PAP: Detection of Ultra Rare Mutations Depends on P* Oligonucleotides: "Sleeping Beauties" Awakened by the Kiss of Pyrophosphorolysis

Human Mutation

Volumn 23, Issue 5, 2004, Pages 426-436

  Liu, Qiang ^a   Sommer, Steve S ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Amplification; Mutation detection; Mutation load; PAP; Pyrophosphorolysis; Rare allele; Somatic mutation

Indexed keywords

BACTERIOPHAGE DNA; GENOMIC DNA; OLIGONUCLEOTIDE;

ALLELE; ANALYTICAL ERROR; BASE MISPAIRING; CLONAL VARIATION; DNA FLANKING REGION; DNA MICROARRAY; GENE AMPLIFICATION; GENE FREQUENCY; GENE IDENTIFICATION; GENE LOCATION; GENETIC SCREENING; GENETIC VARIABILITY; HUMAN; MOLECULAR MODEL; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; POLYMERIZATION; PRIORITY JOURNAL; PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION; REVIEW; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; TECHNIQUE; TRANSGENE; TRANSGENIC MOUSE; WILD TYPE;

ALLELES; ANIMALS; BASE SEQUENCE; DIPHOSPHATES; DNA MUTATIONAL ANALYSIS; DNA-DIRECTED DNA POLYMERASE; HUMANS; MICE; NUCLEIC ACID AMPLIFICATION TECHNIQUES; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDES; POLYMERASE CHAIN REACTION;

MUS MUSCULUS;

EID: 2342472111     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/humu.20036     Document Type: Review

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