Quercetin modulates OTA-induced oxidative stress and redox signalling in HepG2 cells - Up regulation of Nrf2 expression and down regulation of NF-κB and COX-2

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 1, 2014, Pages 681-692

  Ramyaa, Periasamy ^a   Krishnaswamy, Rajashree ^b   Padma, Viswanadha Vijaya ^a  

^a BHARATHIAR UNIVERSITY   (India)

^b KUMARAGURU COLLEGE OF TECHNOLOGY   (India)

Author keywords

DNA damage; Inflammation; Ochratoxin; Oxidative stress; Quercetin

Indexed keywords

CATALASE; CYCLOOXYGENASE 2; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRITE; OCHRATOXIN; PROTEIN CARBOXYL METHYLTRANSFERASE; QUERCETIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL CULTURE; CELL PROTECTION; CELL VIABILITY; COMET ASSAY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ENZYME ACTIVITY; GENOTOXICITY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LIPID PEROXIDATION; MICRONUCLEUS; NUCLEAR LOCALIZATION SIGNAL; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

2,7-DICHLORODIHYDROFLUORESCEIN DIACETATE; 2,7-DICHLOROFLUORESCEIN; 3,30-DI-HEXYLOXACARBOCYANINE IODIDE; 3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE; 4,4-DIAMIDINO-2-PHENYLINDOLE; ACRIDINE ORANGE/ETHIDIUM BROMIDE; ANALYSIS OF VARIANCE; ANOVA; ANTIOXIDANT RESPONSIVE ELEMENT; AO/EB; ARE; CARBONYL CYANIDE M-CHLOROPHENYLHYDRAZONE; CAT; CATALASE; CBMN; CCCP; COX-2; CYCLOOXYGENASE-2; CYTOKINESIS BLOCK MICRONUCLEUS ASSAY; DAB; DAPI; DCF; DCF-DA; DIAMINOBENZIDINE; DIOC6; DITHIOTHREITOL; DMEM; DNA DAMAGE; DTT; DULBECCO'S MODIFIED EAGLE'S MEDIUM; EDTA; ETHYLENEDIAMINE TETRAACETIC ACID; FBS; FETAL BOVINE SERUM; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE S TRANSFERASE; GPX; GSH; GST; IC20; INDUCIBLE NITRIC OXIDE SYNTHASE; INFLAMMATION; INHIBITORY CONCENTRATION 20; INOS; INTRACELLULAR CALCIUM LEVEL; LACTATE DEHYDROGENASE; LDH; LIPID PEROXIDATION; LIPOPOLYSACCHARIDE; LPO; LPS; MICRONUCLEUS; MN; MTT; NF-ΚB; NITRIC OXIDE; NO; NRF-2; NUCLEAR FACTOR E2 P45-RELATED FACTOR 2; NUCLEAR FACTOR-KAPPA B; OCHRATOXIN; OPT; ORTHO-PHTHALALDEHYDE; OTA; OXIDATIVE STRESS; PCC; PHENYL METHYL SULFONYL FLUORIDE; PMSF; PROTEIN CARBONYL CONTENT; QUERCETIN; REACTIVE OXYGEN SPECIES; ROS; SOD; SUPEROXIDE DISMUTASE; [CA(2+)](I);

ANTIOXIDANTS; APOPTOSIS; BLOTTING, WESTERN; CALCIUM; CALCIUM CHANNEL BLOCKERS; CELL PROLIFERATION; CYCLOOXYGENASE 2; CYTOKINESIS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE; HEP G2 CELLS; HUMANS; LIPID PEROXIDATION; MICRONUCLEUS TESTS; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRITES; OCHRATOXINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN CARBONYLATION; QUERCETIN; REACTIVE OXYGEN SPECIES;

EID: 84887580830     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.10.024     Document Type: Article

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