Preferential Binding to Elk-1 by SLE-Associated IL10 Risk Allele Upregulates IL10 Expression

PLoS Genetics

Volumn 9, Issue 10, 2013, Pages

  Sakurai, Daisuke ^a   Zhao, Jian ^a   Deng, Yun ^a   Kelly, Jennifer A ^b   Brown, Elizabeth E ^c,d   Harley, John B ^e,f   Bae, Sang Cheol ^g   Alarcn Riquelme, Marta E ^b,h   Edberg, Jeffrey C ^c   Kimberly, Robert P ^c   Ramsey Goldman, Rosalind ⁱ   Petri, Michelle A ^j   Reveille, John D ^k   Vilá, Luis M ^l   Alarcón, Graciela S ^c   Kaufman, Kenneth M ^e,f   Vyse, Timothy J ^m   Jacob, Chaim O ⁿ   Gaffney, Patrick M ^b   Sivils, Kathy Moser ^b   James, Judith A ^b,o   Kamen, Diane L ^p   Gilkeson, Gary S ^p   Niewold, Timothy B ^q   Merrill, Joan T ^b   Scofield, R Hal ^b,o,r   Criswell, Lindsey A ^s   Stevens, Anne M ^t   Boackle, Susan A ^u   Kim, Jae Hoon ^g   Choi, Jiyoung ^g   Pons Estel, Bernardo A ^v   Freedman, Barry I ^w   Anaya, Juan Manuel ^x   Martin, Javier ^y,ac   Yu, C Yung ^z   Chang, Deh Ming ^aa   Song, Yeong Wook ^ab   Langefeld, Carl D ^w   Chen, Weiling ^a   Grossman, Jennifer M ^a   Cantor, Rita M ^a   Hahn, Bevra H ^a   Tsao, Betty P ^a   Frostegård, Johan ^ac   Truedsson, Lennart ^ac   de Ramón, Enrique ^ac   Sabio, José M ^ac   Ortego Centeno, Norberto ^ac   CAllejas, José Luis ^ac   González Escribano, María F ^ac   Sánchez Román, Julio ^ac   D'Alfonso, Sandra ^ac   Migliarese, Sergio ^ac   Sebastiani, Gian Domenico ^ac   Galeazzi, Mauro ^ac   Witte, Torsten ^ac   Lauwerys, Bernard R ^ac   Endreffy, Emoke ^ac   Kovács, László ^ac   Vasconcelos, Carlos ^ac   da Silva, Berta Martins ^ac   Scherbarth, Hugo R ^ac,ad   Marino, Pilar C ^ac,ad   Motta, Estela L ^ac,ad   Gamron, Susana ^ac,ae   Drenkard, Cristina ^ac,ae   Menso, Emilia ^ac,ae   Allievi, Alberto ^ac,af   Tate, Guillermo A ^ac,af   Presas, Jose L ^ac,ag   Palatnik, Simon A ^ac,ah   Abdala, Marcelo ^ac,ah   Bearzotti, Mariela ^ac,ah   Alvarellos, Alejandro ^ac,ai   Caeiro, Francisco ^ac,ai   Bertoli, Ana ^ac,ai   Paira, Sergio ^ac,aj   Roverano, Susana ^ac,aj   Graf, Cesar E ^ac,ak   Bertero, Estela ^ac,ak   Caprarulo, Cesar ^ac,al   Buchanan, Griselda ^ac,al   Guillerón, Carolina ^ac,am   Grimaudo, Sebastian ^ac,am   Manni, Jorge ^ac,am   Catoggio, Luis J ^ac,an   Soriano, Enrique R ^ac,an   Santos, Carlos D ^ac,an   Prigione, Cristina ^ac,ao   Ramos, Fernando A ^ac,ao   Navarro, Sandra M ^ac,ao   Berbotto, Guillermo A ^ac,ap   Jorfen, Marisa ^ac,ap   Romero, Elisa J ^ac,ap   Garcia, Mercedes A ^ac,aq   Marcos, Juan C ^ac,aq   Marcos, Ana I ^ac,aq   Perandones, Carlos E ^ac,ar   Eimon, Alicia ^ac,ar   Parque, Sanatorio ^ac   Battagliotti, Cristina G ^ac,as   Acevedo, Eduardo ^ac   Cucho, Mariano ^ac   de la Torre, Ignacio García ^ac   Ríos, Mario Cardiel ^ac   Moctezuma, José Francisco ^ac   Ceceña, Marco Maradiaga ^ac   more..

^a UNIVERSITY OF CALIFORNIA   (United States)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^c University of Alabama at Birmingham   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

^g Hanyang University Hospital for Rheumatic Diseases   (South Korea)

^h UNIVERSITY OF GRANADA   (Spain)

ⁱ NORTHWESTERN UNIVERSITY   (United States)

^j JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF TEXAS   (United States)

^l UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^m KING'S COLLEGE LONDON   (United Kingdom)

ⁿ UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^o UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^p MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^q MAYO CLINIC   (United States)

^r VETERANS AFFAIRS MEDICAL CENTER   (United States)

^s UNIVERSITY OF CALIFORNIA   (United States)

^t UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^u UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^v Sanatorio Parque   (Argentina)

^w WAKE FOREST SCHOOL OF MEDICINE   (United States)

^x UNIVERSIDAD DEL ROSARIO   (Colombia)

^y INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^z OHIO STATE UNIVERSITY   (United States)

^aa NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^ab Seoul National University   (South Korea)

^ac Organización Médica de Investigación ^*

^ad Hospital Interzonal General de Agudos Dr Oscar Alende   (Argentina)

^ae Universidad Nacional de Córdoba   (Argentina)

^af Organización Médica de Investigación   (Argentina)

^ag HOSPITAL JUAN A FERNÁNDEZ   (Argentina)

^ah UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

^ai Privado Hospital   (Argentina)

^aj Hospital Jose M Cullen   (Argentina)

^ak HOSPITAL SAN MARTÍN   (Argentina)

^al Hospital Felipe Heras   (Argentina)

^am INSTITUTO DE INVESTIGACIONES MÉDICAS ALFREDO LANARI   (Argentina)

^an HOSPITAL ITALIANO DE BUENOS AIRES   (Argentina)

^ao Hospital Provincial de Rosario   (Argentina)

^ap Hospital Eva Peron   (Argentina)

^aq Hospital Interzonal General de Agudos de La Plata   (Argentina)

^ar CEMIC   (Argentina)

^as 'O Alassia' Children's Hospital   (Argentina)

more..

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 20; INTERLEUKIN 24; TRANSCRIPTION FACTOR ELK 1;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE PREDISPOSITION; DOWN REGULATION; GENE; GENE CLUSTER; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; IL10 GENE; INTRON; MAJOR CLINICAL STUDY; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; UPREGULATION;

ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; ETS-DOMAIN PROTEIN ELK-1; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPLOTYPES; HISPANIC AMERICANS; HUMANS; INTERLEUKIN-10; INTRONS; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; UP-REGULATION;

EID: 84887310358     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003870     Document Type: Article

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