-
1
-
-
42149124403
-
Targeting melanocortin receptors: An approach to treat weight disorders and sexual dysfunction
-
J.E.S. Wikberg, and F. Mutulis Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction Nat. Rev. Drug Discov. 7 2008 307 323
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 307-323
-
-
Wikberg, J.E.S.1
Mutulis, F.2
-
2
-
-
78651175536
-
The uptake of atropine and related drugs by intestinal smooth muscle of the guinea-pig in relation to acetylcholine receptors
-
W.D. Paton, and H.P. Rang The uptake of atropine and related drugs by intestinal smooth muscle of the guinea-pig in relation to acetylcholine receptors Proc. R. Soc. Lond. [Biol.] 163 1965 1 44
-
(1965)
Proc. R. Soc. Lond. [Biol.]
, vol.163
, pp. 1-44
-
-
Paton, W.D.1
Rang, H.P.2
-
3
-
-
84865518493
-
An update of novel screening methods for GPCR in drug discovery
-
L. Chen, L. Jin, and N. Zhou An update of novel screening methods for GPCR in drug discovery Expert Opin. Drug Discov. 7 2012 791 806
-
(2012)
Expert Opin. Drug Discov.
, vol.7
, pp. 791-806
-
-
Chen, L.1
Jin, L.2
Zhou, N.3
-
4
-
-
78650630819
-
Fluorescence polarization assays in small molecule screening
-
W.A. Lea, and A. Simeonov Fluorescence polarization assays in small molecule screening Expert Opin. Drug Discov. 6 2010 17 32
-
(2010)
Expert Opin. Drug Discov.
, vol.6
, pp. 17-32
-
-
Lea, W.A.1
Simeonov, A.2
-
5
-
-
77954499978
-
A fluorescence anisotropy assay for the muscarinic M1 G-protein-coupled receptor
-
K.G. Huwiler, T. De Rosier, B. Hanson, and K.W. Vogel A fluorescence anisotropy assay for the muscarinic M1 G-protein-coupled receptor Assay Drug Dev. Technol. 8 2010 356 366
-
(2010)
Assay Drug Dev. Technol.
, vol.8
, pp. 356-366
-
-
Huwiler, K.G.1
De Rosier, T.2
Hanson, B.3
Vogel, K.W.4
-
6
-
-
1842775922
-
Miniaturization of fluorescence polarization receptor-binding assays using CyDye-labeled ligands
-
A. Harris, S. Cox, D. Burns, and C. Norey Miniaturization of fluorescence polarization receptor-binding assays using CyDye-labeled ligands J. Biomol. Screen. 8 2003 410 420
-
(2003)
J. Biomol. Screen.
, vol.8
, pp. 410-420
-
-
Harris, A.1
Cox, S.2
Burns, D.3
Norey, C.4
-
7
-
-
65449154751
-
Design, synthesis, and pharmacology of fluorescently labeled analogs of serotonin: Application to screening of the 5-HT2C receptor
-
P. Cornelius, E. Lee, W. Lin, R. Wang, W. Werner, J.A. Brown, F. Stuhmeier, J.G. Boyd, and K. McClure Design, synthesis, and pharmacology of fluorescently labeled analogs of serotonin: application to screening of the 5-HT2C receptor J. Biomol. Screen. 14 2009 360 370
-
(2009)
J. Biomol. Screen.
, vol.14
, pp. 360-370
-
-
Cornelius, P.1
Lee, E.2
Lin, W.3
Wang, R.4
Werner, W.5
Brown, J.A.6
Stuhmeier, F.7
Boyd, J.G.8
McClure, K.9
-
8
-
-
33646029969
-
Melanocortin 4 receptors interact with antimicrobial frog peptide analogues
-
E.U. Do, E.B. Jo, G. Choi, L.Z. Piao, J. Shin, M.D. Seo, S.J. Kang, B.J. Lee, K.H. Kim, J.B. Kim, and S.I. Kim Melanocortin 4 receptors interact with antimicrobial frog peptide analogues Biochem. Biophys. Res. Commun. 343 2006 1094 1100
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.343
, pp. 1094-1100
-
-
Do, E.U.1
Jo, E.B.2
Choi, G.3
Piao, L.Z.4
Shin, J.5
Seo, M.D.6
Kang, S.J.7
Lee, B.J.8
Kim, K.H.9
Kim, J.B.10
Kim, S.I.11
-
9
-
-
0035964187
-
Real-time kinetics of ligand/cell surface receptor interactions in living cells: Binding of epidermal growth factor to the epidermal growth factor receptor
-
DOI 10.1021/bi010705t
-
J.C. Wilkinson, R.A. Stein, C.A. Guyer, J.M. Beechem, and J.V. Staros Real-time kinetics of ligand/cell surface receptor interactions in living cells: binding of epidermal growth factor to the epidermal growth factor receptor Biochemistry 40 2001 10230 10242 (Pubitemid 32800130)
-
(2001)
Biochemistry
, vol.40
, Issue.34
, pp. 10230-10242
-
-
Wilkinson, J.C.1
Stein, R.A.2
Guyer, C.A.3
Beechem, J.M.4
Staros, J.V.5
-
10
-
-
44849096225
-
Cell-free assay of G-protein-coupled receptors using fluorescence polarization
-
DOI 10.1177/1087057108318332
-
J.W. Jones, T.A. Greene, C.A. Grygon, B.J. Doranz, and M.P. Brown Cell-free assay of G-protein-coupled receptors using fluorescence polarization J. Biomol. Screen. 13 2008 424 429 (Pubitemid 351793990)
-
(2008)
Journal of Biomolecular Screening
, vol.13
, Issue.5
, pp. 424-429
-
-
Jones, J.W.1
Greene, T.A.2
Grygon, C.A.3
Doranz, B.J.4
Brown, M.P.5
-
11
-
-
77952744237
-
Fluorescence anisotropy assay for pharmacological characterization of ligand binding dynamics to melanocortin 4 receptors
-
S. Veiksina, S. Kopanchuk, and A. Rinken Fluorescence anisotropy assay for pharmacological characterization of ligand binding dynamics to melanocortin 4 receptors Anal. Biochem. 402 2010 32 39
-
(2010)
Anal. Biochem.
, vol.402
, pp. 32-39
-
-
Veiksina, S.1
Kopanchuk, S.2
Rinken, A.3
-
12
-
-
0030700766
-
2-adrenergic receptors from extracellular baculovirus particles
-
T.P. Loisel, H. Ansanay, S. St-Onge, B. Gay, P. Boulanger, A.D. Strosberg, S. Marullo, and M. Bouvier Recovery of homogeneous and functional [beta]2-adrenergic receptors from extracellular baculovirus particles Nat. Biotechnol. 15 1997 1300 1304 (Pubitemid 27465144)
-
(1997)
Nature Biotechnology
, vol.15
, Issue.12
, pp. 1300-1304
-
-
Loisel, T.P.1
Ansanay, H.2
St-Onge, S.3
Gay, B.4
Boulanger, P.5
Donny Strosberg, A.6
Marullo, S.7
Bouvier, M.8
-
13
-
-
40449084755
-
The baculovirus display technology - An evolving instrument for molecular screening and drug delivery
-
DOI 10.2174/138620708783744525
-
A.R. Makela, and C. Oker-Blom The baculovirus display technology - an evolving instrument for molecular screening and drug delivery Comb. Chem. High Throughput Screen. 11 2008 86 98 (Pubitemid 351347213)
-
(2008)
Combinatorial Chemistry and High Throughput Screening
, vol.11
, Issue.2
, pp. 86-98
-
-
Makela, A.R.1
Oker-Blom, C.2
-
14
-
-
32344437690
-
A rapid method for estimation of baculovirus titer based on viable cell size
-
DOI 10.1016/j.jviromet.2005.08.021, PII S0166093405002867
-
V. Janakiraman, W.F. Forrest, B. Chow, and S. Seshagiri A rapid method for estimation of baculovirus titer based on viable cell size J. Virol. Methods 132 2006 48 58 (Pubitemid 43220161)
-
(2006)
Journal of Virological Methods
, vol.132
, Issue.1-2
, pp. 48-58
-
-
Janakiraman, V.1
Forrest, W.F.2
Chow, B.3
Seshagiri, S.4
-
15
-
-
0036143097
-
Fluorescence polarization standards for high-throughput screening and imaging
-
R.B. Thompson, I. Gryczynski, and J. Malicka Fluorescence polarization standards for high-throughput screening and imaging Biotechniques 32 2002 34 42 (Pubitemid 34052746)
-
(2002)
BioTechniques
, vol.32
, Issue.1
, pp. 34-42
-
-
Thompson, R.B.1
Gryczynski, I.2
Malicka, J.3
-
16
-
-
0242492158
-
A non-peptide radioiodinated high affinity melanocortin-4 receptor ligand
-
DOI 10.1002/jlcr.735
-
F. Mutulis, S. Yahorava, I. Mutule, A. Yahorau, S. Kopanchuk, S. Veiksina, A. Rinken, and J.E.S. Wikberg A non-peptide radioiodinated high affinity melanocortin-4 receptor ligand J. Label. Compd. Radiopharm. 46 2003 1007 1017 (Pubitemid 37433114)
-
(2003)
Journal of Labelled Compounds and Radiopharmaceuticals
, vol.46
, Issue.11
, pp. 1007-1017
-
-
Mutulis, F.1
Yahorava, S.2
Mutule, I.3
Yahorau, A.4
Kopanchuk, S.5
Veiksina, S.6
Rinken, A.7
Wikberg, J.E.S.8
-
18
-
-
21344433863
-
Fluorescence polarization/anisotropy approaches to study protein-ligand interactions: Effects of errors and uncertainties
-
D.M. Jameson, and G. Mocz Fluorescence polarization/anisotropy approaches to study protein-ligand interactions: effects of errors and uncertainties Methods Mol. Biol. 305 2005 301 322
-
(2005)
Methods Mol. Biol.
, vol.305
, pp. 301-322
-
-
Jameson, D.M.1
Mocz, G.2
-
19
-
-
33751557793
-
A simple theoretical model for fluorescence polarization binding assay development
-
DOI 10.1177/1087057106294841
-
O. Nosjean, S. Souchaud, C. Deniau, O. Geneste, N. Cauquil, and J.A. Boutin A simple theoretical model for fluorescence polarization binding assay development J. Biomol. Screen. 11 2006 949 958 (Pubitemid 44847149)
-
(2006)
Journal of Biomolecular Screening
, vol.11
, Issue.8
, pp. 949-958
-
-
Nosjean, O.1
Souchaud, S.2
Deniau, C.3
Geneste, O.4
Cauquil, N.5
Boutin, J.A.6
-
20
-
-
21844437963
-
The study of bimolecular reactions under non-pseudo-first order conditions
-
DOI 10.1016/j.bpc.2005.04.006, PII S0301462205000864
-
F. Malatesta The study of bimolecular reactions under non-pseudo-first order conditions Biophys. Chem. 116 2005 251 256 (Pubitemid 40962453)
-
(2005)
Biophysical Chemistry
, vol.116
, Issue.3
, pp. 251-256
-
-
Malatesta, F.1
-
22
-
-
11144265736
-
A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein-protein interactions by fluorescence polarization
-
DOI 10.1021/bi048233g
-
M.H. Roehrl, J.Y. Wang, and G. Wagner A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein-protein interactions by fluorescence polarization Biochemistry 43 2004 16056 16066 (Pubitemid 40041019)
-
(2004)
Biochemistry
, vol.43
, Issue.51
, pp. 16056-16066
-
-
Roehrl, M.H.A.1
Wang, J.Y.2
Wagner, G.3
-
23
-
-
0028936571
-
An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule
-
Z.X. Wang An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule FEBS Lett. 360 1995 111 114
-
(1995)
FEBS Lett.
, vol.360
, pp. 111-114
-
-
Wang, Z.X.1
-
24
-
-
65349148442
-
G-protein coupled receptor array technologies: Site directed immobilisation of liposomes containing the H1-histamine or M2-muscarinic receptors
-
K. Bailey, M. Bally, W. Leifert, J. Voros, and T. McMurchie G-protein coupled receptor array technologies: site directed immobilisation of liposomes containing the H1-histamine or M2-muscarinic receptors Proteomics 9 2009 2052 2063
-
(2009)
Proteomics
, vol.9
, pp. 2052-2063
-
-
Bailey, K.1
Bally, M.2
Leifert, W.3
Voros, J.4
McMurchie, T.5
-
25
-
-
0041903675
-
4 receptor
-
DOI 10.1074/jbc.M302801200
-
K. Masuda, H. Itoh, T. Sakihama, C. Akiyama, K. Takahashi, R. Fukuda, T. Yokomizo, T. Shimizu, T. Kodama, and T. Hamakubo A combinatorial G protein-coupled receptor reconstitution system on budded baculovirus. Evidence for Gai and Gao coupling to a human leukotriene B4 receptor J. Biol. Chem. 278 2003 24552 24562 (Pubitemid 37548608)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.27
, pp. 24552-24562
-
-
Masuda, K.1
Itoh, H.2
Sakihama, T.3
Akiyama, C.4
Takahashi, K.5
Fukuda, R.6
Yokomizo, T.7
Shimizu, T.8
Kodama, T.9
Hamakubo, T.10
-
26
-
-
84865040308
-
BacMam system for FRET based cAMP sensor expression in studies of melanocortin MC1 receptor activation
-
O. Mazina, R. Reinart, S. Kopanchuk, and A. Rinken BacMam system for FRET based cAMP sensor expression in studies of melanocortin MC1 receptor activation J. Biomol. Screen. 17 2012 1096 1101
-
(2012)
J. Biomol. Screen.
, vol.17
, pp. 1096-1101
-
-
Mazina, O.1
Reinart, R.2
Kopanchuk, S.3
Rinken, A.4
-
27
-
-
17444407862
-
Co-operative regulation of ligand binding to melanocortin receptor subtypes: Evidence for interacting binding sites
-
DOI 10.1016/j.ejphar.2005.02.021
-
S. Kopanchuk, S. Veiksina, R. Petrovska, I. Mutule, M. Szardenings, A. Rinken, and J.E.S. Wikberg Co-operative regulation of ligand binding to melanocortin receptor subtypes: evidence for interacting binding sites Eur. J. Pharmacol. 512 2005 85 95 (Pubitemid 40544342)
-
(2005)
European Journal of Pharmacology
, vol.512
, Issue.2-3
, pp. 85-95
-
-
Kopanchuk, S.1
Veiksina, S.2
Petrovska, R.3
Mutule, I.4
Szardenings, M.5
Rinken, A.6
Wikberg, J.E.S.7
-
28
-
-
33746874856
-
Kinetic evidence for tandemly arranged ligand binding sites in melanocortin 4 receptor complexes
-
DOI 10.1016/j.neuint.2006.04.006, PII S0197018606001720
-
S. Kopanchuk, S. Veiksina, F. Mutulis, I. Mutule, S. Yahorava, I. Mandrika, R. Petrovska, A. Rinken, and J.E.S. Wikberg Kinetic evidence for tandemly arranged ligand binding sites in melanocortin 4 receptor complexes Neurochem. Int. 49 2006 533 542 (Pubitemid 44189650)
-
(2006)
Neurochemistry International
, vol.49
, Issue.5
, pp. 533-542
-
-
Kopanchuk, S.1
Veiksina, S.2
Mutulis, F.3
Mutule, I.4
Yahorava, S.5
Mandrika, I.6
Petrovska, R.7
Rinken, A.8
Wikberg, J.E.S.9
-
29
-
-
0037371579
-
Molecular determinants of melanocortin 4 receptor ligand binding and MC4/MC3 receptor selectivity
-
DOI 10.1124/jpet.102.044974
-
S.A. Nickolls, M.I. Cismowski, X. Wang, M. Wolff, P.J. Conlon, and R.A. Maki Molecular determinants of melanocortin 4 receptor ligand binding and MC4/MC3 receptor selectivity J. Pharmacol. Exp. Ther. 304 2003 1217 1227 (Pubitemid 36254435)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.304
, Issue.3
, pp. 1217-1227
-
-
Nickolls, S.A.1
Cismowski, M.I.2
Wang, X.3
Wolff, M.4
Conlon, P.J.5
Maki, R.A.6
-
30
-
-
25144474404
-
A review of melanocortin receptor small molecule ligands
-
DOI 10.1016/j.peptides.2004.11.024, PII S0196978105002202, The Melanocortin Pathway 2005
-
A. Todorovic, and C. Haskell-Luevano A review of melanocortin receptor small molecule ligands Peptides 26 2005 2026 2036 (Pubitemid 41354561)
-
(2005)
Peptides
, vol.26
, Issue.10
, pp. 2026-2036
-
-
Todorovic, A.1
Haskell-Luevano, C.2
-
31
-
-
77956840539
-
Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a 'two-step' competition binding approach
-
A. Packeu, M. Wennerberg, A. Balendran, and G. Vauquelin Estimation of the dissociation rate of unlabelled ligand-receptor complexes by a 'two-step' competition binding approach Br. J. Pharmacol. 161 2010 1311 1328
-
(2010)
Br. J. Pharmacol.
, vol.161
, pp. 1311-1328
-
-
Packeu, A.1
Wennerberg, M.2
Balendran, A.3
Vauquelin, G.4
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