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For reviews of Click Chemistry, see a
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Examples of achiral ferrocenyl 1,2,3-triazoles: (a) Casas-Solvas, J. M.; Vergas-Berenguel, A.; Capitán-Valley, L. F.; Francisco, S.-G. Org. Lett. 2004, 6, 3687-3690.
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Examples of achiral ferrocenyl 1,2,3-triazoles: (a) Casas-Solvas, J. M.; Vergas-Berenguel, A.; Capitán-Valley, L. F.; Francisco, S.-G. Org. Lett. 2004, 6, 3687-3690.
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The ferrocenyl amine 1 can be prepared on a large scale (20g scale) by resolution of the racemate. Gokel, G. W.; Ugi, I. K. J. Am. Chem. Soc. 1972, 49, 294-296.
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The ferrocenyl amine 1 can be prepared on a large scale (20g scale) by resolution of the racemate. Gokel, G. W.; Ugi, I. K. J. Am. Chem. Soc. 1972, 49, 294-296.
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Asymmetric Hydrogenation
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For reviews of Rh-catalyzed asymmetric hydrogenation, see: a, 2nd ed, Ojima, I, Ed, Wiley-VCH: New York
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For reviews of Rh-catalyzed asymmetric hydrogenation, see: (a) Ohkuma, T.; Kitamura. M.; Noyori, R. Asymmetric Hydrogenation. In Catalytic Asymmetric Synthesis, 2nd ed.; Ojima, I., Ed.; Wiley-VCH: New York, 2000;pp 1-110.
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38349190963
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The enantiomer of 5a was prepared from enantiomer of 1 by the same procedure as shown in Scheme 1.
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The enantiomer of 5a was prepared from enantiomer of 1 by the same procedure as shown in Scheme 1.
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20
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0033517686
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(a) Ireland, T.; Grossheimann, G.; Wieser-Jeunesse, C.; Knochel, P. Angew. Chem., Int. Ed. 1999, 38, 3212-3214.
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Hydrogenation of Carbonyl Groups
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For reviews of Ru-catalyzed asymmetric hydrogenation, see: a, Jacobsen, E. N, Pfalz, A, Yamamoto, H, Eds, Springer: Berlin
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For reviews of Ru-catalyzed asymmetric hydrogenation, see: (a) Ohkuma, T.; Noyori, R. Hydrogenation of Carbonyl Groups. In Comprehensive Asymmetric Synthesis; Jacobsen, E. N., Pfalz, A., Yamamoto, H., Eds.; Springer: Berlin, 2000; Vol. 1, pp 199-246.
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Hydrogenation and Transfer Hydrogenation
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Murahashi, S.-i, Ed, Wiley-VCH: Weinheim
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For reviews of asymmetric allylic substitution, see: a, Springer: Berlin
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0029928380
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The chiral pyrazole ferrocenylphosphine ligands, which are similar to 6 and 8, have been applied to the asymmetric allylic substitutions, (a) Togni, A.; Burckhart, Urs.; Gramlich, V.; Pregosin, P. S.; Salzmann, R. J. Am. Chem. Soc. 1996, 118, 1031-1047.
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The chiral pyrazole ferrocenylphosphine ligands, which are similar to 6 and 8, have been applied to the asymmetric allylic substitutions, (a) Togni, A.; Burckhart, Urs.; Gramlich, V.; Pregosin, P. S.; Salzmann, R. J. Am. Chem. Soc. 1996, 118, 1031-1047.
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14544285465
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For recent examples of efficient chiral ferrocenylphosphine ligands in asymmetric hydrogenations, see: a
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For recent examples of efficient chiral ferrocenylphosphine ligands in asymmetric hydrogenations, see: (a) Boaz, N. W.; Mackenzie, E. B.; Debenham, S. D.; Large, S. E.; Ponasik, J.; James, A. J. Org. Chem. 2005, 70, 1872-1880.
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