Polyethylene-glycol suppresses colon cancer and causes dose-dependent regression of azoxymethane-induced aberrant crypt foci in rats

Cancer Research

Volumn 59, Issue 20, 1999, Pages 5143-5147

  Parnaud, Géraldine ^a   Taché, Sylviane ^a   Peiffer, Ginette ^a   Corpet, Denis E ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AZOXYMETHANE; CASEIN; MACROGOL 8000;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BODY WEIGHT; CANCER PREVENTION; CANCER REGRESSION; COLON ADENOMA; COLON CANCER; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FECES; FEMALE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; AZOXYMETHANE; BODY WEIGHT; COLORECTAL NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; FECES; FEMALE; MALE; POLYETHYLENE GLYCOLS; PRECANCEROUS CONDITIONS; RATS; RATS, INBRED F344;

EID: 0032747277     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Potter, J. D., Slattery, M. L., Bostick, R. M., and Gapstur, S. M. Colon cancer: a review of the epidemiology. Epidemiol. Rev., 15: 499-545, 1993.
2. Kelloff, G. J., Boone, C. W., Steele, V. E., Crowell, J. A., Lubet, R. A., Greenwald, P., Hawk, E. T., Fay, J. R., and Sigman, C. C. Mechanistic considerations in the evaluation of chemopreventive data. In: B. W. Stewart, D. McGregor, and P. Kleihues (eds.), Principles of Chemoprevention, pp. 203-214. Lyon, France: IARC, 1996.
3. Langman, M., and Boyle, P. Chemoprevention of colorectal cancer. Gut, 43: 578-585, 1998.
4. Krishnan, K., Ruffin, M. T., and Brenner, D. E. Clinical models of chemoprevention for colon cancer. Hematol. Oncol. Clin. N. Am., 12: 1079-1113, 1998.
5. Klurfeld, D. M. Dietary fiber-mediated mechanisms in carcinogenesis. Cancer Res., 52: 2055s-2059s, 1992.
6. Zoran, D. L., Turner, N. D., Taddeo, S. S., Chapkin, R. S., and Lupton, J. R. Wheat bran diet reduces tumor incidence in a rat model of colon cancer independent of effects on distal luminal butyrate concentrations. J. Nutr., 127: 2217-2225, 1997.
7. Corpet, D. E., Tache, S., and Peiffer, G. Carborundum, a bulk similar to dietary fibers but chemically inert, does not decrease colon carcinogenesis. Cancer Lett., 114: 35-38, 1997.
8. Parnaud, G., Peiffer, G., Taché, S., and Corpet, D. E. Effect of meat (beef, chicken, bacon) on rat colon carcinogenesis. Nutr. Cancer, 32: 165-173, 1998.
9. Lubin, F., Rozen, P., Arieli, B., Farbstein, M., Knaani, Y., Bat, L., and Farbstein, H. Nutritional and lifestyle habits and water-fibers interaction in colorectal adenoma etiology. Cancer Epidemiol. Biomark. Prev., 6: 79-85, 1997.
10. Shannon, J., White, E., Shattuck, A. L., and Potter, J. D. Relationship of food groups and water intake to colon cancer risk. Cancer Epidemiol. Biomark. Prev., 5:495-502, 1996.
11. Attar, A., Lemann, M., Ferguson, A., Halphen, M., Boutron, M. C., Flourie, B., Alix, E., Salmeron, M., Guillemot, F., Chaussade, S., Menard, A. M., Moreau, J., Naudin, G., and Barthet, M. Comparison of a low dose polyethylene glycol electrolyte solution with lactulose for treatment of chronic constipation. Gut, 44: 226-230, 1999.
12. Corpet, D. E., and Parnaud, G. Polyethylene-glycol, a potent suppressor of azoxymethane-induced aberrant crypt foci in rats. Carcinogenesis (Lond.), 20: 915-918, 1999.
13. Corpet, D. E., Stamp, D., Medline, A., Minkin, S., Archer, M. C., and Bruce, W. R. Promotion of colonic microadenoma growth in mice and rats fed cooked sugar or cooked casein and fat. Cancer Res., 50: 6955-6958, 1990.
14. Bird, R. P. Observation and quantification of aberrant crypts in murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett., 37: 147-151, 1987.
15. Zhang, X. M., Stamp, D., Minkin, S., Medline, A., Corpet, D. E., Bruce, W. R., and Archer, M. C. Promotion of aberrant crypt foci and cancer in rat colon by thermolyzed protein. J. Natl. Cancer Inst., 84: 1026-1030, 1992.
16. Pretlow, T. P., Oriordan, M. A., Somich, G. A., Amini, S. B., and Pretlow, T. G. Aberrant crypts correlate with tumor incidence in F344 rats treated with azoxymethane and phytate. Carcinogenesis (Lond.), 13: 1509-1512, 1992.
17. Takayama, T., Katsuki, S., Takahashi, Y., Ohi, M., Nojiri, S., Sakamaki, S., Kato, J., Kogawa, K., Miyake, H., and Niitsu, Y. Aberrant crypt foci of the colon as precursors of adenoma and cancer. N. Engl. J. Med., 339: 1277-1284, 1998.
18. Onogi, N., Okuno, M., Komaki, C., Moriwaki, H., Kawamori, T., Tanaka, T., Mori, H., and Muto, Y. Suppressing effect of perilla oil on azoxymethane-induced foci of colonic aberrant crypts in rats. Carcinogenesis (Lond.), 17: 1291-1296, 1996.
19. Rowland, I. R., Rumney, C. J., Coutts, J. T., and Lievense, L. C. Effect of Bifidobacterium longum and inulin on gut bacterial metabolism and carcinogen-induced aberrant crypt foci in rats. Carcinogenesis (Lond.), 19: 281-285, 1998.
20. Ishizuka, S., and Kasai, T. Inhibitory effect of dietary wheat bran or formation of aberrant crypt foci in rat colon induced by a single injection of 1,2-dimethythydrazine. Biosci. Biotechnol. Biochem., 60: 2084-2085, 1996.
21. Wargovich, M. J., Chen, C. D., Harris, C., Yang, E., and Velasco, M. Inhibition of aberrant crypt growth by non-steroidal anti-inflammatory agents and differentiation agents in the rat colon. Int. J. Cancer. 60: 515-519, 1995.
22. Seraj, M. J., Umemoto, A., Kajikawa, A., Mimura, S., Kinouchi, T., Ohnishi, Y., and Monden, Y. Effects of dietary bile acids on formation of azoxymethane-induced aberrant crypt foci in F344 rats. Cancer Lett., 115: 97-103, 1997.
23. Tao, L. H., Li, K. W., and Pereira, M. A. Chemopreventive agents-induced regression of azoxymethane-induced aberrant crypt foci with the recovery of hexosaminidase activity. Carcinogenesis (Lond.). 18: 1415-1418, 1997.
24. Morishita, Y., Yoshimi, N., Kawabata, K., Matsunaga, K., Sugie, S., Tanaka, T., and Mon, H. Regressive effects of various chemopreventive agents on azoxymethane-induced aberrant crypt foci in the rat colon. Jpn. J. Cancer Res., 88: 815-820, 1997.
25. Kawamori, T., Tanaka, T., Ohnishi, M., Hirose, Y., Nakamura, Y , Satoh, K., Hara, A., and Mori, H. Chemoprevention of azoxymethane-induced colon carcinogenesis by dietary feeding of S-methyl methane thiosulfonate in male F344 rats. Cancer Res., 55: 4053-4058, 1995.
26. Waltenberg, L. W. Inhibition of tumorigenesis in animals. In: B. W. Stewart, D. McGregor, and P. Kleihues (eds.), Principles of Chemoprevention, pp. 151-159. Lyon, France: IARC, 1996.
27. Corpet, D. E., and Chatelin-Pirot, V. Cooked casein promotes colon cancer in rats, may be because of mucosal abrasion. Cancer Lett., 114: 89-90, 1997.
28. McNeil P. L., and Ito, S. Gastrointestinal cell plasma membrane wounding and resealing in vivo. Gastroenterology, 96: 1238-1248, 1989.
29. Togo, T., Alderton, J. M., Bi, G. Q., and Steinhardt, R. A. The mechanism of facilitated cell membrane resealing. J. Cell Sci., 112: 719-731, 1999.