FLAG assay as a novel method for real-time signal generation during PCR: Application to detection and genotyping of KRAS codon 12 mutations

Nucleic Acids Research

Volumn 35, Issue 19, 2007, Pages

  Amicarelli, Giulia ^a   Shehi, Erlet ^a   Makrigiorgos, Mike G ^b   Adlerstein, Daniel ^a  

^a Diasorin SpA   (Italy)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENDONUCLEASE; ONCOPROTEIN; PROTEIN KRAS; UNCLASSIFIED DRUG; KRAS PROTEIN, HUMAN; PEPTIDE NUCLEIC ACID; RAS PROTEIN;

AMPLICON; ARTICLE; CODON; CONTROLLED STUDY; DNA SEQUENCE; GENE AMPLIFICATION; GENE MUTATION; GENETIC SCREENING; GENOTYPE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HUMAN TISSUE; MUTANT; NUCLEIC ACID PROBE; ONCOGENE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; THERMOSTABILITY; WILD TYPE; CELL LINE; COLORECTAL TUMOR; GENETICS; METHODOLOGY; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; ONCOGENE RAS; POLYMERASE CHAIN REACTION; TIME; VALIDATION STUDY;

CELL LINE; CODON; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; GENES, RAS; GENOTYPE; HUMANS; OLIGONUCLEOTIDE PROBES; PEPTIDE NUCLEIC ACIDS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; TIME FACTORS;

EID: 36148998827     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm809     Document Type: Article

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