The effect of multivalent Sonic hedgehog on differentiation of human embryonic stem cells into dopaminergic and GABAergic neurons

Biomaterials

Volumn 35, Issue 3, 2014, Pages 941-948

  Vazin, Tandis ^a   Ashton, Randolph S ^a   Conway, Anthony ^a   Rode, Nikhil A ^b   Lee, Susan M ^a   Bravo, Verenice ^a   Healy, Kevin E ^b   Kane, Ravi S ^c   Schaffer, David V ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Bioconjugates; Dopaminergic; GABAergic; Human pluripotent stem cells; Multivalency; Sonic hedgehog

Indexed keywords

BIOCONJUGATES; DOPAMINERGIC; GABAERGIC; MULTIVALENCY; PLURIPOTENT STEM CELLS; SONIC HEDGEHOGS;

AMINO ACIDS; BIOMOLECULES; LIGANDS; RECOMBINANT PROTEINS; STEM CELLS;

NEURONS;

4 AMINOBUTYRIC ACID RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR 8; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MICROTUBULE ASSOCIATED PROTEIN 2; NUCLEAR RECEPTOR RELATED FACTOR 1; OCTAMER TRANSCRIPTION FACTOR 4; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR MSX1; TRANSCRIPTION FACTOR OTX2; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR PITX3;

ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; EMBRYONIC STEM CELL; FOREBRAIN; HUMAN; HUMAN CELL; IN VITRO STUDY; MESENCEPHALON; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ERINACEIDAE;

BIOCONJUGATES; DOPAMINERGIC; GABAERGIC; HUMAN PLURIPOTENT STEM CELLS; MULTIVALENCY; SONIC HEDGEHOG;

ANIMALS; BIOCOMPATIBLE MATERIALS; CELL DIFFERENTIATION; CELL LINE; DOPAMINERGIC NEURONS; EMBRYONIC STEM CELLS; GABAERGIC NEURONS; HEDGEHOG PROTEINS; HUMANS; HYALURONIC ACID; PLURIPOTENT STEM CELLS;

EID: 84887625526     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.10.025     Document Type: Article

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