Endogenous PI3K/Akt and NMDAR act independently in the regulation of CREB activity in lumbosacral spinal cord in cystitis

Experimental Neurology

Volumn 250, Issue , 2013, Pages 366-375

  Kay, Jarren C ^a   Xia, Chun Mei ^a   Liu, Miao ^a   Shen, Shanwei ^a   Yu, Sharon J ^a   Chung, Chulwon ^a   Qiao, Li Ya ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; Central sensitization; CREB; NMDAR; Spinal cord

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 2 MORPHOLINO 8 PHENYLCHROMONE; CALCITONIN GENE RELATED PEPTIDE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOPHOSPHAMIDE; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM SENSITIZATION; CONTROLLED STUDY; CYSTITIS; ENZYME ACTIVITY; EX VIVO STUDY; IN VIVO STUDY; LUMBOSACRAL SPINAL CORD; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM; SPINAL CORD;

AKT; CENTRAL SENSITIZATION; CREB; NMDAR; SPINAL CORD;

ANIMALS; BLOTTING, WESTERN; CENTRAL NERVOUS SYSTEM SENSITIZATION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYSTITIS; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; LUMBOSACRAL REGION; MALE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION; SPINAL CORD;

EID: 84887531098     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.10.015     Document Type: Article

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