24)

1. Greene PE, Fahn S Status of fetal tissue transplantation for the treatment of advanced Parkinson disease. Neurosurg Focus 2002, 13:e3.
2. Bjorklund LM, Sánchez-Pernaute R, Chung S, Andersson T, Chen IY, McNaught KS, et al. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci USA 2002, 99:2344-2349.
3. Kriks S, Shim JW, Piao J, Ganat YM, Wakeman DR, Xie Z, et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 2011, 480:547-551.
4. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
5. Park IH, Arora N, Huo H, Maherali N, Ahfeldt T, Shimamura A, et al. Disease-specific induced pluripotent stem cells. Cell 2008, 134:877-886.
6. Byers B, Cord B, Nguyen HN, Schüle B, Fenno L, Lee PC, et al. SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress. PLoS One 2011, 6:e26159.
7. Devine MJ, Ryten M, Vodicka P, Thomson AJ, Burdon T, Houlden H, et al. Parkinson's disease induced pluripotent stem cells with triplication of the a-synuclein locus. Nat Commun 2011, 2:440.
8. Imaizumi Y, Okada Y, Akamatsu W, Koike M, Kuzumaki N, Hayakawa H, et al. Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue. Mol Brain 2012, 5:35.
9. Seibler P, Graziotto J, Jeong H, Simunovic F, Klein C, Krainc D Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells. J Neurosci 2011, 31:5970-5976.
10. Nguyen HN, Byers B, Cord B, Shcheglovitov A, Byrne J, Gujar P, et al. LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell 2011, 8:267-280.
11. Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F, et al. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci U S A 2008, 105:5856-5861.
12. Kikuchi T, Morizane A, Doi D, Onoe H, Hayashi T, Kawasaki T, et al. Survival of human induced pluripotent stem cell-derived midbrain dopaminergic neurons in the brain of a primate model of Parkinson's disease. J Parkinsons Dis 2011, 1:395-412.
13. Ring KL, Tong LM, Balestra ME, Javier R, Andrews-Zwilling Y, Li G, et al. Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor. Cell Stem Cell 2012, 11:100-109.
14. Venkataramana NK, Kumar SK, Balaraju S, Radhakrishnan RC, Bansal A, Dixit A, et al. Open-labeled study of unilateral autologous bone-marrow-derived mesenchymal stem cell transplantation in Parkinson's disease. Transl Res 2010, 155:62-70.
15. Venkataramana NK, Pal R, Rao SA, Naik AL, Jan M, Nair R, et al. Bilateral transplantation of allogenic adult human bone marrow-derived mesenchymal stem cells into the subventricular zone of Parkinson's disease: a pilot clinical study. Stem Cells Int 2012, 2012:931902.
16. Lee PH, Kim JW, Bang OY, Ahn YH, Joo IS, Huh K Autologous mesenchymal stem cell therapy delays the progression of neurological deficits in patients with multiple system atrophy. Clin Pharmacol Ther 2008, 83:723-730.
17. Höglinger GU, Rizk P, Muriel MP, Duyckaerts C, Oertel WH, Caille I, et al. Dopamine depletion impairs precursor cell proliferation in Parkinson disease. Nat Neurosci 2004, 7:726-735.
18. Yoshimi K, Ren YR, Seki T, Yamada M, Ooizumi H, Onodera M, et al. Possibility for neurogenesis in substantia nigra of parkinsonian brain. Ann Neurol 2005, 58:31-40.
19. Aubry L, Bugi A, Lefort N, Rousseau F, Peschanski M, Perrier AL Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats. Proc Natl Acad Sci U S A 2008, 105:16707-16712.
20. HD iPSC Consortium Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes. Cell Stem Cell 2012, 11:264-278.
21. An MC, Zhang N, Scott G, Montoro D, Wittkop T, Mooney S, et al. Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells. Cell Stem Cell 2012, 11:253-263.
22. Curtis MA, Penney EB, Pearson AG, van Roon-Mom WM, Butterworth NJ, Dragunow M, et al. Increased cell proliferation and neurogenesis in the adult human Huntington's disease brain. Proc Natl Acad Sci U S A 2003, 100:9023-9027.
23. Cho SR, Benraiss A, Chmielnicki E, Samdani A, Economides A, Goldman SA Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington disease. J Clin Invest 2007, 117:2889-2902.
24. Onodera M Gene and cell therapy for relapsed leukemia after allo-stem cell transplantation. Front Biosci 2008, 13:3408-3414.