Deletion of exon 20 of the familial dysautonomia gene ikbkap in mice causes developmental delay, cardiovascular defects, and early embryonic lethality

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Dietrich, Paula ^a   Yue, Junming ^a   Shuyu, E ^a   Dragatsis, Ioannis ^a  

^a UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B KINASE; MESSENGER RNA; CARRIER PROTEIN; IKBKAP PROTEIN, MOUSE;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR MALFORMATION; CENTRAL NERVOUS SYSTEM MALFORMATION; CONTROLLED STUDY; DEVELOPMENTAL GENE; DYSAUTONOMIA; EMBRYO; EXON; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC ANALYSIS; HEART FAILURE; HISTOPATHOLOGY; HOMOLOGOUS RECOMBINATION; HOMOZYGOSITY; IKBKAP GENE; INTRAUTERINE GROWTH RETARDATION; LETHALITY; MORPHOGENESIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHENOTYPE; ANIMAL; DEVELOPMENTAL DISORDER; FEMALE; FETUS DEATH; GENETICS; MUTATION; PHYSIOLOGY; PREGNANCY; PREGNANCY COMPLICATION;

ANIMALIA; MUS;

ANIMALS; CARDIOVASCULAR ABNORMALITIES; CARRIER PROTEINS; DEVELOPMENTAL DISABILITIES; DYSAUTONOMIA, FAMILIAL; EXONS; FEMALE; FETAL DEATH; MICE; MUTATION; PREGNANCY; PREGNANCY COMPLICATIONS;

EID: 80055061041     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027015     Document Type: Article

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