Misexpression of Gbx2 throughout the mesencephalon by a conditional gain-of-function transgene leads to deletion of the midbrain and cerebellum in mice

Genesis

Volumn 47, Issue 10, 2009, Pages 667-673

  Sunmonu, N Abimbola ^a   Chen, Li ^a   Li, James Y H ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Conditional gain of function; Cre; Fgf8; Gbx2; Transcription factor

Indexed keywords

BETA GALACTOSIDASE; CRE RECOMBINASE; FIBROBLAST GROWTH FACTOR 8; HOMEODOMAIN PROTEIN; PROTEIN GBX2; TRANSCRIPTION FACTOR OTX2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CEREBELLUM; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; FOREBRAIN; GENE ACTIVATION; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION; GENE FREQUENCY; GENE FUNCTION; GENETIC RECOMBINATION; GENETIC VARIABILITY; MESENCEPHALON; MOUSE; MOUSE STRAIN; NEUROMERE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; RHOMBENCEPHALON; TRANSGENE;

ANIMALS; CEREBELLUM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MESENCEPHALON; MICE; MICE, TRANSGENIC; TRANSGENES;

MUS; MUS MUSCULUS;

EID: 73249139732     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.20546     Document Type: Article

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