Ectonucleotidase NTPDase3 is abundant in pancreatic β-cells and regulates glucose-induced insulin secretion

American Journal of Physiology - Endocrinology and Metabolism

Volumn 305, Issue 10, 2013, Pages

  Syed, Samreen K ^a   Kauffman, Audra L ^a   Beavers, Lisa S ^a   Alston, James T ^a   Farb, Thomas B ^a   Ficorilli, James ^a   Marcelo, Marialuisa C ^a   Brenner, Martin B ^a   Bokvist, Krister ^a   Barrett, David G ^a   Efanov, Alexander M ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Adenosine 5' triphosphate; Ectonucleotide triphosphate diphosphohydrolase 3; Insulin secretion; Islets

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA,GAMMA DIBROMOMETHYLENE 6 N,N DIETHYLADENOSINE TRIPHOSPHATE; ECTONUCLEOTIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3; ENZYME; GLUCOSE; PURINERGIC P2Y RECEPTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EXOCYTOSIS; HUMAN; HUMAN CELL; HYDROLYSIS; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

ADENOSINE 5′-TRIPHOSPHATE; ECTONUCLEOTIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3; INSULIN SECRETION; ISLETS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELLS, CULTURED; ENZYME INHIBITORS; GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; MICE, INBRED C57BL; PYROPHOSPHATASES; RNA, MESSENGER; TISSUE DISTRIBUTION;

EID: 84887581829     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00328.2013     Document Type: Article

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