Mig6 Is a Sensor of EGF Receptor Inactivation that Directly Activates c-Abl to Induce Apoptosis during Epithelial Homeostasis

Developmental Cell

Volumn 23, Issue 3, 2012, Pages 547-559

  Hopkins, Sarah ^a   Linderoth, Emma ^a   Hantschel, Oliver ^b,e   Suarez Henriques, Paula ^a   Pilia, Giulia ^c   Kendrick, Howard ^d,f   Smalley, Matthew J ^d,f   Superti Furga, Giulio ^b   Ferby, Ingvar ^a,c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^c UPPSALA UNIVERSITY   (Sweden)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^e EPFL   (Switzerland)

^f CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; ADAPTOR PROTEIN; CASPASE 3; EPIDERMAL GROWTH FACTOR RECEPTOR; MIG6 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE FYN; PROTEIN KINASE YES; PROTEIN P73; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST EPITHELIUM; CATALYSIS; CELL DIFFERENTIATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOCIATION; DNA DAMAGE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; FIBROBLAST; HOMEOSTASIS; MALE; MOLECULAR INTERACTION; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; CELLS, CULTURED; EPITHELIAL CELLS; HEK293 CELLS; HOMEOSTASIS; HUMANS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS C-ABL; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84866047004     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2012.08.001     Document Type: Article

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