Flavonoids from the leaves of Carya cathayensis Sarg. inhibit vascular endothelial growth factor-induced angiogenesis

Fitoterapia

Volumn 92, Issue 1, 2014, Pages 34-40

  Tian, Sha Sha ^a   Jiang, Fu Sheng ^a   Zhang, Kun ^a   Zhu, Xue Xin ^a   Jin, Bo ^a   Lu, Jin Jian ^b   Ding, Zhi Shan ^a  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b University of Macau   (Macao)

Author keywords

Angiogenesis; Flavonoids; Migration; Proliferation; VEGF

Indexed keywords

ANGIOGENESIS INHIBITOR; CARDAMONIN; CHALCONE; CHRYSIN; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PINOCEMBRINE; PINOSTROBIN; PROTEIN KINASE B; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN; WOGONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CARYA; CARYA CATHAYENSIS; CELL CULTURE; CELL MIGRATION; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHINA; CHINESE HERB; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; EX VIVO STUDY; HUMAN; HUMAN CELL; MALE; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR RING; WOUND HEALING;

CARYA CATHAYENSIS;

ANGIOGENESIS; FLAVONOIDS; MIGRATION; PROLIFERATION; VEGF;

ANGIOGENESIS INHIBITORS; ANIMALS; CARYA; CELL MOVEMENT; CELL PROLIFERATION; CHALCONES; DRUGS, CHINESE HERBAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVANONES; FLAVONOIDS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MICE; PLANT LEAVES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84887254423     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2013.09.016     Document Type: Article

References (25)

1. J. Jiang, M. Yan, J.L. Mehta, and C. Hu Angiogenesis is a link between atherosclerosis and tumorigenesis: role of lox-1 Cardiovasc Drugs Ther 25 2011 461 468
2. J.C. Sluimer, and M.J. Daemen Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis J Pathol 218 2009 7 29
3. Z. Szekanecz, and A.E. Koch Vascular involvement in rheumatic diseases: 'vascular rheumatology' Arthritis Res Ther 10 2008 224
4. N. Thairu, S. Kiriakidis, P. Dawson, and E. Paleolog Angiogenesis as a therapeutic target in arthritis in 2011: learning the lessons of the colorectal cancer experience Angiogenesis 14 2011 223 234
5. D.P. Sieveking, R.W. Chow, and M.K. Ng Androgens, angiogenesis and cardiovascular regeneration Curr Opin Endocrinol Diabetes Obes 17 2010 277 283
6. H. Al Sabti Therapeutic angiogenesis in cardiovascular disease J Cardiothorac Surg 2 2007 49
7. S. Goel, D.G. Duda, L. Xu, L.L. Munn, Y. Boucher, and D. Fukumura Normalization of the vasculature for treatment of cancer and other diseases Physiol Rev 91 2011 1071 1121
8. P. Nyberg, L. Xie, and R. Kalluri Endogenous inhibitors of angiogenesis Cancer Res 65 2005 3967 3979 (Pubitemid 40775631)
9. P. Carmeliet, and R.K. Jain Molecular mechanisms and clinical applications of angiogenesis Nature 473 2011 298 307
10. K. Xu, and O. Cleaver Tubulogenesis during blood vessel formation Semin Cell Dev Biol 22 2011 993 1004
11. H.D.Z. Shi Study on chemical components and pharmacological activities of Carya cathayensis Sarg. Chin Tradit Patent Med 31 2009 924 928
12. Y.P.Z.H. Yuan, X.Q. Qin, and X.D. Liu Study on components in the shell of the walnut HeiLongjiang Med J 19 2006 33 34
13. M.Z.Y. Zhan Research progress on chemical compounds and pharmacological action of the Carya tree and its bark J Trop Med 8 2008 87 89
14. T.Z.H. Zhang Research progress on chemical compounds of the green peel of Carya cathayensis Sarg. and its biological activity Food Sci Technol 5 2007 117 119
15. X.D. Cao, Z.S. Ding, F.S. Jiang, X.H. Ding, J.Z. Chen, and S.H. Chen Antitumor constituents from the leaves of Carya cathayensis Nat Prod Res 26 2012 2089 2094
16. Z.P. He, L.J. Pang, L.C. Mao, and J.L. Sun Antioxidant activities in the extracts from Chinese hickory (Carya cathayensis Sarg.) leaves Food Mach 27 2011 45 47
17. H.H. Chen Research on extraction, isolation and oxidation of total flavonoids in leaves of Carya cathayensis Sarg. 2008 Anhui Agricultural University
18. B.H. Jiang, and L.Z. Liu Akt signaling in regulating angiogenesis Curr Cancer Drug Targets 8 2008 19 26
19. G.D. Kim, O.J. Cheong, S.Y. Bae, J. Shin, and S.K. Lee 6″-Debromohamacanthin A, a bis (indole) alkaloid, inhibits angiogenesis by targeting the vegfr2-mediated PI3K/AKT/mTOR signaling pathways Mar Drugs 11 2013 1087 1103
20. N. Lu, Y. Gao, Y. Ling, Y. Chen, Y. Yang, and H.-Y. Gu Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2 Life Sci 82 2008 956 963
21. C.M. Lin, Y.H. Chen, J.R. Ong, H.P. Ma, K.G. Shyu, and K.J. Bai Functional role of wogonin in anti-angiogenesis Am J Chin Med 40 2012 415 427
22. X. Song, J. Yao, F. Wang, M. Zhou, Y. Zhou, and H. Wang Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein Toxicol Appl Pharmacol 271 2013 144 155
23. C.M. Lin, K.G. Shyu, B.W. Wang, H. Chang, Y.H. Chen, and J.H. Chiu Chrysin suppresses il-6-induced angiogenesis via down-regulation of jak1/stat3 and vegf: An in vitro and in ovo approach J Agric Food Chem 58 2010 7082 7087
24. C.M. Lin, H. Chang, S.Y. Li, I.H. Wu, and J.H. Chiu Chrysin inhibits lipopolysaccharide-induced angiogenesis via down-regulation of vegf/vegfr-2 (kdr) and il-6/il-6r pathways Planta Med 72 2006 708 714 (Pubitemid 44073454)
25. B. Fu, J. Xue, Z. Li, X. Shi, B.-H. Jiang, and J. Fang Chrysin inhibits expression of hypoxia-inducible factor-1α through reducing hypoxia-inducible factor-1α stability and inhibiting its protein synthesis Mol Cancer Ther 6 2007 220 226 (Pubitemid 46206685)