Enhancing stability and expression of recombinant human hemoglobin in E. coli: Progress in the development of a recombinant HBOC source

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 10, 2008, Pages 1471-1479

  Graves, Philip E ^a   Henderson, Douglas P ^b   Horstman, Molly J ^a   Solomon, Brian J ^a   Olson, John S ^a  

^a RICE UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS OF THE PERMIAN BASIN   (United States)

Author keywords

Globin expression; Globin folding; HBOC; Heme transport; Hemoglobin based oxygen carrier; Protein engineering

Indexed keywords

BLOOD SUBSTITUTE; GLOBIN; HEME; HEMOGLOBIN BASED OXYGEN CARRIER; HEMOGLOBIN DERIVATIVE; RECOMBINANT APOHEMOGLOBIN; RECOMBINANT HEMOGLOBIN; UNCLASSIFIED DRUG;

COST EFFECTIVENESS ANALYSIS; ESCHERICHIA COLI; HEMOGLOBIN SYNTHESIS; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN STABILITY; REVIEW;

BLOOD SUBSTITUTES; CLONING, MOLECULAR; COST-BENEFIT ANALYSIS; DRUG STABILITY; ESCHERICHIA COLI; GLOBINS; HEME; HEMOGLOBINS; HUMANS; PROTEIN ENGINEERING; PROTEIN FOLDING; RECOMBINANT PROTEINS;

BACTERIA (MICROORGANISMS); PHYSETERIDAE;

EID: 52049089667     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.04.012     Document Type: Review

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