Transplantation of insulin-secreting multicellular spheroids for the treatment of type 1 diabetes in mice

Journal of Controlled Release

Volumn 173, Issue 1, 2014, Pages 119-124

  Kusamori, Kosuke ^a   Nishikawa, Makiya ^a,b   Mizuno, Narumi ^a   Nishikawa, Tomoko ^a   Masuzawa, Akira ^a   Shimizu, Kazunori ^a,c   Konishi, Satoshi ^a,c   Takahashi, Yuki ^a,b   Takakura, Yoshinobu ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c RITSUMEIKAN UNIVERSITY   (Japan)

Author keywords

Allogeneic cell; Cell viability; Diabetes; Multicellular spheroid; Silicone elastomer; Transplantation

Indexed keywords

ALLOGENEIC CELLS; CELL VIABILITY; MOUSE INSULINOMA CELLS; MULTICELLULAR SPHEROID; POLY-N-ISOPROPYL ACRYLAMIDE; POLYDIMETHYLSILOXANE PDMS; SILICONE ELASTOMERS; SPHERICAL STRUCTURES;

ACRYLIC MONOMERS; CELL CULTURE; CELLS; COATINGS; INSULIN; MAMMALS; MEDICAL PROBLEMS; MICROCHANNELS; SILICONES; TRANSPLANTATION (SURGICAL);

MOLECULAR BIOLOGY;

DIMETICONE; GLUCOSE; INSULIN; POLY(N ISOPROPYLACRYLAMIDE); SILASTIC; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ADHESION; CELL SURVIVAL; CELL SUSPENSION; CELL THERAPY; CONTROLLED STUDY; DRUG RELEASE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; INSULINOMA; MALE; MOUSE; MULTICELLULAR SPHEROID; NONHUMAN; PRIORITY JOURNAL; STREPTOZOCIN DIABETES; THERAPY EFFECT;

ALLOGENEIC CELL; CELL VIABILITY; DIABETES; MULTICELLULAR SPHEROID; SILICONE ELASTOMER; TRANSPLANTATION;

ACRYLIC RESINS; ANIMALS; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIMETHYLPOLYSILOXANES; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; MICE, INBRED BALB C; SPHEROIDS, CELLULAR;

EID: 84887656524     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.10.024     Document Type: Article

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