메뉴 건너뛰기




Volumn 340, Issue 2, 2013, Pages 270-276

Whole-exome sequencing reveals recurrent somatic mutation networks in cancer

Author keywords

Cancer; Somatic mutation network; Whole exome sequencing

Indexed keywords

DNA FRAGMENT; GENOMIC DNA;

EID: 84887616489     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.11.002     Document Type: Review
Times cited : (25)

References (67)
  • 1
    • 0036328380 scopus 로고    scopus 로고
    • Application of microarrays to the analysis of gene expression in cancer
    • Macgregor P.F., Squire J.A. Application of microarrays to the analysis of gene expression in cancer. Clin. Chem. 2002, 48:1170-1177.
    • (2002) Clin. Chem. , vol.48 , pp. 1170-1177
    • Macgregor, P.F.1    Squire, J.A.2
  • 2
    • 12444320350 scopus 로고    scopus 로고
    • Gene selection from microarray data for cancer classification - a machine learning approach
    • Wang Y., Tetko I.V., Hall M.A., Frank E., Facius A., et al. Gene selection from microarray data for cancer classification - a machine learning approach. Comput. Biol. Chem. 2005, 29:37-46.
    • (2005) Comput. Biol. Chem. , vol.29 , pp. 37-46
    • Wang, Y.1    Tetko, I.V.2    Hall, M.A.3    Frank, E.4    Facius, A.5
  • 3
    • 0141994858 scopus 로고    scopus 로고
    • Genomic microarrays in human genetic disease and cancer
    • Spec No. 2
    • Albertson D.G., Pinkel D. Genomic microarrays in human genetic disease and cancer. Hum. Mol. Genet. 2003, 12:R145-R152. Spec No. 2.
    • (2003) Hum. Mol. Genet. , vol.12
    • Albertson, D.G.1    Pinkel, D.2
  • 4
    • 74749083645 scopus 로고    scopus 로고
    • Discovery of prostate cancer biomarkers by microarray gene expression profiling
    • Sorensen K.D., Orntoft T.F. Discovery of prostate cancer biomarkers by microarray gene expression profiling. Expert Rev. Mol. Diagn. 2010, 10:49-64.
    • (2010) Expert Rev. Mol. Diagn. , vol.10 , pp. 49-64
    • Sorensen, K.D.1    Orntoft, T.F.2
  • 5
    • 79952356464 scopus 로고    scopus 로고
    • An integrated transcriptomic and computational analysis for biomarker identification in gastric cancer
    • Cui J., Chen Y., Chou W.C., Sun L., Chen L., et al. An integrated transcriptomic and computational analysis for biomarker identification in gastric cancer. Nucleic Acids Res. 2011, 39:1197-1207.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 1197-1207
    • Cui, J.1    Chen, Y.2    Chou, W.C.3    Sun, L.4    Chen, L.5
  • 6
    • 84863128658 scopus 로고    scopus 로고
    • Identifying disease genes and module biomarkers by differential interactions
    • Liu X., Liu Z.P., Zhao X.M., Chen L. Identifying disease genes and module biomarkers by differential interactions. J. Am. Med. Inform. Assoc. 2012, 19:241-248.
    • (2012) J. Am. Med. Inform. Assoc. , vol.19 , pp. 241-248
    • Liu, X.1    Liu, Z.P.2    Zhao, X.M.3    Chen, L.4
  • 7
    • 77956838065 scopus 로고    scopus 로고
    • Advances in understanding cancer genomes through second-generation sequencing
    • Meyerson M., Gabriel S., Getz G. Advances in understanding cancer genomes through second-generation sequencing. Nat. Rev. Genet. 2010, 11:685-696.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 685-696
    • Meyerson, M.1    Gabriel, S.2    Getz, G.3
  • 8
    • 7944238044 scopus 로고    scopus 로고
    • Somatic alterations in the human cancer genome
    • Weir B., Zhao X., Meyerson M. Somatic alterations in the human cancer genome. Cancer Cell 2004, 6:433-438.
    • (2004) Cancer Cell , vol.6 , pp. 433-438
    • Weir, B.1    Zhao, X.2    Meyerson, M.3
  • 9
    • 84861581164 scopus 로고    scopus 로고
    • Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
    • Barbieri C.E., Baca S.C., Lawrence M.S., Demichelis F., Blattner M., et al. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat. Genet. 2012, 44:685-689.
    • (2012) Nat. Genet. , vol.44 , pp. 685-689
    • Barbieri, C.E.1    Baca, S.C.2    Lawrence, M.S.3    Demichelis, F.4    Blattner, M.5
  • 10
    • 84555171449 scopus 로고    scopus 로고
    • Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
    • Quesada V., Conde L., Villamor N., Ordonez G.R., Jares P., et al. Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat. Genet. 2012, 44:47-52.
    • (2012) Nat. Genet. , vol.44 , pp. 47-52
    • Quesada, V.1    Conde, L.2    Villamor, N.3    Ordonez, G.R.4    Jares, P.5
  • 11
    • 79953176952 scopus 로고    scopus 로고
    • Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
    • Yan X.J., Xu J., Gu Z.H., Pan C.M., Lu G., et al. Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat. Genet. 2011, 43:309-315.
    • (2011) Nat. Genet. , vol.43 , pp. 309-315
    • Yan, X.J.1    Xu, J.2    Gu, Z.H.3    Pan, C.M.4    Lu, G.5
  • 12
    • 84860780495 scopus 로고    scopus 로고
    • De novo mutations revealed by whole-exome sequencing are strongly associated with autism
    • Sanders S.J., Murtha M.T., Gupta A.R., Murdoch J.D., Raubeson M.J., et al. De novo mutations revealed by whole-exome sequencing are strongly associated with autism. Nature 2012, 485:237-241.
    • (2012) Nature , vol.485 , pp. 237-241
    • Sanders, S.J.1    Murtha, M.T.2    Gupta, A.R.3    Murdoch, J.D.4    Raubeson, M.J.5
  • 13
    • 73349110071 scopus 로고    scopus 로고
    • Exome sequencing identifies the cause of a Mendelian disorder
    • Ng S.B., Buckingham K.J., Lee C., Bigham A.W., Tabor H.K., et al. Exome sequencing identifies the cause of a Mendelian disorder. Nat. Genet. 2010, 42:30-35.
    • (2010) Nat. Genet. , vol.42 , pp. 30-35
    • Ng, S.B.1    Buckingham, K.J.2    Lee, C.3    Bigham, A.W.4    Tabor, H.K.5
  • 14
    • 80052177544 scopus 로고    scopus 로고
    • Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
    • Agrawal N., Frederick M.J., Pickering C.R., Bettegowda C., Chang K., et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011, 333:1154-1157.
    • (2011) Science , vol.333 , pp. 1154-1157
    • Agrawal, N.1    Frederick, M.J.2    Pickering, C.R.3    Bettegowda, C.4    Chang, K.5
  • 16
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network Integrated genomic analyses of ovarian carcinoma. Nature 2011, 474:609-615.
    • (2011) Nature , vol.474 , pp. 609-615
  • 17
    • 70249111091 scopus 로고    scopus 로고
    • Targeted capture and massively parallel sequencing of 12 human exomes
    • Ng S.B., Turner E.H., Robertson P.D., Flygare S.D., Bigham A.W., et al. Targeted capture and massively parallel sequencing of 12 human exomes. Nature 2009, 461:272-276.
    • (2009) Nature , vol.461 , pp. 272-276
    • Ng, S.B.1    Turner, E.H.2    Robertson, P.D.3    Flygare, S.D.4    Bigham, A.W.5
  • 19
    • 58249138817 scopus 로고    scopus 로고
    • Generations of sequencing technologies
    • Pettersson E., Lundeberg J., Ahmadian A. Generations of sequencing technologies. Genomics 2009, 93:105-111.
    • (2009) Genomics , vol.93 , pp. 105-111
    • Pettersson, E.1    Lundeberg, J.2    Ahmadian, A.3
  • 20
    • 77949446630 scopus 로고    scopus 로고
    • Automated network analysis identifies core pathways in glioblastoma
    • Cerami E., Demir E., Schultz N., Taylor B.S., Sander C. Automated network analysis identifies core pathways in glioblastoma. PLoS ONE 2010, 5:e8918.
    • (2010) PLoS ONE , vol.5
    • Cerami, E.1    Demir, E.2    Schultz, N.3    Taylor, B.S.4    Sander, C.5
  • 21
    • 69749086899 scopus 로고    scopus 로고
    • Identification of rare cancer driver mutations by network reconstruction
    • Torkamani A., Schork N.J. Identification of rare cancer driver mutations by network reconstruction. Genome Res. 2009, 19:1570-1578.
    • (2009) Genome Res. , vol.19 , pp. 1570-1578
    • Torkamani, A.1    Schork, N.J.2
  • 22
    • 84856535081 scopus 로고    scopus 로고
    • Mutual exclusivity analysis identifies oncogenic network modules
    • Ciriello G., Cerami E., Sander C., Schultz N. Mutual exclusivity analysis identifies oncogenic network modules. Genome Res. 2012, 22:398-406.
    • (2012) Genome Res. , vol.22 , pp. 398-406
    • Ciriello, G.1    Cerami, E.2    Sander, C.3    Schultz, N.4
  • 23
    • 79953902594 scopus 로고    scopus 로고
    • Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors
    • Miller C.A., Settle S.H., Sulman E.P., Aldape K.D., Milosavljevic A. Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors. BMC Med. Genom. 2011, 4:34.
    • (2011) BMC Med. Genom. , vol.4 , pp. 34
    • Miller, C.A.1    Settle, S.H.2    Sulman, E.P.3    Aldape, K.D.4    Milosavljevic, A.5
  • 24
    • 79952198057 scopus 로고    scopus 로고
    • Exome sequencing: the sweet spot before whole genomes
    • Teer J.K., Mullikin J.C. Exome sequencing: the sweet spot before whole genomes. Hum. Mol. Genet. 2010, 19:R145-R151.
    • (2010) Hum. Mol. Genet. , vol.19
    • Teer, J.K.1    Mullikin, J.C.2
  • 25
    • 35748951614 scopus 로고    scopus 로고
    • Direct selection of human genomic loci by microarray hybridization
    • Albert T.J., Molla M.N., Muzny D.M., Nazareth L., Wheeler D., et al. Direct selection of human genomic loci by microarray hybridization. Nat. Methods 2007, 4:903-905.
    • (2007) Nat. Methods , vol.4 , pp. 903-905
    • Albert, T.J.1    Molla, M.N.2    Muzny, D.M.3    Nazareth, L.4    Wheeler, D.5
  • 26
  • 27
    • 36549021060 scopus 로고    scopus 로고
    • Genome-wide in situ exon capture for selective resequencing
    • Hodges E., Xuan Z., Balija V., Kramer M., Molla M.N., et al. Genome-wide in situ exon capture for selective resequencing. Nat. Genet. 2007, 39:1522-1527.
    • (2007) Nat. Genet. , vol.39 , pp. 1522-1527
    • Hodges, E.1    Xuan, Z.2    Balija, V.3    Kramer, M.4    Molla, M.N.5
  • 28
    • 66749159688 scopus 로고    scopus 로고
    • Hybrid selection of discrete genomic intervals on custom-designed microarrays for massively parallel sequencing
    • Hodges E., Rooks M., Xuan Z., Bhattacharjee A., Benjamin Gordon D. Hybrid selection of discrete genomic intervals on custom-designed microarrays for massively parallel sequencing. Nat. Protoc. 2009, 4:960-974.
    • (2009) Nat. Protoc. , vol.4 , pp. 960-974
    • Hodges, E.1    Rooks, M.2    Xuan, Z.3    Bhattacharjee, A.4    Benjamin Gordon, D.5
  • 29
    • 67649631522 scopus 로고    scopus 로고
    • Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection
    • Herman D.S., Hovingh G.K., Iartchouk O., Rehm H.L., Kucherlapati R., et al. Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection. Nat. Methods 2009, 6:507-510.
    • (2009) Nat. Methods , vol.6 , pp. 507-510
    • Herman, D.S.1    Hovingh, G.K.2    Iartchouk, O.3    Rehm, H.L.4    Kucherlapati, R.5
  • 30
    • 69749122811 scopus 로고    scopus 로고
    • Microarray-based multicycle-enrichment of genomic subsets for targeted next-generation sequencing
    • Summerer D., Wu H., Haase B., Cheng Y., Schracke N., et al. Microarray-based multicycle-enrichment of genomic subsets for targeted next-generation sequencing. Genome Res. 2009, 19:1616-1621.
    • (2009) Genome Res. , vol.19 , pp. 1616-1621
    • Summerer, D.1    Wu, H.2    Haase, B.3    Cheng, Y.4    Schracke, N.5
  • 31
  • 32
    • 59849113821 scopus 로고    scopus 로고
    • Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing
    • Gnirke A., Melnikov A., Maguire J., Rogov P., LeProust E.M., et al. Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing. Nat. Biotechnol. 2009, 27:182-189.
    • (2009) Nat. Biotechnol. , vol.27 , pp. 182-189
    • Gnirke, A.1    Melnikov, A.2    Maguire, J.3    Rogov, P.4    LeProust, E.M.5
  • 34
    • 68249105690 scopus 로고    scopus 로고
    • Multiplex padlock targeted sequencing reveals human hypermutable CpG variations
    • Li J.B., Gao Y., Aach J., Zhang K., Kryukov G.V., et al. Multiplex padlock targeted sequencing reveals human hypermutable CpG variations. Genome Res. 2009, 19:1606-1615.
    • (2009) Genome Res. , vol.19 , pp. 1606-1615
    • Li, J.B.1    Gao, Y.2    Aach, J.3    Zhang, K.4    Kryukov, G.V.5
  • 35
    • 35748953750 scopus 로고    scopus 로고
    • Multiplex amplification of large sets of human exons
    • Porreca G.J., Zhang K., Li J.B., Xie B., Austin D., et al. Multiplex amplification of large sets of human exons. Nat. Methods 2007, 4:931-936.
    • (2007) Nat. Methods , vol.4 , pp. 931-936
    • Porreca, G.J.1    Zhang, K.2    Li, J.B.3    Xie, B.4    Austin, D.5
  • 36
    • 67349179787 scopus 로고    scopus 로고
    • Massively parallel exon capture and library-free resequencing across 16 genomes
    • Turner E.H., Lee C., Ng S.B., Nickerson D.A., Shendure J. Massively parallel exon capture and library-free resequencing across 16 genomes. Nat. Methods 2009, 6:315-316.
    • (2009) Nat. Methods , vol.6 , pp. 315-316
    • Turner, E.H.1    Lee, C.2    Ng, S.B.3    Nickerson, D.A.4    Shendure, J.5
  • 37
    • 70349577993 scopus 로고    scopus 로고
    • Molecular inversion probe assay for allelic quantitation
    • Ji H., Welch K. Molecular inversion probe assay for allelic quantitation. Methods Mol. Biol. 2009, 556:67-87.
    • (2009) Methods Mol. Biol. , vol.556 , pp. 67-87
    • Ji, H.1    Welch, K.2
  • 38
    • 46449121669 scopus 로고    scopus 로고
    • Analysis of molecular inversion probe performance for allele copy number determination
    • Wang Y., Moorhead M., Karlin-Neumann G., Wang N.J., Ireland J., et al. Analysis of molecular inversion probe performance for allele copy number determination. Genome Biol. 2007, 8:R246.
    • (2007) Genome Biol. , vol.8
    • Wang, Y.1    Moorhead, M.2    Karlin-Neumann, G.3    Wang, N.J.4    Ireland, J.5
  • 39
    • 67650831473 scopus 로고    scopus 로고
    • Targeted retrieval and analysis of five Neandertal mtDNA genomes
    • Briggs A.W., Good J.M., Green R.E., Krause J., Maricic T., et al. Targeted retrieval and analysis of five Neandertal mtDNA genomes. Science 2009, 325:318-321.
    • (2009) Science , vol.325 , pp. 318-321
    • Briggs, A.W.1    Good, J.M.2    Green, R.E.3    Krause, J.4    Maricic, T.5
  • 40
    • 80055111869 scopus 로고    scopus 로고
    • Primer extension capture: targeted sequence retrieval from heavily degraded DNA sources
    • Briggs A.W., Good J.M., Green R.E., Krause J., Maricic T., et al. Primer extension capture: targeted sequence retrieval from heavily degraded DNA sources. J. Vis. Exp. 2009, 1573.
    • (2009) J. Vis. Exp. , pp. 1573
    • Briggs, A.W.1    Good, J.M.2    Green, R.E.3    Krause, J.4    Maricic, T.5
  • 42
    • 77956295988 scopus 로고    scopus 로고
    • The genome analysis toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data
    • McKenna A., Hanna M., Banks E., Sivachenko A., Cibulskis K., et al. The genome analysis toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. Genome Res. 2010, 20:1297-1303.
    • (2010) Genome Res. , vol.20 , pp. 1297-1303
    • McKenna, A.1    Hanna, M.2    Banks, E.3    Sivachenko, A.4    Cibulskis, K.5
  • 43
    • 69949122158 scopus 로고    scopus 로고
    • VarScan: variant detection in massively parallel sequencing of individual and pooled samples
    • Koboldt D.C., Chen K., Wylie T., Larson D.E., McLellan M.D., et al. VarScan: variant detection in massively parallel sequencing of individual and pooled samples. Bioinformatics 2009, 25:2283-2285.
    • (2009) Bioinformatics , vol.25 , pp. 2283-2285
    • Koboldt, D.C.1    Chen, K.2    Wylie, T.3    Larson, D.E.4    McLellan, M.D.5
  • 44
    • 74949101897 scopus 로고    scopus 로고
    • Inferring tumor progression from genomic heterogeneity
    • Navin N., Krasnitz A., Rodgers L., Cook K., Meth J., et al. Inferring tumor progression from genomic heterogeneity. Genome Res. 2010, 20:68-80.
    • (2010) Genome Res. , vol.20 , pp. 68-80
    • Navin, N.1    Krasnitz, A.2    Rodgers, L.3    Cook, K.4    Meth, J.5
  • 45
    • 84860782006 scopus 로고    scopus 로고
    • Absolute quantification of somatic DNA alterations in human cancer
    • Carter S.L., Cibulskis K., Helman E., McKenna A., Shen H., et al. Absolute quantification of somatic DNA alterations in human cancer. Nat. Biotechnol. 2012, 30:413-421.
    • (2012) Nat. Biotechnol. , vol.30 , pp. 413-421
    • Carter, S.L.1    Cibulskis, K.2    Helman, E.3    McKenna, A.4    Shen, H.5
  • 46
    • 55549097836 scopus 로고    scopus 로고
    • Mapping short DNA sequencing reads and calling variants using mapping quality scores
    • Li H., Ruan J., Durbin R. Mapping short DNA sequencing reads and calling variants using mapping quality scores. Genome Res. 2008, 18:1851-1858.
    • (2008) Genome Res. , vol.18 , pp. 1851-1858
    • Li, H.1    Ruan, J.2    Durbin, R.3
  • 47
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B., Trapnell C., Pop M., Salzberg S.L. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 2009, 10:R25.
    • (2009) Genome Biol. , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 48
    • 77951957381 scopus 로고    scopus 로고
    • SNVMix: predicting single nucleotide variants from next-generation sequencing of tumors
    • Goya R., Sun M.G., Morin R.D., Leung G., Ha G., et al. SNVMix: predicting single nucleotide variants from next-generation sequencing of tumors. Bioinformatics 2010, 26:730-736.
    • (2010) Bioinformatics , vol.26 , pp. 730-736
    • Goya, R.1    Sun, M.G.2    Morin, R.D.3    Leung, G.4    Ha, G.5
  • 49
    • 84859249611 scopus 로고    scopus 로고
    • JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data
    • Roth A., Ding J., Morin R., Crisan A., Ha G., et al. JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data. Bioinformatics 2012, 28:907-913.
    • (2012) Bioinformatics , vol.28 , pp. 907-913
    • Roth, A.1    Ding, J.2    Morin, R.3    Crisan, A.4    Ha, G.5
  • 50
    • 84856565531 scopus 로고    scopus 로고
    • SomaticSniper: identification of somatic point mutations in whole genome sequencing data
    • Larson D.E., Harris C.C., Chen K., Koboldt D.C., Abbott T.E., et al. SomaticSniper: identification of somatic point mutations in whole genome sequencing data. Bioinformatics 2012, 28:311-317.
    • (2012) Bioinformatics , vol.28 , pp. 311-317
    • Larson, D.E.1    Harris, C.C.2    Chen, K.3    Koboldt, D.C.4    Abbott, T.E.5
  • 51
    • 84863229597 scopus 로고    scopus 로고
    • VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing
    • Koboldt D.C., Zhang Q., Larson D.E., Shen D., McLellan M.D., et al. VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res. 2012, 22:568-576.
    • (2012) Genome Res. , vol.22 , pp. 568-576
    • Koboldt, D.C.1    Zhang, Q.2    Larson, D.E.3    Shen, D.4    McLellan, M.D.5
  • 52
    • 55549101623 scopus 로고    scopus 로고
    • DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
    • Ley T.J., Mardis E.R., Ding L., Fulton B., McLellan M.D., et al. DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 2008, 456:66-72.
    • (2008) Nature , vol.456 , pp. 66-72
    • Ley, T.J.1    Mardis, E.R.2    Ding, L.3    Fulton, B.4    McLellan, M.D.5
  • 53
    • 70149093912 scopus 로고    scopus 로고
    • Recurring mutations found by sequencing an acute myeloid leukemia genome
    • Mardis E.R., Ding L., Dooling D.J., Larson D.E., McLellan M.D., et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N. Engl. J. Med. 2009, 361:1058-1066.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 1058-1066
    • Mardis, E.R.1    Ding, L.2    Dooling, D.J.3    Larson, D.E.4    McLellan, M.D.5
  • 54
    • 0021242388 scopus 로고
    • Tumor heterogeneity
    • Heppner G.H. Tumor heterogeneity. Cancer Res. 1984, 44:2259-2265.
    • (1984) Cancer Res. , vol.44 , pp. 2259-2265
    • Heppner, G.H.1
  • 56
    • 34547566118 scopus 로고    scopus 로고
    • CanPredict: a computational tool for predicting cancer-associated missense mutations
    • Kaminker J.S., Zhang Y., Watanabe C., Zhang Z. CanPredict: a computational tool for predicting cancer-associated missense mutations. Nucleic Acids Res. 2007, 35:W595-W598.
    • (2007) Nucleic Acids Res. , vol.35
    • Kaminker, J.S.1    Zhang, Y.2    Watanabe, C.3    Zhang, Z.4
  • 57
    • 69249115697 scopus 로고    scopus 로고
    • Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations
    • Carter H., Chen S., Isik L., Tyekucheva S., Velculescu V.E., et al. Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations. Cancer Res. 2009, 69:6660-6667.
    • (2009) Cancer Res. , vol.69 , pp. 6660-6667
    • Carter, H.1    Chen, S.2    Isik, L.3    Tyekucheva, S.4    Velculescu, V.E.5
  • 58
    • 46949084265 scopus 로고    scopus 로고
    • Defining the blueprint of the cancer genome
    • Velculescu V.E. Defining the blueprint of the cancer genome. Carcinogenesis 2008, 29:1087-1091.
    • (2008) Carcinogenesis , vol.29 , pp. 1087-1091
    • Velculescu, V.E.1
  • 61
    • 52949127312 scopus 로고    scopus 로고
    • An integrated genomic analysis of human glioblastoma multiforme
    • Parsons D.W., Jones S., Zhang X., Lin J.C., Leary R.J., et al. An integrated genomic analysis of human glioblastoma multiforme. Science 2008, 321:1807-1812.
    • (2008) Science , vol.321 , pp. 1807-1812
    • Parsons, D.W.1    Jones, S.2    Zhang, X.3    Lin, J.C.4    Leary, R.J.5
  • 62
    • 34548388340 scopus 로고    scopus 로고
    • A multidimensional analysis of genes mutated in breast and colorectal cancers
    • Lin J., Gan C.M., Zhang X., Jones S., Sjoblom T., et al. A multidimensional analysis of genes mutated in breast and colorectal cancers. Genome Res. 2007, 17:1304-1318.
    • (2007) Genome Res. , vol.17 , pp. 1304-1318
    • Lin, J.1    Gan, C.M.2    Zhang, X.3    Jones, S.4    Sjoblom, T.5
  • 63
    • 84856532705 scopus 로고    scopus 로고
    • De novo discovery of mutated driver pathways in cancer
    • Vandin F., Upfal E., Raphael B.J. De novo discovery of mutated driver pathways in cancer. Genome Res. 2012, 22:375-385.
    • (2012) Genome Res. , vol.22 , pp. 375-385
    • Vandin, F.1    Upfal, E.2    Raphael, B.J.3
  • 64
    • 84861893428 scopus 로고    scopus 로고
    • Coexpression network analysis in chronic hepatitis B and C hepatic lesion reveals distinct patterns of disease progression to hepatocellular carcinoma
    • He D., Liu Z., Honda M., Kaneko S., Chen L. Coexpression network analysis in chronic hepatitis B and C hepatic lesion reveals distinct patterns of disease progression to hepatocellular carcinoma. J. Mol. Cell Biol. 2012, 4(3):140-152.
    • (2012) J. Mol. Cell Biol. , vol.4 , Issue.3 , pp. 140-152
    • He, D.1    Liu, Z.2    Honda, M.3    Kaneko, S.4    Chen, L.5
  • 65
    • 84883000768 scopus 로고    scopus 로고
    • An integrated approach to identify causal network modules of complex diseases with application to colorectal cancer
    • Wen Z., Liu Z., Liu Z., Zhang Y., Chen L. An integrated approach to identify causal network modules of complex diseases with application to colorectal cancer. J. Am. Med. Inform. Assoc. 2012, 10.1136/amiajnl-2012-001168.
    • (2012) J. Am. Med. Inform. Assoc.
    • Wen, Z.1    Liu, Z.2    Liu, Z.3    Zhang, Y.4    Chen, L.5
  • 66
    • 84859741480 scopus 로고    scopus 로고
    • Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers
    • Chen L., Liu R., Liu Z., Li M., Aihara K. Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers. Sci. Rep. 2012, 2:342. 10.1038/srep0034.
    • (2012) Sci. Rep. , vol.2 , pp. 342
    • Chen, L.1    Liu, R.2    Liu, Z.3    Li, M.4    Aihara, K.5
  • 67
    • 84871750865 scopus 로고    scopus 로고
    • Identifying critical transitions and their leading networks in complex diseases
    • Liu R., Li M., Liu Z., Wu J., Chen L., Aihara K. Identifying critical transitions and their leading networks in complex diseases. Sci. Rep. 2012, 2:813. 10.1038/srep00813.
    • (2012) Sci. Rep. , vol.2 , pp. 813
    • Liu, R.1    Li, M.2    Liu, Z.3    Wu, J.4    Chen, L.5    Aihara, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.