Loop motions important to product expulsion in the Thermobifida fusca glycoside hydrolase family 6 cellobiohydrolase from structural and computational studies

Journal of Biological Chemistry

Volumn 288, Issue 46, 2013, Pages 33107-33117

  Wu, Miao ^a   Bu, Lintao ^b   Vuong, Thu V ^c,d   Wilson, David B ^c   Crowley, Michael F ^b   Sandgren, Mats ^a   Ståhlberg, Jerry ^a   Beckham, Gregg T ^b   Hansson, Henrik ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b NATIONAL RENEWABLE ENERGY LABORATORY   (United States)

^c Department of Obstetrics Gynecology   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMASS DEGRADATIONS; CELLOBIOHYDROLASES; CELLULOLYTIC FUNGUS; COMPUTATIONAL STUDIES; EQUAL PROBABILITY; GLYCOSIDE HYDROLASE FAMILY 6; STRUCTURAL DETAILS; THERMOBIFIDA FUSCA;

AMINO ACIDS; CELLULOSE; HYDROLYSIS;

ENZYMES;

CELLULOSE 1,4 BETA CELLOBIOSIDASE;

ARTICLE; BINDING AFFINITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME RELEASE; ENZYME SUBSTRATE; LIGAND BINDING; MATHEMATICAL ANALYSIS; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; THERMOBIFIDA FUSCA; X RAY CRYSTALLOGRAPHY;

CELLOBIOHYDROLASE; CELLULASE; ENZYME STRUCTURE; GLYCOSIDE HYDROLASES; MOLECULAR DYNAMICS; THERMOBIFIDA FUSCA; X-RAY CRYSTALLOGRAPHY;

ACTINOMYCETALES; AMINO ACID SUBSTITUTION; BACTERIAL PROTEINS; CELLOBIOSE; CELLULOSE 1,4-BETA-CELLOBIOSIDASE; MODELS, MOLECULAR; MUTATION, MISSENSE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84887846505     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.502765     Document Type: Article

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