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Volumn 250, Issue , 2013, Pages 384-396

Brain angiotensin regulates iron homeostasis in dopaminergic neurons and microglial cells

Author keywords

Ageing; Dopamine; Microglia; NADPH oxidase; Neuroinflammation; NF kB; Oxidative stress; Parkinson's disease; Renin angiotensin system

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANTIOXIDANT; FERRITIN; FERROPORTIN; I KAPPA B; IRON; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; OXIDOREDUCTASE INHIBITOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSFERRIN RECEPTOR;

EID: 84887543491     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.10.013     Document Type: Article
Times cited : (45)

References (55)
  • 2
    • 18044377401 scopus 로고    scopus 로고
    • NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease
    • Cai H. NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease. Circ. Res. 2005, 96:818-822.
    • (2005) Circ. Res. , vol.96 , pp. 818-822
    • Cai, H.1
  • 3
    • 0034959741 scopus 로고    scopus 로고
    • Characterization of a novel brain-derived microglial cell line isolated from neonatal rat brain
    • Cheepsunthorn P., Radov L., Menzies S., Reid J., Connor J.R. Characterization of a novel brain-derived microglial cell line isolated from neonatal rat brain. Glia 2001, 35:53-62.
    • (2001) Glia , vol.35 , pp. 53-62
    • Cheepsunthorn, P.1    Radov, L.2    Menzies, S.3    Reid, J.4    Connor, J.R.5
  • 4
    • 33947211176 scopus 로고    scopus 로고
    • Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism
    • Collier T.J., Lipton J., Daley B.F., Palfi S., Chu Y., Sortwell C., Collier T.J., Carvey P.M. Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: diminished compensatory mechanisms as a prelude to parkinsonism. Neurobiol. Dis. 2007, 26:56-65.
    • (2007) Neurobiol. Dis. , vol.26 , pp. 56-65
    • Collier, T.J.1    Lipton, J.2    Daley, B.F.3    Palfi, S.4    Chu, Y.5    Sortwell, C.6    Collier, T.J.7    Carvey, P.M.8
  • 5
    • 0029092802 scopus 로고
    • A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains
    • Connor J.R., Snyder B.S., Arosio P., Loeffler D.A., LeWitt P. A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains. J. Neurochem. 1995, 65:717-724.
    • (1995) J. Neurochem. , vol.65 , pp. 717-724
    • Connor, J.R.1    Snyder, B.S.2    Arosio, P.3    Loeffler, D.A.4    LeWitt, P.5
  • 7
    • 0026781572 scopus 로고
    • A novel N18TG2×mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin
    • Crawford G.D., Le W.D., Smith R.G., Lie W.J., Stefani E., Appel S.H. A novel N18TG2×mesencephalon cell hybrid expresses properties that suggest a dopaminergic cell line of substantia nigra origin. J. Neurosci. 1992, 12:3392-3398.
    • (1992) J. Neurosci. , vol.12 , pp. 3392-3398
    • Crawford, G.D.1    Le, W.D.2    Smith, R.G.3    Lie, W.J.4    Stefani, E.5    Appel, S.H.6
  • 9
    • 84858157347 scopus 로고    scopus 로고
    • Iron dysregulation in movement disorders
    • Dusek P., Jankovic J., Le W. Iron dysregulation in movement disorders. Neurobiol. Dis. 2012, 46:1-18.
    • (2012) Neurobiol. Dis. , vol.46 , pp. 1-18
    • Dusek, P.1    Jankovic, J.2    Le, W.3
  • 10
    • 58549098084 scopus 로고    scopus 로고
    • Blood-brain barrier: ageing and microvascular disease-systematic review and meta-analysis
    • Farrall A.J., Wardlaw J.M. Blood-brain barrier: ageing and microvascular disease-systematic review and meta-analysis. Neurobiol. Aging 2009, 30:337-352.
    • (2009) Neurobiol. Aging , vol.30 , pp. 337-352
    • Farrall, A.J.1    Wardlaw, J.M.2
  • 11
    • 0030957951 scopus 로고    scopus 로고
    • Regional distribution of iron, transferrin, ferritin, and oxidatively-modified proteins in young and aged Fischer 344 rat brains
    • Focht S.J., Snyder B.S., Beard J.L., Van Gelder W., Williams L.R., Connor J.R. Regional distribution of iron, transferrin, ferritin, and oxidatively-modified proteins in young and aged Fischer 344 rat brains. Neuroscience 1997, 79:255-261.
    • (1997) Neuroscience , vol.79 , pp. 255-261
    • Focht, S.J.1    Snyder, B.S.2    Beard, J.L.3    Van Gelder, W.4    Williams, L.R.5    Connor, J.R.6
  • 12
    • 71849112978 scopus 로고    scopus 로고
    • Iron as a cause of Parkinson disease - a myth or a well established hypothesis?
    • Friedman A., Galazka-Friedman J., Koziorowski D. Iron as a cause of Parkinson disease - a myth or a well established hypothesis?. Parkinsonism Relat. Disord. 2009, 15(Suppl. 3):S212-S214.
    • (2009) Parkinsonism Relat. Disord. , vol.15 , Issue.SUPPL. 3
    • Friedman, A.1    Galazka-Friedman, J.2    Koziorowski, D.3
  • 13
    • 84857228790 scopus 로고    scopus 로고
    • Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease
    • Garrido-Gil P., Joglar B., Rodriguez-Perez A.I., Guerra M.J., Labandeira-Garcia J.L. Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease. J. Neuroinflammation 2012, 9:38.
    • (2012) J. Neuroinflammation , vol.9 , pp. 38
    • Garrido-Gil, P.1    Joglar, B.2    Rodriguez-Perez, A.I.3    Guerra, M.J.4    Labandeira-Garcia, J.L.5
  • 15
    • 0034677947 scopus 로고    scopus 로고
    • NADPH oxidase: role in cardiovascular biology and disease
    • Griendling K.K., Sorescu D., Ushio-Fukai M. NADPH oxidase: role in cardiovascular biology and disease. Circ. Res. 2000, 86:494-501.
    • (2000) Circ. Res. , vol.86 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 16
    • 0026034279 scopus 로고
    • Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: an X-ray microanalysis
    • Hirsch E.C., Brandel J.P., Galle P., Javoy-Agid F., Agid Y. Iron and aluminum increase in the substantia nigra of patients with Parkinson's disease: an X-ray microanalysis. J. Neurochem. 1991, 56:446-451.
    • (1991) J. Neurochem. , vol.56 , pp. 446-451
    • Hirsch, E.C.1    Brandel, J.P.2    Galle, P.3    Javoy-Agid, F.4    Agid, Y.5
  • 20
    • 62649089147 scopus 로고    scopus 로고
    • The inflammatory response in the MPTP model of Parkinson's disease is mediated by brain angiotensin: relevance to progression of the disease
    • Joglar B., Rodriguez-Pallares J., Rodriguez-Perez A.I., Rey P., Guerra M.J., Labandeira-Garcia J.L. The inflammatory response in the MPTP model of Parkinson's disease is mediated by brain angiotensin: relevance to progression of the disease. J. Neurochem. 2009, 109:656-669.
    • (2009) J. Neurochem. , vol.109 , pp. 656-669
    • Joglar, B.1    Rodriguez-Pallares, J.2    Rodriguez-Perez, A.I.3    Rey, P.4    Guerra, M.J.5    Labandeira-Garcia, J.L.6
  • 21
    • 59249090537 scopus 로고    scopus 로고
    • Glutathione depletion in immortalized midbrain-derived dopaminergic neurons results in increases in the labile iron pool: implications for Parkinson's disease
    • Kaur D., Lee D., Ragapolan S., Andersen J.K. Glutathione depletion in immortalized midbrain-derived dopaminergic neurons results in increases in the labile iron pool: implications for Parkinson's disease. Free Radic. Biol. Med. 2009, 46:593-598.
    • (2009) Free Radic. Biol. Med. , vol.46 , pp. 593-598
    • Kaur, D.1    Lee, D.2    Ragapolan, S.3    Andersen, J.K.4
  • 23
    • 84857373169 scopus 로고    scopus 로고
    • Functional roles of transferrin in the brain
    • Leitner D.F., Connor J.R. Functional roles of transferrin in the brain. Biochim. Biophys. Acta 2012, 1820:393-402.
    • (2012) Biochim. Biophys. Acta , vol.1820 , pp. 393-402
    • Leitner, D.F.1    Connor, J.R.2
  • 24
    • 37349046018 scopus 로고    scopus 로고
    • Nuclear factor-kappaB as a hormonal intracellular signaling molecule: focus on angiotensin II-induced cardiovascular and renal injury
    • Li X.C., Zhuo J.L. Nuclear factor-kappaB as a hormonal intracellular signaling molecule: focus on angiotensin II-induced cardiovascular and renal injury. Curr. Opin. Nephrol. Hypertens. 2008, 17:37-43.
    • (2008) Curr. Opin. Nephrol. Hypertens. , vol.17 , pp. 37-43
    • Li, X.C.1    Zhuo, J.L.2
  • 25
    • 80051660738 scopus 로고    scopus 로고
    • Iron chelation and neuroprotection in neurodegenerative diseases
    • Li X., Jankovic J., Le W. Iron chelation and neuroprotection in neurodegenerative diseases. J. Neural Transm. 2011, 118:473-477.
    • (2011) J. Neural Transm. , vol.118 , pp. 473-477
    • Li, X.1    Jankovic, J.2    Le, W.3
  • 26
    • 51349095669 scopus 로고    scopus 로고
    • Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity
    • Lopes K.O., Sparks D.L., Streit W.J. Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity. Glia 2008, 56:1048-1060.
    • (2008) Glia , vol.56 , pp. 1048-1060
    • Lopes, K.O.1    Sparks, D.L.2    Streit, W.J.3
  • 27
    • 41549133538 scopus 로고    scopus 로고
    • Role and regulation of ferritin H in rotenone-mediated mitochondrial oxidative stress
    • MacKenzie E.L., Ray P.D., Tsuji Y. Role and regulation of ferritin H in rotenone-mediated mitochondrial oxidative stress. Free Radic. Biol. Med. 2008, 44:1762-1771.
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 1762-1771
    • MacKenzie, E.L.1    Ray, P.D.2    Tsuji, Y.3
  • 28
    • 10644232372 scopus 로고    scopus 로고
    • Oxidation-induced ferritin turnover in microglial cells: role of proteasome
    • Mehlhase J., Sandig G., Pantopoulos K., Grune T. Oxidation-induced ferritin turnover in microglial cells: role of proteasome. Free Radic. Biol. Med. 2005, 38:276-285.
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 276-285
    • Mehlhase, J.1    Sandig, G.2    Pantopoulos, K.3    Grune, T.4
  • 29
    • 33746935592 scopus 로고    scopus 로고
    • Ferritin levels in microglia depend upon activation: modulation by reactive oxygen species
    • Mehlhase J., Gieche J., Widmer R., Grune T. Ferritin levels in microglia depend upon activation: modulation by reactive oxygen species. Biochim. Biophys. Acta 2006, 1763:854-859.
    • (2006) Biochim. Biophys. Acta , vol.1763 , pp. 854-859
    • Mehlhase, J.1    Gieche, J.2    Widmer, R.3    Grune, T.4
  • 32
    • 33845693028 scopus 로고    scopus 로고
    • Type 1 angiotensin receptor pharmacology: signaling beyond G proteins
    • Oro C., Qian H., Thomas W.G. Type 1 angiotensin receptor pharmacology: signaling beyond G proteins. Pharmacol. Ther. 2007, 113:210-226.
    • (2007) Pharmacol. Ther. , vol.113 , pp. 210-226
    • Oro, C.1    Qian, H.2    Thomas, W.G.3
  • 36
    • 84856748705 scopus 로고    scopus 로고
    • Different dopaminergic neuroprotection of hormonal replacement therapy in young and aged menopausal rats. Role of the brain angiotensin system
    • Rodriguez-Perez A.I., Valenzuela R., Villar-Cheda B., Guerra M.J., Labandeira-Garcia J.L. Different dopaminergic neuroprotection of hormonal replacement therapy in young and aged menopausal rats. Role of the brain angiotensin system. Brain 2012, 135:124-138.
    • (2012) Brain , vol.135 , pp. 124-138
    • Rodriguez-Perez, A.I.1    Valenzuela, R.2    Villar-Cheda, B.3    Guerra, M.J.4    Labandeira-Garcia, J.L.5
  • 40
    • 67349112729 scopus 로고    scopus 로고
    • Iron, the substantia nigra and related neurological disorders
    • Snyder A.M., Connor J.R. Iron, the substantia nigra and related neurological disorders. Biochim. Biophys. Acta 2009, 1790:606-614.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 606-614
    • Snyder, A.M.1    Connor, J.R.2
  • 46
    • 84861703950 scopus 로고    scopus 로고
    • Involvement of microglial RhoA/Rho-Kinase pathway activation in the dopaminergic neuron death
    • Role of angiotensin via angiotensin type 1 receptors
    • Villar-Cheda B., Dominguez-Meijide A., Joglar B., Rodriguez-Perez A.I., Guerra M.J., Labandeira-Garcia J.L. Involvement of microglial RhoA/Rho-Kinase pathway activation in the dopaminergic neuron death. Neurobiol. Dis. 2012, 47:268-279. Role of angiotensin via angiotensin type 1 receptors.
    • (2012) Neurobiol. Dis. , vol.47 , pp. 268-279
    • Villar-Cheda, B.1    Dominguez-Meijide, A.2    Joglar, B.3    Rodriguez-Perez, A.I.4    Guerra, M.J.5    Labandeira-Garcia, J.L.6
  • 47
    • 81355139581 scopus 로고    scopus 로고
    • Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration
    • Villar-Cheda B., Valenzuela R., Rodriguez-Perez A.I., Guerra M.J., Labandeira-Garcia J.L. Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration. Neurobiol. Aging 2012, 33:204.e1-204.e11.
    • (2012) Neurobiol. Aging , vol.33
    • Villar-Cheda, B.1    Valenzuela, R.2    Rodriguez-Perez, A.I.3    Guerra, M.J.4    Labandeira-Garcia, J.L.5
  • 48
    • 84884901205 scopus 로고    scopus 로고
    • Targeting dysregulation of brain iron homeostasis in Parkinson's disease by iron chelators
    • Weinreb O., Mandel S., Youdim M.B., Amit T. Targeting dysregulation of brain iron homeostasis in Parkinson's disease by iron chelators. Free Radic. Biol. Med. 2013, 62:52-64.
    • (2013) Free Radic. Biol. Med. , vol.62 , pp. 52-64
    • Weinreb, O.1    Mandel, S.2    Youdim, M.B.3    Amit, T.4
  • 49
    • 84870198555 scopus 로고    scopus 로고
    • Importance of the brain Angiotensin system in Parkinson's disease
    • Wright J.W., Harding J.W. Importance of the brain Angiotensin system in Parkinson's disease. Park. Dis. 2012, 2012:860923.
    • (2012) Park. Dis. , vol.2012 , pp. 860923
    • Wright, J.W.1    Harding, J.W.2
  • 50
    • 0028917342 scopus 로고
    • Activated microglia cause superoxide-mediated release of iron from ferritin
    • Yoshida T., Tanaka M., Sotomatsu A., Hirai S. Activated microglia cause superoxide-mediated release of iron from ferritin. Neurosci. Lett. 1995, 190:21-24.
    • (1995) Neurosci. Lett. , vol.190 , pp. 21-24
    • Yoshida, T.1    Tanaka, M.2    Sotomatsu, A.3    Hirai, S.4
  • 52
    • 0035103932 scopus 로고    scopus 로고
    • Iron, neuromelanin and ferritin content in the substantia nigra of normal subjects at different ages: consequences for iron storage and neurodegenerative processes
    • Zecca L., Gallorini M., Schünemann V., Trautwein A.X., Gerlach M., Riederer P., Vezzoni P., Tampellini D. Iron, neuromelanin and ferritin content in the substantia nigra of normal subjects at different ages: consequences for iron storage and neurodegenerative processes. J. Neurochem. 2001, 76:1766-1773.
    • (2001) J. Neurochem. , vol.76 , pp. 1766-1773
    • Zecca, L.1    Gallorini, M.2    Schünemann, V.3    Trautwein, A.X.4    Gerlach, M.5    Riederer, P.6    Vezzoni, P.7    Tampellini, D.8
  • 55
    • 33750535445 scopus 로고    scopus 로고
    • Cellular iron status influences the functional relationship between microglia and oligodendrocytes
    • Zhang X., Surguladze N., Slagle-Webb B., Cozzi A., Connor J.R. Cellular iron status influences the functional relationship between microglia and oligodendrocytes. Glia 2006, 54:795-804.
    • (2006) Glia , vol.54 , pp. 795-804
    • Zhang, X.1    Surguladze, N.2    Slagle-Webb, B.3    Cozzi, A.4    Connor, J.R.5


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