A neurotoxic phosphoform of Elk-1 associates with inclusions from multiple neurodegenerative diseases

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Sharma, Anup ^a   Callahan, Linda M ^b   Sul, Jai Yoon ^a   Kim, Tae Kyung ^a   Barrett, Lindy ^c   Kim, Minsun ^d   Powers, James M ^b   Federoff, Howard ^e   Eberwine, James ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d Wonkwang University School of Medicine   (South Korea)

^e GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR ELK 1; THREONINE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL COMPARTMENTALIZATION; CELL INCLUSION; CELL NUCLEUS; DEGENERATIVE DISEASE; DENDRITE; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; LEWY BODY; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; AGED; ANIMAL; BINDING SITE; CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DIFFUSE LEWY BODY DISEASE; FEMALE; GENETIC TRANSFECTION; GENETICS; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; NERVE CELL; PATHOLOGY; PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANIMALS; BINDING SITES; CELLS, CULTURED; ETS-DOMAIN PROTEIN ELK-1; FEMALE; HUMANS; HUNTINGTON DISEASE; IMMUNOHISTOCHEMISTRY; INCLUSION BODIES; LEWY BODY DISEASE; MALE; MICROSCOPY, CONFOCAL; MIDDLE AGED; MUTAGENESIS, SITE-DIRECTED; NEURODEGENERATIVE DISEASES; NEURONS; PHOSPHORYLATION; RATS; THREONINE; TRANSFECTION;

EID: 77749322374     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009002     Document Type: Article

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