-
1
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B, Kinzler KW (2004) Cancer genes and the pathways they control. Nat Med 10: 789-99.
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
3
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, et al. (2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350: 2129-39.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
-
4
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Jänne PA, Lee JC, Tracy S, Greulich H, et al. (2004) EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304: 1497-500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
-
5
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, Doherty J, Politi K, et al. (2004) EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 101: 13306-11.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
-
6
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, Riely GJ, Somwar R, et al. (2005) Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2: e73.
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
Riely, G.J.4
Somwar, R.5
-
7
-
-
24944497744
-
Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
-
Eberhard DA, Johnson BE, Amler LC, Goddard AD, Heldens SL, et al. (2005) Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 23: 5900-9.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5900-5909
-
-
Eberhard, D.A.1
Johnson, B.E.2
Amler, L.C.3
Goddard, A.D.4
Heldens, S.L.5
-
8
-
-
33646228635
-
KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
-
Lièvre A, Bachet J, Le Corre D, Boige V, Landi B, et al. (2006) KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res 66: 3992-5.
-
(2006)
Cancer Res
, vol.66
, pp. 3992-3995
-
-
Lièvre, A.1
Bachet, J.2
Le Corre, D.3
Boige, V.4
Landi, B.5
-
9
-
-
38649099966
-
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab
-
Lièvre A, Bachet J, Boige V, Cayre A, Le Corre D, et al. (2008) KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. J Clin Oncol 26: 374-9.
-
(2008)
J Clin Oncol
, vol.26
, pp. 374-379
-
-
Lièvre, A.1
Bachet, J.2
Boige, V.3
Cayre, A.4
Le Corre, D.5
-
10
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M, Van Cutsem E, Siena S, et al. (2008) Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 26: 1626-34.
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
Van Cutsem, E.4
Siena, S.5
-
11
-
-
2342472111
-
PAP: Detection of ultra rare mutations depends on P* oligonucleotides: "sleeping beauties" awakened by the kiss of pyrophosphorolysis
-
Liu Q, Sommer SS (2004) PAP: detection of ultra rare mutations depends on P* oligonucleotides: "sleeping beauties" awakened by the kiss of pyrophosphorolysis. Hum Mutat 23: 426-36.
-
(2004)
Hum Mutat
, vol.23
, pp. 426-436
-
-
Liu, Q.1
Sommer, S.S.2
-
12
-
-
0036515416
-
Emerging molecular markers of cancer
-
Sidransky D (2002) Emerging molecular markers of cancer. Nat Rev Cancer 2: 210-9.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 210-219
-
-
Sidransky, D.1
-
13
-
-
28044468634
-
Detection and quantification of mutations in the plasma of patients with colorectal tumors
-
Diehl F, Li M, Dressman D, He Y, Shen D, et al. (2005) Detection and quantification of mutations in the plasma of patients with colorectal tumors. Proc Natl Acad Sci U S A 102: 16368-73.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 16368-16373
-
-
Diehl, F.1
Li, M.2
Dressman, D.3
He, Y.4
Shen, D.5
-
14
-
-
0029124197
-
Allele-specific competitive blocker PCR: A one-step method with applicability to pool screening
-
Orou A, Fechner B, Utermann G, Menzel HJ (1995) Allele-specific competitive blocker PCR: a one-step method with applicability to pool screening. Hum Mutat 6: 163-9.
-
(1995)
Hum Mutat
, vol.6
, pp. 163-169
-
-
Orou, A.1
Fechner, B.2
Utermann, G.3
Menzel, H.J.4
-
15
-
-
0026525693
-
A novel blocker-PCR method for detection of rare mutant alleles in the presence of an excess amount of normal DNA
-
Seyama T, Ito T, Hayashi T, Mizuno T, Nakamura N, et al. (1992) A novel blocker-PCR method for detection of rare mutant alleles in the presence of an excess amount of normal DNA. Nucleic Acids Res 20: 2493-6.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 2493-2496
-
-
Seyama, T.1
Ito, T.2
Hayashi, T.3
Mizuno, T.4
Nakamura, N.5
-
16
-
-
0036177726
-
Diagnostic biochip array for fast and sensitive detection of K-ras mutations in stool
-
Prix L, Uciechowski P, Böckmann B, Giesing M, Schuetz AJ (2002) Diagnostic biochip array for fast and sensitive detection of K-ras mutations in stool. Clin Chem 48: 428-35.
-
(2002)
Clin Chem
, vol.48
, pp. 428-435
-
-
Prix, L.1
Uciechowski, P.2
Böckmann, B.3
Giesing, M.4
Schuetz, A.J.5
-
17
-
-
0345356408
-
Real-time genotyping with oligonucleotide probes containing locked nucleic acids
-
Ugozzoli LA, Latorra D, Puckett R, Pucket R, Arar K, et al. (2004) Real-time genotyping with oligonucleotide probes containing locked nucleic acids. Anal Biochem 324: 143-52.
-
(2004)
Anal Biochem
, vol.324
, pp. 143-152
-
-
Ugozzoli, L.A.1
Latorra, D.2
Puckett, R.3
Pucket, R.4
Arar, K.5
-
18
-
-
0038723184
-
Enhanced allele-specific PCR discrimination in SNP genotyping using 3′ locked nucleic acid (LNA) primers
-
Latorra D, Campbell K, Wolter A, Hurley JM (2003) Enhanced allele-specific PCR discrimination in SNP genotyping using 3′ locked nucleic acid (LNA) primers. Hum Mutat 22: 79-85.
-
(2003)
Hum Mutat
, vol.22
, pp. 79-85
-
-
Latorra, D.1
Campbell, K.2
Wolter, A.3
Hurley, J.M.4
-
19
-
-
0034094854
-
Determining SNP allele frequencies in DNA pools
-
Breen G, Harold D, Ralston S, Shaw D, St Clair D (2000) Determining SNP allele frequencies in DNA pools. Biotechniques 28: 464-6, 468470.
-
(2000)
Biotechniques
, vol.28
, Issue.464-466
, pp. 468470
-
-
Breen, G.1
Harold, D.2
Ralston, S.3
Shaw, D.4
St Clair, D.5
-
20
-
-
0034090681
-
High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR
-
Germer S, Holland MJ, Higuchi R (2000) High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR. Genome Res 10: 258-66.
-
(2000)
Genome Res
, vol.10
, pp. 258-266
-
-
Germer, S.1
Holland, M.J.2
Higuchi, R.3
-
21
-
-
0024605518
-
Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)
-
Newton CR, Graham A, Heptinstall LE, Powell SJ, Summers C, et al. (1989) Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res 17: 2503-16.
-
(1989)
Nucleic Acids Res
, vol.17
, pp. 2503-2516
-
-
Newton, C.R.1
Graham, A.2
Heptinstall, L.E.3
Powell, S.J.4
Summers, C.5
-
23
-
-
36148998827
-
FLAG assay as a novel method for real-time signal generation during PCR: Application to detection and genotyping of KRAS codon 12 mutations
-
Amicarelli G, Shehi E, Makrigiorgos GM, Adlerstein D (2007) FLAG assay as a novel method for real-time signal generation during PCR: application to detection and genotyping of KRAS codon 12 mutations. Nucleic Acids Res 35: e131.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Amicarelli, G.1
Shehi, E.2
Makrigiorgos, G.M.3
Adlerstein, D.4
-
24
-
-
1542469713
-
Measurement of gene expression in archival paraffin-embedded tissues: Development and performance of a 92-gene reverse transcriptase-polymerase chain reaction assay
-
Cronin M, Pho M, Dutta D, Stephans JC, Shak S, et al. (2004) Measurement of gene expression in archival paraffin-embedded tissues: development and performance of a 92-gene reverse transcriptase-polymerase chain reaction assay. Am J Pathol 164: 35-42.
-
(2004)
Am J Pathol
, vol.164
, pp. 35-42
-
-
Cronin, M.1
Pho, M.2
Dutta, D.3
Stephans, J.C.4
Shak, S.5
-
25
-
-
0002713231
-
Allele-specific enzymatic amplification of beta-globin genomic DNA for diagnosis of sickle cell anemia
-
doi:2704745
-
Wu DY, Ugozzoli L, Pal BK, Wallace RB (1989) Allele-specific enzymatic amplification of beta-globin genomic DNA for diagnosis of sickle cell anemia. Proc Natl Acad Sci U S A 86: 2757-60. doi:2704745.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 2757-2760
-
-
Wu, D.Y.1
Ugozzoli, L.2
Pal, B.K.3
Wallace, R.B.4
-
26
-
-
0026698636
-
Extension of base mispairs by Taq DNA polymerase: Implications for single nucleotide discrimination in PCR
-
doi:1408758
-
Huang MM, Arnheim N, Goodman MF (1992) Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR. Nucleic Acids Res 20: 4567-73. doi:1408758.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 4567-4573
-
-
Huang, M.M.1
Arnheim, N.2
Goodman, M.F.3
-
27
-
-
0025305576
-
Effects of primer-template mismatches on the polymerase chain reaction: Human immunodeficiency virus type 1 model studies
-
doi:2179874
-
Kwok S, Kellogg DE, McKinney N, Spasic D, Goda L, et al. (1990) Effects of primer-template mismatches on the polymerase chain reaction: human immunodeficiency virus type 1 model studies. Nucleic Acids Res 18: 999-1005. doi:2179874.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 999-1005
-
-
Kwok, S.1
Kellogg, D.E.2
McKinney, N.3
Spasic, D.4
Goda, L.5
-
28
-
-
0033739215
-
Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: A population-based study
-
Samowitz WS, Curtin K, Schaffer D, Robertson M, Leppert M, et al. (2000) Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study. Cancer Epidemiol Biomarkers Prev 9: 1193-7.
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 1193-1197
-
-
Samowitz, W.S.1
Curtin, K.2
Schaffer, D.3
Robertson, M.4
Leppert, M.5
-
29
-
-
0032490124
-
Kirsten ras mutations in patients with colorectal cancer: The multicenter "RASCAL" study
-
doi:9586664
-
Andreyev HJ, Norman AR, Cunningham D, Oates JR, Clarke PA (1998) Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study. J Natl Cancer Inst 90: 675-84. doi:9586664.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 675-684
-
-
Andreyev, H.J.1
Norman, A.R.2
Cunningham, D.3
Oates, J.R.4
Clarke, P.A.5
-
30
-
-
0001155699
-
-
New York: Greene Publishing Associates and John Wiley&Sons. pp, to
-
Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman J, et al. (1992) Short Protocols in Molecular Biology. Second. New York: Greene Publishing Associates and John Wiley&Sons. pp 8-10 to 8-12.
-
(1992)
Short Protocols in Molecular Biology. Second
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.5
-
31
-
-
0030977113
-
Quantitation of target molecules from polymerase chain reaction-based limiting dilution assays
-
doi:9171217
-
Rodrigo AG, Goracke PC, Rowhanian K, Mullins JI (1997) Quantitation of target molecules from polymerase chain reaction-based limiting dilution assays. AIDS Res Hum Retroviruses 13: 737-42. doi:9171217.
-
(1997)
AIDS Res Hum Retroviruses
, vol.13
, pp. 737-742
-
-
Rodrigo, A.G.1
Goracke, P.C.2
Rowhanian, K.3
Mullins, J.I.4
-
32
-
-
19944422061
-
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer
-
doi:NEJMoa041588
-
Paik S, Shak S, Tang G, Kim C, Baker J, et al. (2004) A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 351: 2817-26. doi:NEJMoa041588.
-
(2004)
N Engl J Med
, vol.351
, pp. 2817-2826
-
-
Paik, S.1
Shak, S.2
Tang, G.3
Kim, C.4
Baker, J.5
-
33
-
-
16644393662
-
-
Parsons BL, McKinzie PB, Heflich RH (2005) Allele-specific competitive blocker-PCR detection of rare base substitution. Methods Mol Biol 291: 235-45. doi:1-59259-840-4:235.
-
Parsons BL, McKinzie PB, Heflich RH (2005) Allele-specific competitive blocker-PCR detection of rare base substitution. Methods Mol Biol 291: 235-45. doi:1-59259-840-4:235.
-
-
-
-
34
-
-
3242882243
-
Peptide nucleic acid clamp PCR: A novel K-ras mutation detection assay for colorectal cancer micrometastases in lymph nodes
-
doi:15221969
-
Taback B, Bilchik AJ, Saha S, Nakayama T, Wiese DA, et al. (2004) Peptide nucleic acid clamp PCR: a novel K-ras mutation detection assay for colorectal cancer micrometastases in lymph nodes. Int J Cancer 111: 409-14. doi:15221969.
-
(2004)
Int J Cancer
, vol.111
, pp. 409-414
-
-
Taback, B.1
Bilchik, A.J.2
Saha, S.3
Nakayama, T.4
Wiese, D.A.5
-
35
-
-
0023088933
-
Dissociation kinetics of 19 base paired oligonucleotide-DNA duplexes containing different single mismatched base pairs
-
doi:3822815
-
Ikuta S, Takagi K, Wallace RB, Itakura K (1987) Dissociation kinetics of 19 base paired oligonucleotide-DNA duplexes containing different single mismatched base pairs. Nucleic Acids Res 15: 797-811. doi:3822815.
-
(1987)
Nucleic Acids Res
, vol.15
, pp. 797-811
-
-
Ikuta, S.1
Takagi, K.2
Wallace, R.B.3
Itakura, K.4
-
36
-
-
33744814477
-
Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer
-
doi:JCO.2005.04.7985
-
Paik S, Tang G, Shak S, Kim C, Baker J, et al. (2006) Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer. J Clin Oncol 24: 3726-34. doi:JCO.2005.04.7985.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3726-3734
-
-
Paik, S.1
Tang, G.2
Shak, S.3
Kim, C.4
Baker, J.5
-
37
-
-
14644418434
-
-
Akbari M, Hansen MD, Halgunset J, Skorpen F, Krokan HE (2005) Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner. The Journal of Molecular Diagnostics: JMD 7: 36-9. doi:7/1/36.
-
Akbari M, Hansen MD, Halgunset J, Skorpen F, Krokan HE (2005) Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner. The Journal of Molecular Diagnostics: JMD 7: 36-9. doi:7/1/36.
-
-
-
-
38
-
-
0032755991
-
A high frequency of sequence alterations is due to formalin fixation of archival specimens
-
doi:10550302
-
Williams C, Pontén F, Moberg C, Söderkvist P, Uhlén M, et al. (1999) A high frequency of sequence alterations is due to formalin fixation of archival specimens. Am J Pathol 155: 1467-71. doi:10550302.
-
(1999)
Am J Pathol
, vol.155
, pp. 1467-1471
-
-
Williams, C.1
Pontén, F.2
Moberg, C.3
Söderkvist, P.4
Uhlén, M.5
-
39
-
-
32044467562
-
Assessing EGFR mutations
-
author reply 526-8. doi:354/5/526
-
Marchetti A, Felicioni L, Buttitta F (2006) Assessing EGFR mutations. N Engl J Med 354: 526-8; author reply 526-8. doi:354/5/526.
-
(2006)
N Engl J Med
, vol.354
, pp. 526-528
-
-
Marchetti, A.1
Felicioni, L.2
Buttitta, F.3
-
40
-
-
0037119584
-
Allelic variation in human gene expression
-
doi:12183620
-
Yan H, Yuan W, Velculescu VE, Vogelstein B, Kinzler KW (2002) Allelic variation in human gene expression. Science 297: 1143. doi:12183620.
-
(2002)
Science
, vol.297
, pp. 1143
-
-
Yan, H.1
Yuan, W.2
Velculescu, V.E.3
Vogelstein, B.4
Kinzler, K.W.5
-
41
-
-
0012789869
-
Allelic Variation in Gene Expression Is Common in the Human Genome
-
doi:10.1101/gr.1006603
-
Lo HS, Wang Z, Hu Y, Yang HH, Gere S, et al. (2003) Allelic Variation in Gene Expression Is Common in the Human Genome. Genome Res 13: 1855-1862. doi:10.1101/gr.1006603.
-
(2003)
Genome Res
, vol.13
, pp. 1855-1862
-
-
Lo, H.S.1
Wang, Z.2
Hu, Y.3
Yang, H.H.4
Gere, S.5
-
42
-
-
40149090710
-
-
Serre D, Gurd S, Ge B, Sladek R, Sinnett D, et al. (2008) Differential allelic expression in the human genome: a robust approach to identify genetic and epigenetic cis-acting mechanisms regulating gene expression. PLoS Genet 4: e1000006.
-
Serre D, Gurd S, Ge B, Sladek R, Sinnett D, et al. (2008) Differential allelic expression in the human genome: a robust approach to identify genetic and epigenetic cis-acting mechanisms regulating gene expression. PLoS Genet 4: e1000006.
-
-
-
-
43
-
-
0034744742
-
ARMS allele-specific amplification-based detection of mutant p53 DNA and mRNA in tumors of the breast
-
Hodgson DR, Clayton SJ, Girdler F, Brotherick I, Shenton B, et al. (2001) ARMS allele-specific amplification-based detection of mutant p53 DNA and mRNA in tumors of the breast. Clin Chem 47: 774-8.
-
(2001)
Clin Chem
, vol.47
, pp. 774-778
-
-
Hodgson, D.R.1
Clayton, S.J.2
Girdler, F.3
Brotherick, I.4
Shenton, B.5
-
44
-
-
57849115557
-
Evaluation of tumor gene expression and K-Ras mutations in FFPE tumor tissue as predictors of response to cetuximab in metastatic colorectal cancer
-
Abstr 3512
-
Baker JB, Dutta D, Watson D, Maddala T, Shak S, et al. (2008) Evaluation of tumor gene expression and K-Ras mutations in FFPE tumor tissue as predictors of response to cetuximab in metastatic colorectal cancer. J Clin Oncol 26: Abstr 3512.
-
(2008)
J Clin Oncol
, vol.26
-
-
Baker, J.B.1
Dutta, D.2
Watson, D.3
Maddala, T.4
Shak, S.5
|