-
1
-
-
77950888281
-
Synthesis and preliminary biological evaluation of chrysin derivatives as potential anticancer drugs
-
Zheng, X.; Zhao, F. F.; Liu, Y. M.; Yao, X.; Zheng, Z. T.; Luo, X.; Liao, D. F. Synthesis and preliminary biological evaluation of chrysin derivatives as potential anticancer drugs. Med. Chem. 2010, 6, 6 - 8.
-
(2010)
Med. Chem.
, vol.6
, pp. 6-8
-
-
Zheng, X.1
Zhao, F.F.2
Liu, Y.M.3
Yao, X.4
Zheng, Z.T.5
Luo, X.6
Liao, D.F.7
-
2
-
-
48649095089
-
Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways
-
Ramos, S. Cancer chemoprevention and chemotherapy: dietary polyphenols and signalling pathways Mol. Nutr. Food Res. 2008, 52, 507-526
-
(2008)
Mol. Nutr. Food Res.
, vol.52
, pp. 507-526
-
-
Ramos, S.1
-
3
-
-
33646812944
-
Flavonoids and vitamin e reduce the release of the angiogenic peptide vascular endothelial growth factor from human tumor cells
-
Schindler, R.; Mentlein, R. Flavonoids and vitamin E reduce the release of the angiogenic peptide vascular endothelial growth factor from human tumor cells J. Nutr. 2006, 136, 1477-1482
-
(2006)
J. Nutr.
, vol.136
, pp. 1477-1482
-
-
Schindler, R.1
Mentlein, R.2
-
4
-
-
1842407860
-
Vascular development: Cellular and molecular regulation
-
Beck, L., Jr.; D'Amore, P. A. Vascular development: cellular and molecular regulation FASEB J. 1997, 11, 365-373
-
(1997)
FASEB J.
, vol.11
, pp. 365-373
-
-
Beck Jr., L.1
D'Amore, P.A.2
-
5
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman, J. Angiogenesis in cancer, vascular, rheumatoid and other disease Nat. Med. 1995, 1, 27-31
-
(1995)
Nat. Med.
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
6
-
-
47649112568
-
Additive prognostic value of interleukin-6 at peak phase of dobutamine stress echocardiography in patients with coronary artery disease. A 6-year follow-up study
-
Ikonomidis, I.; Athanassopoulos, G.; Stamatelopoulos, K.; Lekakis, J.; Revela, I.; Venetsanou, K.; Marinou, M.; Monaco, C.; Cokkinos, D. V.; Nihoyannopoulos, P. Additive prognostic value of interleukin-6 at peak phase of dobutamine stress echocardiography in patients with coronary artery disease. A 6-year follow-up study Am. Heart J. 2008, 156, 269-276
-
(2008)
Am. Heart J.
, vol.156
, pp. 269-276
-
-
Ikonomidis, I.1
Athanassopoulos, G.2
Stamatelopoulos, K.3
Lekakis, J.4
Revela, I.5
Venetsanou, K.6
Marinou, M.7
Monaco, C.8
Cokkinos, D.V.9
Nihoyannopoulos, P.10
-
7
-
-
0037591513
-
Prognostic value of serum levels of interleukin 6 and of serum and plasma levels of vascular endothelial growth factor in hormone-refractory metastatic breast cancer patients
-
Bachelot, T.; Ray-Coquard, I.; Menetrier-Caux, C.; Rastkha, M.; Duc, A.; Blay, J. Y. Prognostic value of serum levels of interleukin 6 and of serum and plasma levels of vascular endothelial growth factor in hormone-refractory metastatic breast cancer patients Br. J. Cancer 2003, 88, 1721-1726
-
(2003)
Br. J. Cancer
, vol.88
, pp. 1721-1726
-
-
Bachelot, T.1
Ray-Coquard, I.2
Menetrier-Caux, C.3
Rastkha, M.4
Duc, A.5
Blay, J.Y.6
-
8
-
-
66149092577
-
IL-6 loss causes ventricular dysfunction, fibrosis, reduced capillary density, and dramatically alters the cell populations of the developing and adult heart
-
Banerjee, I.; Fuseler, J. W.; Intwala, A. R.; Baudino, T. A. IL-6 loss causes ventricular dysfunction, fibrosis, reduced capillary density, and dramatically alters the cell populations of the developing and adult heart Am. J. Physiol. Heart Circ. Physiol. 2009, 296, H1694-H1704
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.296
-
-
Banerjee, I.1
Fuseler, J.W.2
Intwala, A.R.3
Baudino, T.A.4
-
9
-
-
17844396959
-
Interleukin-6 induces transcriptional activation of vascular endothelial growth factor (VEGF) in astrocytes in vivo and regulates VEGF promoter activity in glioblastoma cells via direct interaction between STAT3 and Sp1
-
Loeffler, S.; Fayard, B.; Weis, J.; Weissenberger, J. Interleukin-6 induces transcriptional activation of vascular endothelial growth factor (VEGF) in astrocytes in vivo and regulates VEGF promoter activity in glioblastoma cells via direct interaction between STAT3 and Sp1 Int. J. Cancer 2005, 115, 202-213
-
(2005)
Int. J. Cancer
, vol.115
, pp. 202-213
-
-
Loeffler, S.1
Fayard, B.2
Weis, J.3
Weissenberger, J.4
-
10
-
-
0041677606
-
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
-
Heinrich, P. C.; Behrmann, I.; Haan, S.; Hermanns, H. M.; Muller-Newen, G.; Schaper, F. Principles of interleukin (IL)-6-type cytokine signalling and its regulation Biochem. J. 2003, 374, 1-20
-
(2003)
Biochem. J.
, vol.374
, pp. 1-20
-
-
Heinrich, P.C.1
Behrmann, I.2
Haan, S.3
Hermanns, H.M.4
Muller-Newen, G.5
Schaper, F.6
-
11
-
-
58149122747
-
Activated STAT3 is a mediator and biomarker of VEGF endothelial activation
-
Chen, S. H.; Murphy, D. A.; Lassoued, W.; Thurston, G.; Feldman, M. D.; Lee, W. M. Activated STAT3 is a mediator and biomarker of VEGF endothelial activation Cancer Biol. Ther. 2008, 7, 1994-2003
-
(2008)
Cancer Biol. Ther.
, vol.7
, pp. 1994-2003
-
-
Chen, S.H.1
Murphy, D.A.2
Lassoued, W.3
Thurston, G.4
Feldman, M.D.5
Lee, W.M.6
-
12
-
-
0015822275
-
Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
-
Jaffe, E. A.; Nachman, R. L.; Becker, C. G.; Minick, C. R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria J. Clin. Invest. 1973, 52, 2745-2756
-
(1973)
J. Clin. Invest.
, vol.52
, pp. 2745-2756
-
-
Jaffe, E.A.1
Nachman, R.L.2
Becker, C.G.3
Minick, C.R.4
-
13
-
-
0037233190
-
Angiogenesis assays: A critical overview
-
Auerbach, R.; Lewis, R.; Shinners, B.; Kubai, L.; Akhtar, N. Angiogenesis assays: a critical overview Clin. Chem. 2003, 49, 32-40
-
(2003)
Clin. Chem.
, vol.49
, pp. 32-40
-
-
Auerbach, R.1
Lewis, R.2
Shinners, B.3
Kubai, L.4
Akhtar, N.5
-
14
-
-
33748421494
-
Protective role of wogonin against lipopolysaccharide-induced angiogenesis via VEGFR-2, not VEGFR-1
-
Lin, C. M.; Chang, H.; Chen, Y. H.; Li, S. Y.; Wu, I. H.; Chiu, J. H. Protective role of wogonin against lipopolysaccharide-induced angiogenesis via VEGFR-2, not VEGFR-1 Int. Immunopharmacol. 2006, 6, 1690-1698
-
(2006)
Int. Immunopharmacol.
, vol.6
, pp. 1690-1698
-
-
Lin, C.M.1
Chang, H.2
Chen, Y.H.3
Li, S.Y.4
Wu, I.H.5
Chiu, J.H.6
-
15
-
-
23844540283
-
Antiangiogenic activity of nasunin, an antioxidant anthocyanin, in eggplant peels
-
Matsubara, K.; Kaneyuki, T.; Miyake, T.; Mori, M. Antiangiogenic activity of nasunin, an antioxidant anthocyanin, in eggplant peels J. Agric. Food Chem. 2005, 53, 6272-6275
-
(2005)
J. Agric. Food Chem.
, vol.53
, pp. 6272-6275
-
-
Matsubara, K.1
Kaneyuki, T.2
Miyake, T.3
Mori, M.4
-
16
-
-
0142122225
-
Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-α in cultured human umbilical vein endothelial cells
-
Wang, B. W.; Chang, H.; Lin, S.; Kuan, P.; Shyu, K. G. Induction of matrix metalloproteinases-14 and -2 by cyclical mechanical stretch is mediated by tumor necrosis factor-α in cultured human umbilical vein endothelial cells Cardiovasc. Res. 2003, 59, 460-469
-
(2003)
Cardiovasc. Res.
, vol.59
, pp. 460-469
-
-
Wang, B.W.1
Chang, H.2
Lin, S.3
Kuan, P.4
Shyu, K.G.5
-
17
-
-
34447342587
-
Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3 (STAT3) promotes choroidal neovascularization
-
Izumi-Nagai, K.; Nagai, N.; Ozawa, Y.; Mihara, M.; Ohsugi, Y.; Kurihara, T.; Koto, T.; Satofuka, S.; Inoue, M.; Tsubota, K.; Okano, H.; Oike, Y.; Ishida, S. Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3 (STAT3) promotes choroidal neovascularization Am. J. Pathol. 2007, 170, 2149-2158
-
(2007)
Am. J. Pathol.
, vol.170
, pp. 2149-2158
-
-
Izumi-Nagai, K.1
Nagai, N.2
Ozawa, Y.3
Mihara, M.4
Ohsugi, Y.5
Kurihara, T.6
Koto, T.7
Satofuka, S.8
Inoue, M.9
Tsubota, K.10
Okano, H.11
Oike, Y.12
Ishida, S.13
-
18
-
-
23944519382
-
Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulation
-
Yang, S. H.; Lin, J. K.; Huang, C. J.; Chen, W. S.; Li, S. Y.; Chiu, J. H. Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulation J. Surg. Res. 2005, 128, 140-146
-
(2005)
J. Surg. Res.
, vol.128
, pp. 140-146
-
-
Yang, S.H.1
Lin, J.K.2
Huang, C.J.3
Chen, W.S.4
Li, S.Y.5
Chiu, J.H.6
-
19
-
-
67649086164
-
Correlation between antiangiogenic activity and antioxidant activity of various components from propolis
-
Ahn, M. R.; Kunimasa, K.; Kumazawa, S.; Nakayama, T.; Kaji, K.; Uto, Y.; Hori, H.; Nagasawa, H.; Ohta, T. Correlation between antiangiogenic activity and antioxidant activity of various components from propolis Mol. Nutr. Food Res. 2009, 53, 643-651
-
(2009)
Mol. Nutr. Food Res.
, vol.53
, pp. 643-651
-
-
Ahn, M.R.1
Kunimasa, K.2
Kumazawa, S.3
Nakayama, T.4
Kaji, K.5
Uto, Y.6
Hori, H.7
Nagasawa, H.8
Ohta, T.9
-
20
-
-
33746075933
-
Chrysin inhibits lipopolysaccharide-induced angiogenesis via down-regulation of VEGF/VEGFR-2(KDR) and IL-6/IL-6R pathways
-
Lin, C. M.; Chang, H.; Li, S. Y.; Wu, I. H.; Chiu, J. H. Chrysin inhibits lipopolysaccharide-induced angiogenesis via down-regulation of VEGF/VEGFR-2(KDR) and IL-6/IL-6R pathways Planta Med. 2006, 72, 708-714
-
(2006)
Planta Med.
, vol.72
, pp. 708-714
-
-
Lin, C.M.1
Chang, H.2
Li, S.Y.3
Wu, I.H.4
Chiu, J.H.5
-
21
-
-
62549142650
-
Bacterial endotxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling
-
Leung, K. W.; Barnstable, C. J.; Tombran-Tink, J. Bacterial endotxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling Mol. Immunol. 2009, 46, 1374-1386
-
(2009)
Mol. Immunol.
, vol.46
, pp. 1374-1386
-
-
Leung, K.W.1
Barnstable, C.J.2
Tombran-Tink, J.3
-
22
-
-
33846842258
-
Chrysin inhibits expression of hypoxia-inducible factor-1α through reducing hypoxia-inducible factor-1α stability and inhibiting its protein synthesis
-
Fu, B.; Xue, J.; Li, Z.; Shi, X.; Jiang, B. H.; Fang, J. Chrysin inhibits expression of hypoxia-inducible factor-1α through reducing hypoxia-inducible factor-1α stability and inhibiting its protein synthesis Mol. Cancer Ther. 2007, 6, 220-226
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 220-226
-
-
Fu, B.1
Xue, J.2
Li, Z.3
Shi, X.4
Jiang, B.H.5
Fang, J.6
-
23
-
-
48149083967
-
Effect of flavonoids on rat splenocytes, a structure-activity relationship study
-
López-Posadas, R.; Ballester, I.; Abadía-Molina, A. C.; Suárez, M. D.; Zarzuelo, A.; Martínez-Augustin, O.; Sánchez de Medina, F. Effect of flavonoids on rat splenocytes, a structure-activity relationship study Biochem. Pharmacol. 2008, 76, 495-506
-
(2008)
Biochem. Pharmacol.
, vol.76
, pp. 495-506
-
-
López-Posadas, R.1
Ballester, I.2
Abadía-Molina, A.C.3
Suárez, M.D.4
Zarzuelo, A.5
Martínez-Augustin, O.6
Sánchez De Medina, F.7
-
24
-
-
59649121769
-
Synthesis and promotion angiogenesis effect of chrysin derivatives coupled to NO donors
-
Peng, S. M.; Zou, X. Q.; Ding, H. L.; Ding, Y. L.; Lin, Y. B. Synthesis and promotion angiogenesis effect of chrysin derivatives coupled to NO donors Bioorg. Med. Chem. Lett. 2009, 19, 1264-1266
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 1264-1266
-
-
Peng, S.M.1
Zou, X.Q.2
Ding, H.L.3
Ding, Y.L.4
Lin, Y.B.5
-
25
-
-
53049106036
-
Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model
-
Raina, K.; Rajamanickam, S.; Singh, R. P.; Deep, G.; Chittezhath, M.; Agarwal, R. Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model Cancer Res. 2008, 68, 6822-6830
-
(2008)
Cancer Res.
, vol.68
, pp. 6822-6830
-
-
Raina, K.1
Rajamanickam, S.2
Singh, R.P.3
Deep, G.4
Chittezhath, M.5
Agarwal, R.6
-
26
-
-
66149179267
-
Comparison of flavonoids and isoflavonoids as antioxidants
-
Raina, K.; Rajamanickam, S.; Singh, R. P.; Deep, G.; Chittezhath, M.; Agarwal, R. Comparison of flavonoids and isoflavonoids as antioxidants J. Agric. Food Chem. 2009, 57, 3780-3785
-
(2009)
J. Agric. Food Chem.
, vol.57
, pp. 3780-3785
-
-
Raina, K.1
Rajamanickam, S.2
Singh, R.P.3
Deep, G.4
Chittezhath, M.5
Agarwal, R.6
-
27
-
-
55249091877
-
Protective effects of genistein on proinflammatory pathways in human brain microvascular endothelial cells
-
Lee, Y. W.; Lee, W. H. Protective effects of genistein on proinflammatory pathways in human brain microvascular endothelial cells J. Nutr. Biochem. 2008, 19, 819-825
-
(2008)
J. Nutr. Biochem.
, vol.19
, pp. 819-825
-
-
Lee, Y.W.1
Lee, W.H.2
-
28
-
-
62649118631
-
Chrysin, a natural flavone, improves murine inflammatory bowel diseases
-
Shin, E. K.; Kwon, H. S.; Kim, Y. H.; Shin, H. K.; Kim, J. K. Chrysin, a natural flavone, improves murine inflammatory bowel diseases Biochem. Biophys. Res. Commun. 2009, 381, 502-507
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.381
, pp. 502-507
-
-
Shin, E.K.1
Kwon, H.S.2
Kim, Y.H.3
Shin, H.K.4
Kim, J.K.5
-
29
-
-
12744268595
-
Chrysin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression through the inhibition of nuclear factor for IL-6 (NF-IL6) DNA-binding activity
-
Woo, K. J.; Jeong, Y. J.; Inoue, H.; Park, J. W.; Kwon, T. K. Chrysin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression through the inhibition of nuclear factor for IL-6 (NF-IL6) DNA-binding activity FEBS Lett. 2005, 579, 705-711
-
(2005)
FEBS Lett.
, vol.579
, pp. 705-711
-
-
Woo, K.J.1
Jeong, Y.J.2
Inoue, H.3
Park, J.W.4
Kwon, T.K.5
-
30
-
-
52949136974
-
Ups and downs: The STAT1:STAT3 seesaw of interferon and gp130 receptor signalling
-
Regis, G.; Pensa, S.; Boselli, D.; Novelli, F.; Poli, V. Ups and downs: the STAT1:STAT3 seesaw of interferon and gp130 receptor signalling Semin. Cell Dev. Biol. 2008, 19, 351-359
-
(2008)
Semin. Cell Dev. Biol.
, vol.19
, pp. 351-359
-
-
Regis, G.1
Pensa, S.2
Boselli, D.3
Novelli, F.4
Poli, V.5
-
31
-
-
0141960055
-
Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation
-
Yahata, Y.; Shirakata, Y.; Tokumaru, S.; Yamasaki, K.; Sayama, K.; Hanakawa, Y.; Detmar, M.; Hashimoto, K. Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation J. Biol. Chem. 2003, 278, 40026-40031
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 40026-40031
-
-
Yahata, Y.1
Shirakata, Y.2
Tokumaru, S.3
Yamasaki, K.4
Sayama, K.5
Hanakawa, Y.6
Detmar, M.7
Hashimoto, K.8
-
32
-
-
44449128168
-
Dietary flavonoids differentially reduce oxidized LDL-induced apoptosis in human endothelial cells: Role of MAPK- and JAK/STAT-signaling
-
Choi, J. S.; Choi, Y. J.; Shin, S. Y.; Li, J.; Kang, S. W.; Bae, J. Y.; Kim, D. S.; Ji, G. E.; Kang, J. S.; Kang, Y. H. Dietary flavonoids differentially reduce oxidized LDL-induced apoptosis in human endothelial cells: role of MAPK- and JAK/STAT-signaling J. Nutr. 2008, 138, 983-990
-
(2008)
J. Nutr.
, vol.138
, pp. 983-990
-
-
Choi, J.S.1
Choi, Y.J.2
Shin, S.Y.3
Li, J.4
Kang, S.W.5
Bae, J.Y.6
Kim, D.S.7
Ji, G.E.8
Kang, J.S.9
Kang, Y.H.10
-
33
-
-
34547975508
-
Signal transducers and activators of transcription 3 up-regulates vascular endothelial growth factor production and tumor angiogenesis in head and neck squamous cell carcinoma
-
Masuda, M.; Ruan, H. Y.; Ito, A.; Nakashima, T.; Toh, S.; Wakasaki, T.; Yasumatsu, R.; Kutratomi, Y.; Komune, S.; Weinstein, I. B. Signal transducers and activators of transcription 3 up-regulates vascular endothelial growth factor production and tumor angiogenesis in head and neck squamous cell carcinoma Oral Oncol. 2007, 43, 785-790.
-
(2007)
Oral Oncol.
, vol.43
, pp. 785-790
-
-
Masuda, M.1
Ruan, H.Y.2
Ito, A.3
Nakashima, T.4
Toh, S.5
Wakasaki, T.6
Yasumatsu, R.7
Kutratomi, Y.8
Komune, S.9
Weinstein, I.B.10
-
34
-
-
62349117597
-
Growth inhibition and regression of lung tumors by silibinin: Modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-κB and signal transducers and activators of transcription 3
-
Tyagi, A.; Singh, R. P.; Ramasamy, K.; Raina, K.; Redente, E. F.; Dwyer-Nield, L. D.; Radcliffe, R. A.; Malkinson, A. M.; Agarwal, R. Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-κB and signal transducers and activators of transcription 3 Cancer Prev. Res. (Phila. Pa.) 2009, 2, 74-83.
-
(2009)
Cancer Prev. Res. (Phila. Pa.)
, vol.2
, pp. 74-83
-
-
Tyagi, A.1
Singh, R.P.2
Ramasamy, K.3
Raina, K.4
Redente, E.F.5
Dwyer-Nield, L.D.6
Radcliffe, R.A.7
Malkinson, A.M.8
Agarwal, R.9
-
35
-
-
61449206288
-
Radiation-induced HIF-1α cell survival pathway is inhibited by soy isoflavones in prostate cancer cells
-
Singh-Gupta, V.; Zhang, H.; Banerjee, S.; Kong, D.; Raffoul, J. J.; Sarkar, F. H.; Hillman, G. G. Radiation-induced HIF-1α cell survival pathway is inhibited by soy isoflavones in prostate cancer cells Int. J. Cancer 2009, 124, 1675-1684.
-
(2009)
Int. J. Cancer
, vol.124
, pp. 1675-1684
-
-
Singh-Gupta, V.1
Zhang, H.2
Banerjee, S.3
Kong, D.4
Raffoul, J.J.5
Sarkar, F.H.6
Hillman, G.G.7
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