Identification of rate-limiting steps in yeast heme biosynthesis

Biochemical and Biophysical Research Communications

Volumn 310, Issue 4, 2003, Pages 1247-1253

  Hoffman, Marta ^a   Góra, Monika ^a   Rytka, Joanna ^a  

^a INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

Author keywords

Heme; Porphyrins; Saccharomyces cerevisiae

Indexed keywords

DEAMINASE; HEME; PORPHOBILINOGEN SYNTHASE;

ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; ENZYME ACTIVITY; FUNGAL STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; STRAIN DIFFERENCE;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0141996306     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.09.151     Document Type: Article

References (37)

1. Labbe-Bois R., Labbe P. Tetrapyrrole and heme biosynthesis in the yeast Saccharomyces cerevisiae. Dailey H.A. Biosynthesis of Heme and Chlorophylls. 1990;235-286 Mc Graw-Hill, New York.
2. G.C. Ferreira (Ed.), Heme Biosynthesis: Biochemistry, Molecular Biology, and Relationship to Disease, J. Bioenerg. Biomemb. 27 (1995) 145-248.
3. Chełstowska A., Rytka J. Heme biosynthesis in the yeast Saccharomyces cerevisiae. Postpy Biochem. 39:1993;173-185.
4. Volland C., Felix F. Isolation and properties of 5-aminolevulinate synthase from the yeast Saccharomyces cerevisiae. Eur. J. Biochem. 142:1984;551-557.
5. Borralho L.M., Ortiz C.H.D., Panek A.D., Mattoon J.R. Purification of. δ -aminolevulinate dehydratase from genetically engineered yeast Yeast. 6:1990;319-330.
6. Correa Garcia S.R., Rossetti M.V., Batlle A.M. Studies on porphobilinogen deaminase from Saccharomyces cerevisiae. Z. Naturforsch. 46:1991;1017-1023.
7. Felix F., Brouillet N. Purification and properties of uroporphyrinogen decarboxylase from Saccharomyces cerevisiae. Eur. J. Biochem. 188:1990;393-403.
8. Camadro J.M., Chambon H., Jolles J., Labbe P. Purification and properties of coproporphyrinogen oxidase from the yeast Saccharomyces cerevisiae. Eur. J. Biochem. 156:1986;579-587.
9. Labbe P. Purification and properties of coproporphyrinogen III oxidase from yeast. Methods Enzymol. 281:1997;367-378.
10. Camadro J.M., Thome F., Brouillet N., Labbe P. Purification and properties of protoporphyrinogen oxidase from the yeast Saccharomyces cerevisiae. J. Biol. Chem. 269:1994;32085-32091.
11. Camadro J.M., Labbe P. Purification and properties of ferrochelatase from the yeast Saccharomyces cerevisiae. J. Biol. Chem. 263:1988;11675-11682.
12. Urban-Grimal D., Volland C., Garnier T., Dehoux P., Labbe-Bois R. The nucleotide sequence of the HEM1 gene and evidence for a precursor form of the mitochondrial 5-aminolevulinate synthase in Saccharomyces cerevisiae. Eur. J. Biochem. 156:1986;511-519.
13. Myers A.M., Crivellone M.D., Koerner T.J., Tzagoloff A. Characterization of the yeast HEM2 gene and transcriptional regulation of COX5 and COR1 by heme. J. Biol. Chem. 262:1987;16822-16829.
14. Keng T., Richard C., Larocque R. Structure and regulation of yeast HEM3, the gene for porphobilinogen deaminase. Mol. Gen. Genet. 234:1992;233-243.
15. Garey J.R., Labbe-Bois R., Chelstowska A., Rytka J., Harrison L., Kushner J., Labbe P. Uroporphyrinogen decarboxylase in Saccharomyces cerevisiae. HEM12 gene sequence and evidence for two conserved glycines essential for enzymatic activity. Eur. J. Biochem. 205:1992;1011-1016.
16. Zagorec M., Buhler J.M., Treich I., Keng T., Guarente L., Labbe-Bois R. Isolation, sequence, and regulation by oxygen of the yeast HEM13 gene coding for coproporphyrinogen oxidase. J. Biol. Chem. 263:1988;9718-9724.
17. Camadro J.M., Labbe P. Cloning and characterization of the yeast HEM14 gene coding for protoporphyrinogen oxidase, the molecular target of diphenyl ether-type herbicides. J. Biol. Chem. 271:1996;9120-9128.
18. Labbe-Bois R. The ferrochelatase from Saccharomyces cerevisiae. Sequence, disruption, and expression of its structural gene HEM15. J. Biol. Chem. 265:1990;7278-7283.
19. Labbe-Bois R., Simon M., Rytka J., Litwińska J., Biliński T. Effect of 5-aminolevulinic acid synthesis deficiency on expression of other enzymes of heme pathway in yeast. Biochem. Biophys. Res. Commun. 95:1980;1357-1363.
20. Biliński T., Litwińska J., Łukaszkiewicz J., Rytka J., Simon M., Labbe-Bois R. Characterization of two mutant strains of Saccharomyces cerevisiae deficient in coproporphyrinogen III oxidase activity. J. Gen. Microbiol. 122:1981;79-87.
21. Urban-Grimal D., Labbe-Bois R. Genetic and biochemical characterization of mutants of Saccharomyces cerevisiae blocked in six different steps of heme biosynthesis. Mol. Gen. Genet. 183:1981;85-92.
22. Camadro J.M., Urban-Grimal D., Labbe P. A new assay for protoporphyrinogen oxidase. Evidence for a total deficiency in that activity in a heme-less mutant of Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 106:1982;724-730.
23. Rytka J., Biliński T., Labbe-Bois R. Modified uroporphyrinogen decarboxylase activity in a yeast mutant which mimics porphyria cutanea tarda. Biochem. J. 218:1984;405-413.
24. Żoładek T., Nhi N.B., Rytka J. Saccharomyces cerevisiae mutants defective in heme biosynthesis as a tool for studying the mechanism of phototoxicity of porphyrins. Photochem. Photobiol. 64:1996;957-962.
25. Krawiec Z., Świeciło A., Biliński T. Heme synthesis in yeast does not require oxygen as an obligatory electron acceptor. Acta Biochim. Polon. 47:2000;1027-1035.
26. Labbe-Bois R., Volland C. Changes in the activities of the protoheme-synthesizing system during the growth of yeast under different conditions. Arch. Biochem. Biophys. 179:1977;565-577.
27. Żoładek T., Chełstowska A., Labbe-Bois R., Rytka J. Isolation and characterization of extragenic mutations affecting the expression of the uroporphyrinogen decarboxylase gene (HEM12) in Saccharomyces cerevisiae. Mol. Gen. Genet. 247:1995;471-481.
28. Rose M.D., Winston F., Hieter P. Methods in Yeast Genetics. A Laboratory Course Manual. 1990;CSH Laboratory Press.
29. Chen D.-C., Yang B.-C., Kuo T.T. One-step transformation of yeast in stationary phase. Curr. Genet. 21:1992;83-84.
30. Maniatis T., Sambrook J., Fritsch E.F. Molecular Cloning. A Laboratory Manual. 1989;CSH Laboratory Press.
31. Innis M.A., Gelfand D.H., Suinsky J.J., White T.J. PCR protocols: a guide to methods and applications. 1990;Academic Press.
32. Hill J.E., Myers A.M., Koerner T.J., Tzagoloff A. Yeast/E. coli shuttle vectors with multiple unique restriction sites. Yeast. 2:1986;163-167.
33. Yaffe M.P., Schatz G. Two nuclear mutations that block mitochondrial protein import in yeast. Proc. Natl. Acad. Sci. USA. 81:1984;4819-4823.
34. Shoolingin-Jordan P.M. Porphobilinogen deaminase and uroporphyrinogen III synthase: structure, molecular biology, and mechanism. J. Bioenerg. Biomemb. 27:1995;181-196.
35. Alwan A.F., Mgbeje B.I.A., Jordan P.M. Purification and properties of uroporphyrinogen III synthase (co-synthase) from an overproducing recombinant strain of Escherichia coli K-12. Biochem. J. 264:1989;397-402.
36. Hart G.J., Battersby A.R. Purification and properties of uroporphyrinogen III synthase (co-synthetase) from Euglena gracilis. Biochem. J. 232:1985;151-160.
37. Tsai S.F., Bishop D.F., Desnick R.J. Purification and properties of uroporphyrinogen III synthase from human erythrocytes. J. Biol. Chem. 262:1987;1268-1273.