Development of a poly (ether urethane) system for the controlled release of two novel anti-biofilm agents based on gallium or zinc and its efficacy to prevent bacterial biofilm formation

Journal of Controlled Release

Volumn 172, Issue 3, 2013, Pages 1035-1044

  Ma, Hongyan ^a   Darmawan, Erica T ^a   Zhang, Min ^a   Zhang, Lei ^a   Bryers, James D ^a,b  

^a University of Washington   (United States)

^b University of Washington   (United States)

Author keywords

Anti biofilm biomaterials; Interrupting iron metabolism

Indexed keywords

ANTIBIOTICS; BACTERIA; BIOFILMS; ESTERS; ETHERS; GALLIUM COMPOUNDS; IRON; POLYETHYLENE GLYCOLS; POLYMER FILMS; TARGETED DRUG DELIVERY; ZINC COMPOUNDS;

ANTI-BIOFILM; BIOFILM INFECTIONS; IRON METABOLISM; OPTIMUM FORMULATION; PORE-FORMING AGENTS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS EPIDERMIDIS; SUSTAINED DRUG RELEASE;

CONTROLLED DRUG DELIVERY;

BIOMATERIAL; ENDOTOXIN; GALLIUM; MESOPORPHYRIN; POLY(ETHER URETHANE); POLYMER; PROTOPORPHYRIN; SIDEROPHORE; UNCLASSIFIED DRUG; ZINC; ZINC COMPLEX;

ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BIOFILM; CYTOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; IRON TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS EPIDERMIDIS; SUSTAINED DRUG RELEASE;

ANTI-BIOFILM BIOMATERIALS; INTERRUPTING IRON METABOLISM;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; COORDINATION COMPLEXES; DELAYED-ACTION PREPARATIONS; FEMALE; GALLIUM; HUMANS; MICE; MICE, INBRED C57BL; NIH 3T3 CELLS; POLYURETHANES; PROSTHESIS-RELATED INFECTIONS; PROTOPORPHYRINS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS EPIDERMIDIS; ZINC;

EID: 84887563400     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.10.005     Document Type: Article

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