메뉴 건너뛰기




Volumn 24, Issue 5, 2013, Pages 617-630

Requirement for Interaction of PI3-Kinase p110α with RAS in Lung Tumor Maintenance

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BYL 719; CARBOPLATIN; CRE RECOMBINASE; MITOGEN ACTIVATED PROTEIN KINASE; P110 ALPHA PROTEIN; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PICTILISIB; PROTEIN P110; PROTEIN S6; RAS PROTEIN; TAMOXIFEN; TRAMETINIB; UNCLASSIFIED DRUG;

EID: 84887532497     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2013.09.012     Document Type: Article
Times cited : (143)

References (34)
  • 1
    • 0033574429 scopus 로고    scopus 로고
    • Proliferative defect and embryonic lethality in mice homozygous for adeletion in the p110alpha subunit of phosphoinositide 3-kinase
    • Bi L., Okabe I., Bernard D.J., Wynshaw-Boris A., Nussbaum R.L. Proliferative defect and embryonic lethality in mice homozygous for adeletion in the p110alpha subunit of phosphoinositide 3-kinase. J.Biol. Chem. 1999, 274:10963-10968.
    • (1999) J.Biol. Chem. , vol.274 , pp. 10963-10968
    • Bi, L.1    Okabe, I.2    Bernard, D.J.3    Wynshaw-Boris, A.4    Nussbaum, R.L.5
  • 2
    • 33644513730 scopus 로고    scopus 로고
    • Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
    • Cully M., You H., Levine A.J., Mak T.W. Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat. Rev. Cancer 2006, 6:184-192.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 184-192
    • Cully, M.1    You, H.2    Levine, A.J.3    Mak, T.W.4
  • 3
    • 84876424760 scopus 로고    scopus 로고
    • Macrophage regulation of tumor responses to anticancer therapies
    • De Palma M., Lewis C.E. Macrophage regulation of tumor responses to anticancer therapies. Cancer Cell 2013, 23:277-286.
    • (2013) Cancer Cell , vol.23 , pp. 277-286
    • De Palma, M.1    Lewis, C.E.2
  • 4
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • Downward J. Targeting RAS signalling pathways in cancer therapy. Nat. Rev. Cancer 2003, 3:11-22.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 11-22
    • Downward, J.1
  • 10
    • 77956280407 scopus 로고    scopus 로고
    • PIK3CA mutation uncouples tumor growth and cyclin D1 regulation from MEK/ERK and mutant KRAS signaling
    • Halilovic E., She Q.B., Ye Q., Pagliarini R., Sellers W.R., Solit D.B., Rosen N. PIK3CA mutation uncouples tumor growth and cyclin D1 regulation from MEK/ERK and mutant KRAS signaling. Cancer Res. 2010, 70:6804-6814.
    • (2010) Cancer Res. , vol.70 , pp. 6804-6814
    • Halilovic, E.1    She, Q.B.2    Ye, Q.3    Pagliarini, R.4    Sellers, W.R.5    Solit, D.B.6    Rosen, N.7
  • 19
    • 27644556527 scopus 로고    scopus 로고
    • Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance
    • Lim K.H., Counter C.M. Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance. Cancer Cell 2005, 8:381-392.
    • (2005) Cancer Cell , vol.8 , pp. 381-392
    • Lim, K.H.1    Counter, C.M.2
  • 22
    • 84877630250 scopus 로고    scopus 로고
    • Coordinate direct input of both KRAS and IGF1 receptor to activation of PI 3-kinase in KRAS mutant lung cancer
    • Molina-Arcas M., Hancock D.C., Sheridan C., Kumar M.S., Downward J. Coordinate direct input of both KRAS and IGF1 receptor to activation of PI 3-kinase in KRAS mutant lung cancer. Cancer Discov. 2013, 3:548-563.
    • (2013) Cancer Discov. , vol.3 , pp. 548-563
    • Molina-Arcas, M.1    Hancock, D.C.2    Sheridan, C.3    Kumar, M.S.4    Downward, J.5
  • 23
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard J.W. Tumour-educated macrophages promote tumour progression and metastasis. Nat. Rev. Cancer 2004, 4:71-78.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 25
    • 34250694086 scopus 로고    scopus 로고
    • Vagaries of conditional gene targeting
    • Schmidt-Supprian M., Rajewsky K. Vagaries of conditional gene targeting. Nat. Immunol. 2007, 8:665-668.
    • (2007) Nat. Immunol. , vol.8 , pp. 665-668
    • Schmidt-Supprian, M.1    Rajewsky, K.2
  • 27
    • 77954296394 scopus 로고    scopus 로고
    • 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors
    • She Q.B., Halilovic E., Ye Q., Zhen W., Shirasawa S., Sasazuki T., Solit D.B., Rosen N. 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors. Cancer Cell 2010, 18:39-51.
    • (2010) Cancer Cell , vol.18 , pp. 39-51
    • She, Q.B.1    Halilovic, E.2    Ye, Q.3    Zhen, W.4    Shirasawa, S.5    Sasazuki, T.6    Solit, D.B.7    Rosen, N.8
  • 29
    • 77249100829 scopus 로고    scopus 로고
    • Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation
    • Sopasakis V.R., Liu P., Suzuki R., Kondo T., Winnay J., Tran T.T., Asano T., Smyth G., Sajan M.P., Farese R.V., et al. Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation. Cell Metab. 2010, 11:220-230.
    • (2010) Cell Metab. , vol.11 , pp. 220-230
    • Sopasakis, V.R.1    Liu, P.2    Suzuki, R.3    Kondo, T.4    Winnay, J.5    Tran, T.T.6    Asano, T.7    Smyth, G.8    Sajan, M.P.9    Farese, R.V.10
  • 32
    • 73649112422 scopus 로고    scopus 로고
    • Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation
    • Takahashi H., Ogata H., Nishigaki R., Broide D.H., Karin M. Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. Cancer Cell 2010, 17:89-97.
    • (2010) Cancer Cell , vol.17 , pp. 89-97
    • Takahashi, H.1    Ogata, H.2    Nishigaki, R.3    Broide, D.H.4    Karin, M.5
  • 33
    • 7944238044 scopus 로고    scopus 로고
    • Somatic alterations in the human cancer genome
    • Weir B., Zhao X., Meyerson M. Somatic alterations in the human cancer genome. Cancer Cell 2004, 6:433-438.
    • (2004) Cancer Cell , vol.6 , pp. 433-438
    • Weir, B.1    Zhao, X.2    Meyerson, M.3
  • 34
    • 33750826279 scopus 로고    scopus 로고
    • The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation
    • Zhao J.J., Cheng H., Jia S., Wang L., Gjoerup O.V., Mikami A., Roberts T.M. The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation. Proc. Natl. Acad. Sci. USA 2006, 103:16296-16300.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16296-16300
    • Zhao, J.J.1    Cheng, H.2    Jia, S.3    Wang, L.4    Gjoerup, O.V.5    Mikami, A.6    Roberts, T.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.