Loss of mouse ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP

Molecular and Cellular Biology

Volumn 29, Issue 3, 2009, Pages 736-744

  Chen, Yei Tsung ^a   Hims, Matthew M ^a   Shetty, Ranjit S ^a   Mull, James ^a   Liu, Lijuan ^a   Leyne, Maire ^a   Slaugenhaupt, Susan A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B KINASE; I KAPPA B KINASE ASSOCIATED PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; IKBKAP PROTEIN, HUMAN; IKBKAP PROTEIN, MOUSE; PROTEIN SUBUNIT;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EMBRYO DEVELOPMENT; GASTRULATION; HUMAN; IN VIVO STUDY; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; YOLK SAC; ANIMAL; ANIMAL EMBRYO; BLOOD VESSEL; CONGENITAL MALFORMATION; CROSS BREEDING; EMBRYO DEATH; EMBRYO MEMBRANE; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC TRANSCRIPTION; GENETICS; HETEROZYGOTE; MALE; METABOLISM; MOUSE MUTANT; PATHOLOGY; PRENATAL DEVELOPMENT; TRANSGENE;

ANIMALS; BLOOD VESSELS; CARRIER PROTEINS; CROSSES, GENETIC; EMBRYO LOSS; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; EXTRAEMBRYONIC MEMBRANES; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE TARGETING; HETEROZYGOTE; HUMANS; MALE; MICE; MICE, KNOCKOUT; PROTEIN SUBUNITS; TRANSCRIPTION, GENETIC; TRANSGENES;

EID: 59249093238     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01313-08     Document Type: Article

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