메뉴 건너뛰기




Volumn 130, Issue 11-12, 2013, Pages 532-552

Gbx2 functions as a transcriptional repressor to regulate the specification and morphogenesis of the mid-hindbrain junction in a dosage- and stage-dependent manner

Author keywords

Brain formation; Domain structure; Gbx2; Midbrain hindbrain boundary; Transcriptional regulation; Zebrafish

Indexed keywords

GBX TRNASCRIPTION FACTOR; HOMEODOMAIN PROTEIN; MESSENGER RNA; PROLINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 84887608344     PISSN: 09254773     EISSN: 18726356     Source Type: Journal    
DOI: 10.1016/j.mod.2013.07.004     Document Type: Article
Times cited : (20)

References (62)
  • 2
    • 0033539094 scopus 로고    scopus 로고
    • The caudal limit of Otx2 expression positions the isthmic organizer
    • Broccoli V., Boncinelli E., Wurst W. The caudal limit of Otx2 expression positions the isthmic organizer. Nature 1999, 401:164-168.
    • (1999) Nature , vol.401 , pp. 164-168
    • Broccoli, V.1    Boncinelli, E.2    Wurst, W.3
  • 4
    • 0027232546 scopus 로고
    • Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries
    • Bulfone A., Puelles L., Porteus M.H., Frohman M.A., Martin G.R., Rubenstein J.L.R. Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J. Neurosci. 1993, 13:3155-3172.
    • (1993) J. Neurosci. , vol.13 , pp. 3155-3172
    • Bulfone, A.1    Puelles, L.2    Porteus, M.H.3    Frohman, M.A.4    Martin, G.R.5    Rubenstein, J.L.R.6
  • 5
    • 79952636213 scopus 로고    scopus 로고
    • Evolutionarily conserved function of Gbx2 in anterior hindbrain development
    • Burroughs-Garcia J., Sittaramane V., Chandrasekhar A., Waters S.T. Evolutionarily conserved function of Gbx2 in anterior hindbrain development. Dev. Dyn. 2011, 240:828-838.
    • (2011) Dev. Dyn. , vol.240 , pp. 828-838
    • Burroughs-Garcia, J.1    Sittaramane, V.2    Chandrasekhar, A.3    Waters, S.T.4
  • 6
    • 67650760557 scopus 로고    scopus 로고
    • Transcription factor Gbx2 acts cell-nonautonomously to regulate the formation of lineage-restriction boundaries of the thalamus
    • Chen L., Guo Q., Li J.Y.H. Transcription factor Gbx2 acts cell-nonautonomously to regulate the formation of lineage-restriction boundaries of the thalamus. Development 2009, 136:1317-1326.
    • (2009) Development , vol.136 , pp. 1317-1326
    • Chen, L.1    Guo, Q.2    Li, J.Y.H.3
  • 7
    • 0029960330 scopus 로고    scopus 로고
    • Midbrain development induced by FGF8 in the chick embryo
    • Crossley P.H., Martinez S., Martin G.R. Midbrain development induced by FGF8 in the chick embryo. Nature 1996, 380:66-68.
    • (1996) Nature , vol.380 , pp. 66-68
    • Crossley, P.H.1    Martinez, S.2    Martin, G.R.3
  • 9
    • 0024386412 scopus 로고
    • A chicken homeo box gene with developmentally regulated expression
    • Fainsod A., Greunbaum Y. A chicken homeo box gene with developmentally regulated expression. FEBS Lett. 1989, 250:381-385.
    • (1989) FEBS Lett. , vol.250 , pp. 381-385
    • Fainsod, A.1    Greunbaum, Y.2
  • 10
    • 0034931142 scopus 로고    scopus 로고
    • Sprouty4 acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish
    • Fürthauer M., Reifers F., Brand M., Thisse B., Thisse C. Sprouty4 acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish. Development 2001, 128:2175-2186.
    • (2001) Development , vol.128 , pp. 2175-2186
    • Fürthauer, M.1    Reifers, F.2    Brand, M.3    Thisse, B.4    Thisse, C.5
  • 12
    • 0035114788 scopus 로고    scopus 로고
    • Neuroepithelial co-expression of Gbx2 and Otx2 precedes Fgf8 expression in the isthmic organizer
    • Garda A.-L., Echevarria D., Martinez S. Neuroepithelial co-expression of Gbx2 and Otx2 precedes Fgf8 expression in the isthmic organizer. Mech. Dev. 2001, 101:111-118.
    • (2001) Mech. Dev. , vol.101 , pp. 111-118
    • Garda, A.-L.1    Echevarria, D.2    Martinez, S.3
  • 13
    • 0036023310 scopus 로고    scopus 로고
    • The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation
    • Glavic A., Gomez-Skarmeta J.L., Mayor R. The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation. Development 2002, 129:1609-1621.
    • (2002) Development , vol.129 , pp. 1609-1621
    • Glavic, A.1    Gomez-Skarmeta, J.L.2    Mayor, R.3
  • 14
    • 55249119488 scopus 로고    scopus 로고
    • Formation of the zebrafish midbrain-hindbrain boundary constriction requires laminin-dependent basal constriction
    • Gutzman J.H., Graeden E.G., Lowery L.A., Holley H.S., Sive H. Formation of the zebrafish midbrain-hindbrain boundary constriction requires laminin-dependent basal constriction. Mech. Dev. 2008, 125:974-983.
    • (2008) Mech. Dev. , vol.125 , pp. 974-983
    • Gutzman, J.H.1    Graeden, E.G.2    Lowery, L.A.3    Holley, H.S.4    Sive, H.5
  • 17
    • 0038820118 scopus 로고    scopus 로고
    • An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila
    • Hirth F., Kammermeier L., Frei E., Walldorf U., Noll M., Reichert H. An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila. Development 2003, 130:2365-2373.
    • (2003) Development , vol.130 , pp. 2365-2373
    • Hirth, F.1    Kammermeier, L.2    Frei, E.3    Walldorf, U.4    Noll, M.5    Reichert, H.6
  • 19
    • 41149150649 scopus 로고    scopus 로고
    • Transcription of fgf8 is regulated by activating and repressive cis-elements at the midbrain-hindbrain boundary in zebrafish embryos
    • Inoue F., Parvin M.S., Yamasu K. Transcription of fgf8 is regulated by activating and repressive cis-elements at the midbrain-hindbrain boundary in zebrafish embryos. Dev. Biol. 2008, 316:471-486.
    • (2008) Dev. Biol. , vol.316 , pp. 471-486
    • Inoue, F.1    Parvin, M.S.2    Yamasu, K.3
  • 20
    • 84864024007 scopus 로고    scopus 로고
    • Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors
    • Inoue F., Kurokawa D., Takahashi M., Aizawa S. Gbx2 directly restricts Otx2 expression to forebrain and midbrain, competing with class III POU factors. Mol. Cell. Biol. 2012, 32:2618-2627.
    • (2012) Mol. Cell. Biol. , vol.32 , pp. 2618-2627
    • Inoue, F.1    Kurokawa, D.2    Takahashi, M.3    Aizawa, S.4
  • 21
    • 33751505034 scopus 로고    scopus 로고
    • Three enhancer regions regulate gbx2 gene expression in the isthmic region during zebrafish development
    • Islam M.E., Kikuta H., Inoue F., Kanai M., Kawakami A., Parvin M.S., Takeda H., Yamasu K. Three enhancer regions regulate gbx2 gene expression in the isthmic region during zebrafish development. Mech. Dev. 2006, 123:907-924.
    • (2006) Mech. Dev. , vol.123 , pp. 907-924
    • Islam, M.E.1    Kikuta, H.2    Inoue, F.3    Kanai, M.4    Kawakami, A.5    Parvin, M.S.6    Takeda, H.7    Yamasu, K.8
  • 22
    • 0345471389 scopus 로고    scopus 로고
    • A conserved motif in goosecoid mediates groucho-dependent repression in Drosophila embryos
    • Jiménez G., Verrijzer C.P., Ish-Horowicz D. A conserved motif in goosecoid mediates groucho-dependent repression in Drosophila embryos. Mol. Cell. Biol. 1999, 19:2080-2087.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2080-2087
    • Jiménez, G.1    Verrijzer, C.P.2    Ish-Horowicz, D.3
  • 23
    • 0020326857 scopus 로고
    • Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells
    • Jones-Villeneuve E.M.V., McBurney M.W., Rogers K.A., Kalnins V.I. Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J. Cell Biol. 1982, 94:253-262.
    • (1982) J. Cell Biol. , vol.94 , pp. 253-262
    • Jones-Villeneuve, E.M.V.1    McBurney, M.W.2    Rogers, K.A.3    Kalnins, V.I.4
  • 25
    • 38449110499 scopus 로고    scopus 로고
    • Tol2: a versatile gene transfer vector in vertebrates
    • Kawakami K. Tol2: a versatile gene transfer vector in vertebrates. Genome Biol. 2007, 8(Suppl. 1):S7.
    • (2007) Genome Biol. , vol.8 , Issue.SUPPL. 1
    • Kawakami, K.1
  • 26
    • 43249111060 scopus 로고    scopus 로고
    • Activator-to-repressor conversion of T-box transcription factors by the Ripply family of Groucho/TLE-associated mediators
    • Kawamura A., Koshida S., Takada S. Activator-to-repressor conversion of T-box transcription factors by the Ripply family of Groucho/TLE-associated mediators. Mol. Cell. Biol. 2008, 28:3236-3244.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 3236-3244
    • Kawamura, A.1    Koshida, S.2    Takada, S.3
  • 27
    • 0033950079 scopus 로고    scopus 로고
    • The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains
    • Kay B.K., Williamson M.P., Sudol M. The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains. FASEB J. 2000, 14:231-241.
    • (2000) FASEB J. , vol.14 , pp. 231-241
    • Kay, B.K.1    Williamson, M.P.2    Sudol, M.3
  • 28
    • 84867895543 scopus 로고    scopus 로고
    • Pou2, a class V POU-type transcription factor in zebrafish, regulates dorsoventral patterning and convergent extension movement at different blastula stages
    • Khan A., Nakamoto A., Okamoto S., Tai M., Nakayama Y., Kobayashi K., Kawamura A., Takeda H., Yamasu K. Pou2, a class V POU-type transcription factor in zebrafish, regulates dorsoventral patterning and convergent extension movement at different blastula stages. Mech. Dev. 2012, 129:219-235.
    • (2012) Mech. Dev. , vol.129 , pp. 219-235
    • Khan, A.1    Nakamoto, A.2    Okamoto, S.3    Tai, M.4    Nakayama, Y.5    Kobayashi, K.6    Kawamura, A.7    Takeda, H.8    Yamasu, K.9
  • 29
    • 84866624996 scopus 로고    scopus 로고
    • Mesendoderm specification depends on the function of Pou2, the class V POU-type transcription factor, during zebrafish embryogenesis
    • Khan A., Nakamoto A., Tai M., Saito S., Nakayama Y., Kawamura A., Takeda H., Yamasu K. Mesendoderm specification depends on the function of Pou2, the class V POU-type transcription factor, during zebrafish embryogenesis. Develop. Growth Differ. 2012, 54:686-701.
    • (2012) Develop. Growth Differ. , vol.54 , pp. 686-701
    • Khan, A.1    Nakamoto, A.2    Tai, M.3    Saito, S.4    Nakayama, Y.5    Kawamura, A.6    Takeda, H.7    Yamasu, K.8
  • 30
    • 0242558206 scopus 로고    scopus 로고
    • Gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain
    • Kikuta H., Kanai M., Ito Y., Yamasu K. Gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain. Dev. Dyn. 2003, 228:433-450.
    • (2003) Dev. Dyn. , vol.228 , pp. 433-450
    • Kikuta, H.1    Kanai, M.2    Ito, Y.3    Yamasu, K.4
  • 32
    • 0031904233 scopus 로고    scopus 로고
    • Anterior structural defects by misexpression of Xgbx-2 in early Xenopus embryos are associated with altered expression of cell adhesion molecules
    • King M.W., Ndiema M., Neff A.W. Anterior structural defects by misexpression of Xgbx-2 in early Xenopus embryos are associated with altered expression of cell adhesion molecules. Dev. Dyn. 1998, 212:563-579.
    • (1998) Dev. Dyn. , vol.212 , pp. 563-579
    • King, M.W.1    Ndiema, M.2    Neff, A.W.3
  • 33
    • 0030689039 scopus 로고    scopus 로고
    • The homeobox gene GBX2, a target of the myb oncogene, mediates autocrine growth and monocyte differentiation
    • Kowenz-Leutz E., Herr P., Niss K., Leutz A. The homeobox gene GBX2, a target of the myb oncogene, mediates autocrine growth and monocyte differentiation. Cell 1997, 91:185-195.
    • (1997) Cell , vol.91 , pp. 185-195
    • Kowenz-Leutz, E.1    Herr, P.2    Niss, K.3    Leutz, A.4
  • 34
    • 70349897766 scopus 로고    scopus 로고
    • The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction
    • Li B., Kuriyama S., Moreno M., Mayor R. The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction. Development 2009, 136:3267-3278.
    • (2009) Development , vol.136 , pp. 3267-3278
    • Li, B.1    Kuriyama, S.2    Moreno, M.3    Mayor, R.4
  • 35
    • 0037179758 scopus 로고    scopus 로고
    • Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer
    • Li J.Y.H., Lao Z., Joyner A.L. Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer. Neuron 2002, 36:31-43.
    • (2002) Neuron , vol.36 , pp. 31-43
    • Li, J.Y.H.1    Lao, Z.2    Joyner, A.L.3
  • 36
    • 18844453956 scopus 로고    scopus 로고
    • New regulatory interactions and cellular responses in the isthmic organizer region revealed by altering Gbx2 expression
    • Li J.Y.H., Lao Z., Joyner A.L. New regulatory interactions and cellular responses in the isthmic organizer region revealed by altering Gbx2 expression. Development 2005, 132:1971-1981.
    • (2005) Development , vol.132 , pp. 1971-1981
    • Li, J.Y.H.1    Lao, Z.2    Joyner, A.L.3
  • 37
    • 0027054925 scopus 로고
    • Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions
    • Logan C., Hanks M.C., Noble-Topham S., Nallainathan D., Provart N.J., Joyner A.L. Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions. Dev. Genet. 1992, 13:345-358.
    • (1992) Dev. Genet. , vol.13 , pp. 345-358
    • Logan, C.1    Hanks, M.C.2    Noble-Topham, S.3    Nallainathan, D.4    Provart, N.J.5    Joyner, A.L.6
  • 38
    • 19744375206 scopus 로고    scopus 로고
    • Initial formation of zebrafish brain ventricles occurs independently of circulation and requires the nagie oko and snakehead/atp1a1a.1 gene products
    • Lowery L.A., Sive H. Initial formation of zebrafish brain ventricles occurs independently of circulation and requires the nagie oko and snakehead/atp1a1a.1 gene products. Development 2005, 132:2057-2067.
    • (2005) Development , vol.132 , pp. 2057-2067
    • Lowery, L.A.1    Sive, H.2
  • 39
    • 0032908043 scopus 로고    scopus 로고
    • FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression
    • Martinez S., Crossley P.H., Cobos I., Rubenstein J.L.R., Martin G.R. FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression. Development 1999, 126:1189-1200.
    • (1999) Development , vol.126 , pp. 1189-1200
    • Martinez, S.1    Crossley, P.H.2    Cobos, I.3    Rubenstein, J.L.R.4    Martin, G.R.5
  • 40
    • 0027370920 scopus 로고
    • The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosomes 2 and 7 in humans
    • Matsui T., Hirai M., Hirano M., Kurosawa Y. The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosomes 2 and 7 in humans. FEBS Lett. 1993, 336:107-110.
    • (1993) FEBS Lett. , vol.336 , pp. 107-110
    • Matsui, T.1    Hirai, M.2    Hirano, M.3    Kurosawa, Y.4
  • 41
    • 0024340524 scopus 로고
    • The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain
    • Mermod N., O'Neill E.A., Kelly T.J., Tjian R. The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain. Cell 1989, 58:741-753.
    • (1989) Cell , vol.58 , pp. 741-753
    • Mermod, N.1    O'Neill, E.A.2    Kelly, T.J.3    Tjian, R.4
  • 42
    • 0033539146 scopus 로고    scopus 로고
    • A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer
    • Millet S., Campbell K., Epstein D.J., Losos K., Harris E., Joyner A.L. A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer. Nature 1999, 401:161-164.
    • (1999) Nature , vol.401 , pp. 161-164
    • Millet, S.1    Campbell, K.2    Epstein, D.J.3    Losos, K.4    Harris, E.5    Joyner, A.L.6
  • 43
    • 0345034824 scopus 로고    scopus 로고
    • Expression of the Ets transcription factors erm and pea3 in early zebrafish development
    • Münchberg S.R., Ober E.A., Steinbeisser H. Expression of the Ets transcription factors erm and pea3 in early zebrafish development. Mech. Dev. 1999, 88:233-236.
    • (1999) Mech. Dev. , vol.88 , pp. 233-236
    • Münchberg, S.R.1    Ober, E.A.2    Steinbeisser, H.3
  • 45
    • 0035060985 scopus 로고    scopus 로고
    • Regionalization of the optic tectum: combinations of gene expression that define the tectum
    • Nakamura H. Regionalization of the optic tectum: combinations of gene expression that define the tectum. Trends Neurosci. 2001, 24:32-39.
    • (2001) Trends Neurosci. , vol.24 , pp. 32-39
    • Nakamura, H.1
  • 46
    • 0031926506 scopus 로고    scopus 로고
    • Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis
    • Reifers F., Bohli H., Walsh E.C., Crossley P.H., Stainier D.Y.R., Brand M. Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 1998, 125:2381-2395.
    • (1998) Development , vol.125 , pp. 2381-2395
    • Reifers, F.1    Bohli, H.2    Walsh, E.C.3    Crossley, P.H.4    Stainier, D.Y.R.5    Brand, M.6
  • 47
    • 0035252737 scopus 로고    scopus 로고
    • The midbrain-hindbrain boundary organizer
    • Rhinn M., Brand M. The midbrain-hindbrain boundary organizer. Curr. Opin. Neurobiol. 2001, 11:34-42.
    • (2001) Curr. Opin. Neurobiol. , vol.11 , pp. 34-42
    • Rhinn, M.1    Brand, M.2
  • 48
    • 65449171950 scopus 로고    scopus 로고
    • Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal
    • Rhinn M., Lun K., Ahrendt R., Geffarth M., Brand M. Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal. Neural Dev. 2009, 4:12.
    • (2009) Neural Dev. , vol.4 , pp. 12
    • Rhinn, M.1    Lun, K.2    Ahrendt, R.3    Geffarth, M.4    Brand, M.5
  • 49
    • 0042831172 scopus 로고    scopus 로고
    • Cloning, expression and relationship of zebrafish gbx1 and gbx2 genes to Fgf signaling
    • Rhinn M., Lun K., Amores A., Yan Y.-L., Postlethwait J.H., Brand M. Cloning, expression and relationship of zebrafish gbx1 and gbx2 genes to Fgf signaling. Mech. Dev. 2003, 120:919-936.
    • (2003) Mech. Dev. , vol.120 , pp. 919-936
    • Rhinn, M.1    Lun, K.2    Amores, A.3    Yan, Y.-L.4    Postlethwait, J.H.5    Brand, M.6
  • 50
    • 0942287277 scopus 로고    scopus 로고
    • Isolation and expression of the homeobox gene Gbx1 during mouse development
    • Rhinn M., Lun K., Werner M., Simeone A., Brand M. Isolation and expression of the homeobox gene Gbx1 during mouse development. Dev. Dyn. 2004, 229:334-339.
    • (2004) Dev. Dyn. , vol.229 , pp. 334-339
    • Rhinn, M.1    Lun, K.2    Werner, M.3    Simeone, A.4    Brand, M.5
  • 52
    • 0034214298 scopus 로고    scopus 로고
    • Positioning the isthmic organizer where Otx2 and Gbx2 meet
    • Simeone A. Positioning the isthmic organizer where Otx2 and Gbx2 meet. Trends Genet. 2000, 16:237-240.
    • (2000) Trends Genet. , vol.16 , pp. 237-240
    • Simeone, A.1
  • 53
    • 84861699723 scopus 로고    scopus 로고
    • Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning
    • Steventon B., Mayor R., Streit A. Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning. Dev. Biol. 2012, 367:55-65.
    • (2012) Dev. Biol. , vol.367 , pp. 55-65
    • Steventon, B.1    Mayor, R.2    Streit, A.3
  • 54
    • 73249139732 scopus 로고    scopus 로고
    • Misexpression of Gbx2 throughout the mesencephalon by a conditional gain-of-function transgene leads to deletion of the midbrain and cerebellum in mice
    • Sunmonu N.A., Chen L., Li J.Y.H. Misexpression of Gbx2 throughout the mesencephalon by a conditional gain-of-function transgene leads to deletion of the midbrain and cerebellum in mice. Genesis 2009, 47:667-673.
    • (2009) Genesis , vol.47 , pp. 667-673
    • Sunmonu, N.A.1    Chen, L.2    Li, J.Y.H.3
  • 55
    • 79951522779 scopus 로고    scopus 로고
    • Gbx2 and Fgf8 are sequentially required for formation of the midbrain-hindbrain compartment boundary
    • Sunmonu N.A., Li K., Guo Q., Li J.Y.H. Gbx2 and Fgf8 are sequentially required for formation of the midbrain-hindbrain compartment boundary. Development 2011, 138:725-734.
    • (2011) Development , vol.138 , pp. 725-734
    • Sunmonu, N.A.1    Li, K.2    Guo, Q.3    Li, J.Y.H.4
  • 56
    • 0031895523 scopus 로고    scopus 로고
    • Two distinct types of repression domain in engrailed: one interacts with the groucho corepressor and is preferentially active on integrated target genes
    • Tolkunova E.N., Fujioka M., Kobayashi M., Deka D., Jaynes J.B. Two distinct types of repression domain in engrailed: one interacts with the groucho corepressor and is preferentially active on integrated target genes. Mol. Cell. Biol. 1998, 18:2804-2814.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2804-2814
    • Tolkunova, E.N.1    Fujioka, M.2    Kobayashi, M.3    Deka, D.4    Jaynes, J.B.5
  • 57
    • 0036179092 scopus 로고    scopus 로고
    • Gbx2 interacts with Otx2 and patterns the anterior-posterior axis during gastrulation in Xenopus
    • Tour E., Pillemer G., Gruenbaum Y., Fainsod A. Gbx2 interacts with Otx2 and patterns the anterior-posterior axis during gastrulation in Xenopus. Mech. Dev. 2002, 112:141-151.
    • (2002) Mech. Dev. , vol.112 , pp. 141-151
    • Tour, E.1    Pillemer, G.2    Gruenbaum, Y.3    Fainsod, A.4
  • 58
    • 0035660118 scopus 로고    scopus 로고
    • Otx2 can activate the isthmic organizer genetic network in the Xenopus embryo
    • Tour E., Pillemer G., Gruenbaum Y., Fainsod A. Otx2 can activate the isthmic organizer genetic network in the Xenopus embryo. Mech. Dev. 2002, 110:3-13.
    • (2002) Mech. Dev. , vol.110 , pp. 3-13
    • Tour, E.1    Pillemer, G.2    Gruenbaum, Y.3    Fainsod, A.4
  • 59
    • 33750433896 scopus 로고    scopus 로고
    • Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition
    • Urasaki A., Morvan G., Kawakami K. Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition. Genetics 2006, 174:639-649.
    • (2006) Genetics , vol.174 , pp. 639-649
    • Urasaki, A.1    Morvan, G.2    Kawakami, K.3
  • 60
    • 0030851192 scopus 로고    scopus 로고
    • Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function
    • Wassarman K.M., Lewandoski M., Campbell K., Joyner A.L., Rubenstein J.L.R., Martinez S., Martin G.R. Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development 1997, 124:2923-2934.
    • (1997) Development , vol.124 , pp. 2923-2934
    • Wassarman, K.M.1    Lewandoski, M.2    Campbell, K.3    Joyner, A.L.4    Rubenstein, J.L.R.5    Martinez, S.6    Martin, G.R.7
  • 61
    • 33745071492 scopus 로고    scopus 로고
    • A threshold requirement for Gbx2 levels in hindbrain development
    • Waters S.T., Lewandoski M. A threshold requirement for Gbx2 levels in hindbrain development. Development 2006, 133:1991-2000.
    • (2006) Development , vol.133 , pp. 1991-2000
    • Waters, S.T.1    Lewandoski, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.