Activated Cdc42-associated Kinase 1 (Ack1) is required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor recruitment to lipid rafts and induction of cell death

Journal of Biological Chemistry

Volumn 288, Issue 46, 2013, Pages 32922-32931

  Linderoth, Emma ^a   Pilia, Giulia ^b   Mahajan, Nupam P ^c   Ferby, Ingvar ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b SCIENCE FOR LIFE LABORATORY   (Sweden)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEATH-INDUCING SIGNALING COMPLEXES; EPITHELIAL CELLS; MEMBRANE MICRODOMAINS; PHARMACOLOGICAL INHIBITION; REGULATORY MECHANISM; TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGANDS; TYROSINE KINASE; UP-REGULATION;

AMINO ACIDS; CELL CULTURE; ENZYMES; LIGANDS;

CELL DEATH;

CASPASE 8; DEATH RECEPTOR 4; DEATH RECEPTOR 5; PROTEIN CDC42; RECEPTOR FOR ACTIVATED C KINASE 1; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CELL COMPARTMENTALIZATION; CELL DEATH; CELL FRACTIONATION; CONTROLLED STUDY; ENZYME ACTIVATION; EPITHELIUM CELL; LIPID RAFT; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; CANCER; CELL SIGNALING; LIPID RAFTS; TRAIL; TYROSINE-PROTEIN KINASE (TYROSINE KINASE);

CASPASE 8; CELL DEATH; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MEMBRANE MICRODOMAINS; PROTEIN TRANSPORT; PROTEIN-TYROSINE KINASES; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; TNF-RELATED APOPTOSIS-INDUCING LIGAND; UP-REGULATION;

EID: 84887844793     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.481507     Document Type: Article

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