메뉴 건너뛰기




Volumn 51, Issue 11, 2013, Pages 885-894

Molecular regulation of cholesterol metabolism: HDL-based intervention through drugs and diet

Author keywords

Cardiovascular disease; Cholesterol; Drugs interfering with RCT; HDL; Nutrition

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYPOCHOLESTEROLEMIC AGENT;

EID: 84887536452     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (51)
  • 1
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein J L & Brown M S, Regulation of the mevalonate pathway, Nature, 343 (1990) 425.
    • (1990) Nature , vol.343 , pp. 425
    • Goldstein, J.L.1    Brown, M.S.2
  • 3
    • 0037031061 scopus 로고    scopus 로고
    • Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: A randomised placebo-controlled trial
    • Heart protection study collaborative group
    • Heart protection study collaborative group, Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial, Lancet, 360 (2002) 7.
    • (2002) Lancet , vol.360 , pp. 7
  • 4
    • 0025322265 scopus 로고
    • Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit
    • Badimon JJ, Badimon L, & Fuster V, Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit, J Clin Invest, 85 (1990) 1234.
    • (1990) J Clin Invest , vol.85 , pp. 1234
    • Badimon, J.J.1    Badimon, L.2    Fuster, V.3
  • 5
    • 33748194146 scopus 로고    scopus 로고
    • Determinants of plasma HDL concentrations and reverse cholesterol transport
    • Lewis GF, Determinants of plasma HDL concentrations and reverse cholesterol transport, Curr Opin Cardiol, 21 (2006) 345.
    • (2006) Curr Opin Cardiol , vol.21 , pp. 345
    • Lewis, G.F.1
  • 7
    • 0026493679 scopus 로고
    • High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors
    • Bowry V W, Stanley K K, & Stocker R, High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors, Proc Natl Acad Sci 89 (1992) 10316.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 10316
    • Bowry, V.W.1    Stanley, K.K.2    Stocker, R.3
  • 8
    • 1842863230 scopus 로고    scopus 로고
    • Reconstituted high-density lipoprotein inhibits thrombin induced endothelial tissue factor expression through inhibition of RhoA and stimulation of phosphatidylinositol 3-kinase but not Akt/endothelial nitric oxide synthase
    • Viswambharan H, Ming X F, Zhu S, Hubsch A, Lerch P, Vergères G, Rusconi S & Yang Z, Reconstituted high-density lipoprotein inhibits thrombin induced endothelial tissue factor expression through inhibition of RhoA and stimulation of phosphatidylinositol 3-kinase but not Akt/endothelial nitric oxide synthase, Circ Res, 94 (2004) 918.
    • (2004) Circ Res , vol.94 , pp. 918
    • Viswambharan, H.1    Ming, X.F.2    Zhu, S.3    Hubsch, A.4    Lerch, P.5    Vergères, G.6    Rusconi, S.7    Yang, Z.8
  • 9
    • 77953865873 scopus 로고    scopus 로고
    • High-density lipoproteins, platelets and the pathogenesis of atherosclerosis
    • Nofer J R, Brodde M F & Kehrel B E, High-density lipoproteins, platelets and the pathogenesis of atherosclerosis, Clin Exp Pharmacol Physiol, 37 (2010) 726.
    • (2010) Clin Exp Pharmacol Physiol , vol.37 , pp. 726
    • Nofer, J.R.1    Brodde, M.F.2    Kehrel, B.E.3
  • 15
    • 77954455920 scopus 로고    scopus 로고
    • The ectopic F0F1 ATP synthase of rat liver is modulated in acute cholestasis by the inhibitor protein IF1
    • Giorgio V, Bisetto E, Franca R, Harris D A, Passamonti S, & Lippe G, The ectopic F0F1 ATP synthase of rat liver is modulated in acute cholestasis by the inhibitor protein IF1, J Bioenerg Biomembr, 42 (2010) 117.
    • (2010) J Bioenerg Biomembr , vol.42 , pp. 117
    • Giorgio, V.1    Bisetto, E.2    Franca, R.3    Harris, D.A.4    Passamonti, S.5    Lippe, G.6
  • 17
    • 83655167244 scopus 로고    scopus 로고
    • The beta Chain of Cell Surface F0F1 ATPase Modulates ApoA-I & HDL transcytosis through aortic endothelial cells
    • Cavelier C, Ohnsorg P M, Rohrer L, & Eckardstein A V, The beta Chain of Cell Surface F0F1 ATPase Modulates ApoA-I & HDL transcytosis through aortic endothelial cells, Arterioscler Thromb Vasc Biol, 32 (2012) 131.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 131
    • Cavelier, C.1    Ohnsorg, P.M.2    Rohrer, L.3    Eckardstein, A.V.4
  • 20
    • 0019226420 scopus 로고
    • A-I Milano apoprotein: Decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family
    • Franceschini G, Sirtori C R, Capurso A, Weisgraber K H, & Mahley R W, A-I Milano apoprotein: Decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family, J Clin Invest, 66 (1980) 892.
    • (1980) J Clin Invest , vol.66 , pp. 892
    • Franceschini, G.1    Sirtori, C.R.2    Capurso, A.3    Weisgraber, K.H.4    Mahley, R.W.5
  • 21
    • 84887533301 scopus 로고    scopus 로고
    • Up-regulation of reverse cholesterol transport key players & rescue from global inflammation by ApoA-I(Milano)
    • Cimmino G, Ibanez B, Vilahur G, Speidl W S, Fuster V, Badimon L & Badimon J J, Up-regulation of reverse cholesterol transport key players & rescue from global inflammation by ApoA-I(Milano), J Cell Mol Med, 133 (2009) 226.
    • (2009) J Cell Mol Med , vol.133 , pp. 226
    • Cimmino, G.1    Ibanez, B.2    Vilahur, G.3    Speidl, W.S.4    Fuster, V.5    Badimon, L.6    Badimon, J.J.7
  • 24
    • 41149128233 scopus 로고    scopus 로고
    • Surrogate end points & FDA approval: A tale of 2 lipid-altering drugs
    • Psaty B M & Lumley T, Surrogate end points & FDA approval: a tale of 2 lipid-altering drugs, JAMA, 299 (2008) 1474.
    • (2008) JAMA , vol.299 , pp. 1474
    • Psaty, B.M.1    Lumley, T.2
  • 25
    • 74549148035 scopus 로고    scopus 로고
    • Cholesteryl ester transferprotein: At the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors
    • Chapman M J, Le Goff W, Guerin M, & Kontush A, Cholesteryl ester transferprotein: At the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors, Eur Heart J, 31 (2010) 49.
    • (2010) Eur Heart J , vol.31 , pp. 49
    • Chapman, M.J.1    Le Goff, W.2    Guerin, M.3    Kontush, A.4
  • 28
    • 1042286477 scopus 로고    scopus 로고
    • Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: Effects on lipid homeostasis, inflammation, and atherosclerosis
    • Ricote M, Valledor A F, & Glass C K, Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis, Arterioscler Thromb Vasc Biol, 24 (2004) 230.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 230
    • Ricote, M.1    Valledor, A.F.2    Glass, C.K.3
  • 29
    • 0038614979 scopus 로고    scopus 로고
    • Stimulation of cholesterol excretion by the liver × receptor agonist requires ATP-binding cassette transporters G5 and G8
    • Yu L, York J, von Bergmann K, Lutjohann D, Cohen J C, & Hobbs H H, Stimulation of cholesterol excretion by the liver × receptor agonist requires ATP-binding cassette transporters G5 and G8, J Biol Chem, 278 (2003) 15565.
    • (2003) J Biol Chem , vol.278 , pp. 15565
    • Yu, L.1    York, J.2    von Bergmann, K.3    Lutjohann, D.4    Cohen, J.C.5    Hobbs, H.H.6
  • 32
    • 79953045767 scopus 로고    scopus 로고
    • A novel potent synthetic steroidal liver × receptor agonist lowers plasma cholesterol and triglycerides and reduces atherosclerosis in LDLR(-/-) mice
    • Peng D, Hiipakka R A, Xie J T, Dai Q, Kokontis J M, Reardon C A, Getz G S, & Liao S, A novel potent synthetic steroidal liver × receptor agonist lowers plasma cholesterol and triglycerides and reduces atherosclerosis in LDLR(-/-) mice, Br J Pharmacol, 162 (2011) 1792.
    • (2011) Br J Pharmacol , vol.162 , pp. 1792
    • Peng, D.1    Hiipakka, R.A.2    Xie, J.T.3    Dai, Q.4    Kokontis, J.M.5    Reardon, C.A.6    Getz, G.S.7    Liao, S.8
  • 33
    • 33847006599 scopus 로고    scopus 로고
    • The liver X receptor (LXR) & hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR
    • Cha J Y & Repa J J, The liver X receptor (LXR) & hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR, J Biol Chem, 282 (2007) 743.
    • (2007) J Biol Chem , vol.282 , pp. 743
    • Cha, J.Y.1    Repa, J.J.2
  • 34
    • 0037155049 scopus 로고    scopus 로고
    • Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice
    • Braun A, Trigatti B L, Post M J, Sato K, Simons M, Edelberg J M, Rosenberg R D, Schrenzel M, & Krieger M, Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice, Circ Res, 90 (2002) 270.
    • (2002) Circ Res , vol.90 , pp. 270
    • Braun, A.1    Trigatti, B.L.2    Post, M.J.3    Sato, K.4    Simons, M.5    Edelberg, J.M.6    Rosenberg, R.D.7    Schrenzel, M.8    Krieger, M.9
  • 36
    • 44649111054 scopus 로고    scopus 로고
    • Niacin inhibits surface expression of ATP synthase beta chain in HepG2 cells: Implications for raising HDL
    • Zhang L H, Kamanna V S, Zhang M C & Kashyap M L, Niacin inhibits surface expression of ATP synthase beta chain in HepG2 cells: implications for raising HDL, J Lip Res, 49 (2008) 1195.
    • (2008) J Lip Res , vol.49 , pp. 1195
    • Zhang, L.H.1    Kamanna, V.S.2    Zhang, M.C.3    Kashyap, M.L.4
  • 37
    • 79952297157 scopus 로고    scopus 로고
    • Biliary sterol secretion is required for functional in vivo reverse cholesterol transport in mice
    • Nijstad N, Gautier T, Briand F, Rader D J, & Tietge U J F, biliary sterol secretion is required for functional in vivo reverse cholesterol transport in mice, Gastroenterol, 140 (2011) 1043.
    • (2011) Gastroenterol , vol.140 , pp. 1043
    • Nijstad, N.1    Gautier, T.2    Briand, F.3    Rader, D.J.4    Tietge, U.J.F.5
  • 38
    • 34548492458 scopus 로고    scopus 로고
    • Direct intestinal cholesterol secretion contributes significantly to total fecal neutral sterol excretion in mice
    • van der Velde A E, Vrins C L, & van den Oever K, Direct intestinal cholesterol secretion contributes significantly to total fecal neutral sterol excretion in mice, Gastroenterol, 133 (2007) 967.
    • (2007) Gastroenterol , vol.133 , pp. 967
    • van der Velde, A.E.1    Vrins, C.L.2    van den Oever, K.3
  • 39
    • 84860687550 scopus 로고    scopus 로고
    • Niemann-Pick C1-Like 1 and cholesterol uptake
    • Wang L Juan & Song B L, Niemann-Pick C1-Like 1 and cholesterol uptake, Biochim Biophys Acta, 1821 (2012) 964.
    • (2012) Biochim Biophys Acta , vol.1821 , pp. 964
    • Wang, L.J.1    Song, B.L.2
  • 40
    • 84887520225 scopus 로고    scopus 로고
    • NIH Publication No. 02-5215, September
    • NIH Publication No. 02-5215, September 2002.
    • (2002)
  • 41
    • 0036147485 scopus 로고    scopus 로고
    • Effects of plant stanol esters supplied in low-fat yoghurt on serum lipids and lipoproteins, non-cholesterol sterols and fat soluble antioxidant concentrations
    • Mensink R P, Ebbing S, Lindhout M, Plat J, & van Heugten M M, Effects of plant stanol esters supplied in low-fat yoghurt on serum lipids and lipoproteins, non-cholesterol sterols and fat soluble antioxidant concentrations, Atherosclerosis, 160 (2002) 205.
    • (2002) Atherosclerosis , vol.160 , pp. 205
    • Mensink, R.P.1    Ebbing, S.2    Lindhout, M.3    Plat, J.4    van Heugten, M.M.5
  • 42
    • 0042206849 scopus 로고    scopus 로고
    • Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels
    • Katan M B, Grundy S M, Jones P, Law M, Miettinen T A, & Paoletti R, Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels, Mayo Clin Proc, 78 (2003) 965.
    • (2003) Mayo Clin Proc , vol.78 , pp. 965
    • Katan, M.B.1    Grundy, S.M.2    Jones, P.3    Law, M.4    Miettinen, T.A.5    Paoletti, R.6
  • 44
    • 84863557427 scopus 로고    scopus 로고
    • Phytosterols Reduce Cholesterol Absorption byInhibition of 27-Hydroxycholesterol Generation,Liver X Receptor a Activation, and Expression of the Basolateral Sterol Exporter ATP-Binding Cassette A1 in Caco-2 Enterocytes
    • Brauner R, Johannes C, Ploessl F, Bracher F, & Lorenz R L, Phytosterols Reduce Cholesterol Absorption byInhibition of 27-Hydroxycholesterol Generation,Liver X Receptor a Activation, and Expression of the Basolateral Sterol Exporter ATP-Binding Cassette A1 in Caco-2 Enterocytes, J Nutr, 142 (2012) 981.
    • (2012) J Nutr , vol.142 , pp. 981
    • Brauner, R.1    Johannes, C.2    Ploessl, F.3    Bracher, F.4    Lorenz, R.L.5
  • 45
    • 84874461894 scopus 로고    scopus 로고
    • Probiotics-interactions with bile acids and impact on cholesterol metabolism
    • Pavlović N, Stankov K, & Mikov M, Probiotics-interactions with bile acids and impact on cholesterol metabolism, Appl Biochem Biotechnol, 12 (2010) 9904.
    • (2010) Appl Biochem Biotechnol , vol.12 , pp. 9904
    • Pavlović, N.1    Stankov, K.2    Mikov, M.3
  • 46
    • 84887507719 scopus 로고    scopus 로고
    • WHO, Health and Nutritional Properties of Probiotics in Food including Powder Milk with Live Lactic Acid Bacteria
    • WHO, Health and Nutritional Properties of Probiotics in Food including Powder Milk with Live Lactic Acid Bacteria, 2001.
    • (2001)
  • 48
    • 77954803814 scopus 로고    scopus 로고
    • Cholesterol-lowering effects of probiotics & prebiotics: A review of in vivo and in vitro findings
    • Ooi L G & Liong M T, Cholesterol-lowering effects of probiotics & prebiotics: A review of in vivo and in vitro findings, Int J Mol Sci, 11 (2010) 2499.
    • (2010) Int J Mol Sci , vol.11 , pp. 2499
    • Ooi, L.G.1    Liong, M.T.2
  • 50
    • 77649195167 scopus 로고    scopus 로고
    • The probiotic Lactobacillus acidophilus reduces cholesterol absorption through the downregulation of Niemann-Pick C1-like 1 in Caco-2 cells
    • Huang Y & Zheng Y, The probiotic Lactobacillus acidophilus reduces cholesterol absorption through the downregulation of Niemann-Pick C1-like 1 in Caco-2 cells, Br J Nutr, 103 (2010) 473.
    • (2010) Br J Nutr , vol.103 , pp. 473
    • Huang, Y.1    Zheng, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.