Balanced globin protein expression and heme biosynthesis improve production of human hemoglobin in Saccharomyces cerevisiae

Metabolic Engineering

Volumn 21, Issue , 2014, Pages 9-16

  Liu, Lifang ^a   Martínez, José L ^a   Liu, Zihe ^a   Petranovic, Dina ^a   Nielsen, Jens ^a  

^a Chalmers University of Technology   (Denmark)

Author keywords

Heme biosynthesis; Human hemoglobin; Prosthetic group; Protein production; Saccharomyces cerevisiae

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CELL ENGINEERING; PORPHYRINS; PROSTHETICS; PROTEINS; YEAST;

BIOSYNTHESIS PATHWAYS; BIOSYNTHETIC PATHWAY; HEME BIOSYNTHESIS; NOVEL STRATEGIES; PROSTHETIC GROUPS; PROTEIN EXPRESSIONS; PROTEIN PRODUCTION; RESEARCH INTERESTS;

HEMOGLOBIN;

COPROPORPHYRIN; GLOBIN; HEMOGLOBIN; RECOMBINANT HEMOGLOBIN;

ARTICLE; BATCH FERMENTATION; BIOSYNTHESIS; CODON; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE SEQUENCE; HEMOGLOBIN DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLIC ENGINEERING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; YEAST CELL;

SACCHAROMYCES CEREVISIAE;

HEME BIOSYNTHESIS; HUMAN HEMOGLOBIN; PROSTHETIC GROUP; PROTEIN PRODUCTION; SACCHAROMYCES CEREVISIAE;

GENE EXPRESSION; GENETIC ENGINEERING; HEME; HEMOGLOBINS; HUMANS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 84887789916     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2013.10.010     Document Type: Article

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