Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 46, 2013, Pages 18698-18703

  George, Lynn ^a,b   Chaverra, Marta ^a   Wolfe, Lindsey ^a   Thorne, Julian ^a   Close Davis, Mattheson ^a   Eibs, Amy ^a   Riojas, Vickie ^a   Grindeland, Andrea ^c   Orr, Miranda ^c   Carlson, George A ^c   Lefcort, Frances ^a  

^a MONTANA STATE UNIVERSITY   (United States)

^b MONTANA STATE UNIVERSITY BILLINGS   (United States)

^c MCLAUGHLIN RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; INHIBITOR OF KAPPA B KINASE COMPLEX ASSOCIATED PROTEIN; NERVE GROWTH FACTOR; NEUROTROPHIN 3 RECEPTOR; PROTEIN P53; PROTEIN TYROSINE KINASE A; TRANSCRIPTION FACTOR PAX3; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG;

ADRENAL MEDULLA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DORSAL ROOT; DYSAUTONOMIA; EMBRYO; EMBRYONIC STEM CELL; MITOSIS; MOUSE; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NERVOUS SYSTEM DEVELOPMENT; NEURAL CREST CELL; NEURAL STEM CELL; NEUROPATHOLOGY; NONHUMAN; PAIN RECEPTOR; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SYMPATHETIC GANGLION; SYMPATHETIC NERVE CELL; THERMORECEPTOR;

ANIMALS; APOPTOSIS; CARRIER PROTEINS; CELL LINEAGE; DISEASE MODELS, ANIMAL; DNA PRIMERS; DYSAUTONOMIA, FAMILIAL; FACIAL BONES; GENE DELETION; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MUTAGENESIS; NEURAL CREST; PAIRED BOX TRANSCRIPTION FACTORS; PERIPHERAL NERVOUS SYSTEM;

EID: 84887496750     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1308596110     Document Type: Article

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