Glucokinase activator: Practical asymmetric hydrogenation and scalable synthesis of an API fragment

Organic Process Research and Development

Volumn 17, Issue 11, 2013, Pages 1451-1457

  Bachmann, Stephan ^a   Fettes, Alec ^a   Lautz, Christian ^b   Scalone, Michelangelo ^a  

^a PRED Hoffmann La Roche   (Switzerland)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ASYMMETRIC HYDROGENATION; CATALYST LOADINGS; DICYCLOHEXYLAMINE; ENANTIOMERIC EXCESS; ENANTIOSELECTIVE SYNTHESIS; PERKIN REACTIONS; RUTHENIUM CATALYSTS; SCALABLE SYNTHESIS;

CATALYSTS;

HYDROGENATION;

EID: 84887892002     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op4002164     Document Type: Article

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