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Volumn 4, Issue 2, 2009, Pages

Targeted inactivation of p12Cdk2ap1, CDK2 associating protein 1, leads to early embryonic lethality

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 2 ASSOCIATING PROTEIN 1; UNCLASSIFIED DRUG;

EID: 84887212444     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004518     Document Type: Article
Times cited : (17)

References (45)
  • 1
    • 0028864747 scopus 로고
    • Deleted in oral cancer-1 (doc-1), a novel oral tumor suppressor gene
    • Todd R, McBride J, Tsuji T, Donoff RB, Nagai M, et al. (1995) Deleted in oral cancer-1 (doc-1), a novel oral tumor suppressor gene. Faseb J 9: 1362-1370.
    • (1995) Faseb J , vol.9 , pp. 1362-1370
    • Todd, R.1    McBride, J.2    Tsuji, T.3    Donoff, R.B.4    Nagai, M.5
  • 2
    • 15544391299 scopus 로고    scopus 로고
    • Cloning, mapping, expression, function, and mutation analyses of the human ortholog of the hamster putative tumor suppressor gene Doc-1
    • Tsuji T, Duh FM, Latif F, Popescu NC, Zimonjic DB, et al. (1998) Cloning, mapping, expression, function, and mutation analyses of the human ortholog of the hamster putative tumor suppressor gene Doc-1. J Biol Chem 273: 6704-6709.
    • (1998) J Biol Chem , vol.273 , pp. 6704-6709
    • Tsuji, T.1    Duh, F.M.2    Latif, F.3    Popescu, N.C.4    Zimonjic, D.B.5
  • 3
    • 0034741140 scopus 로고    scopus 로고
    • Reduction of p12DOC-1 expression is a negative prognostic indicator in patients with surgically resected oral squamous cell carcinoma
    • Shintani S, Mihara M, Terakado N, Nakahara Y, Matsumura T, et al. (2001) Reduction of p12DOC-1 expression is a negative prognostic indicator in patients with surgically resected oral squamous cell carcinoma. Clin Cancer Res 7: 2776-2782.
    • (2001) Clin Cancer Res , vol.7 , pp. 2776-2782
    • Shintani, S.1    Mihara, M.2    Terakado, N.3    Nakahara, Y.4    Matsumura, T.5
  • 5
    • 13244266955 scopus 로고    scopus 로고
    • p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin
    • Kim Y, McBride J, Zhang R, Zhou X, Wong DT (2005) p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin. Oncogene 24: 407-418.
    • (2005) Oncogene , vol.24 , pp. 407-418
    • Kim, Y.1    McBride, J.2    Zhang, R.3    Zhou, X.4    Wong, D.T.5
  • 6
    • 17544382992 scopus 로고    scopus 로고
    • p12(DOC-1), a growth suppressor, associates with DNA polymerase alpha/ primase
    • Matsuo K, Shintani S, Tsuji T, Nagata E, Lerman M, et al. (2000) p12(DOC-1), a growth suppressor, associates with DNA polymerase alpha/ primase. Faseb J 14: 1318-1324.
    • (2000) Faseb J , vol.14 , pp. 1318-1324
    • Matsuo, K.1    Shintani, S.2    Tsuji, T.3    Nagata, E.4    Lerman, M.5
  • 7
    • 0036230873 scopus 로고    scopus 로고
    • Apoptosis, proliferation and p12(doc-1) profiles in normal, dysplastic and malignant squamous epithelium of the Syrian hamster cheek pouch model
    • Kohno Y, Patel V, Kim Y, Tsuji T, Chin BR, et al. (2002) Apoptosis, proliferation and p12(doc-1) profiles in normal, dysplastic and malignant squamous epithelium of the Syrian hamster cheek pouch model. Oral Oncol 38: 274-280.
    • (2002) Oral Oncol , vol.38 , pp. 274-280
    • Kohno, Y.1    Patel, V.2    Kim, Y.3    Tsuji, T.4    Chin, B.R.5
  • 8
    • 0033845707 scopus 로고    scopus 로고
    • p12(DOC-1) is a novel cyclin-dependent kinase 2-associated protein
    • Shintani S, Ohyama H, Zhang X, McBride J, Matsuo K, et al. (2000) p12(DOC-1) is a novel cyclin-dependent kinase 2-associated protein. Mol Cell Biol 20: 6300-6307.
    • (2000) Mol Cell Biol , vol.20 , pp. 6300-6307
    • Shintani, S.1    Ohyama, H.2    Zhang, X.3    McBride, J.4    Matsuo, K.5
  • 9
    • 1642475176 scopus 로고    scopus 로고
    • Role of p12(CDK2-AP1) in transforming growth factor-beta1-mediated growth suppression
    • Hu MG, Hu GF, Kim Y, Tsuji T, McBride J, et al. (2004) Role of p12(CDK2-AP1) in transforming growth factor-beta1-mediated growth suppression. Cancer Res 64: 490-499.
    • (2004) Cancer Res , vol.64 , pp. 490-499
    • Hu, M.G.1    Hu, G.F.2    Kim, Y.3    Tsuji, T.4    McBride, J.5
  • 10
    • 18844365357 scopus 로고    scopus 로고
    • p12CDK2-AP1 gene therapy strategy inhibits tumor growth in an in vivo mouse model of head and neck cancer
    • Figueiredo ML, Kim Y, St John MA, Wong DT (2005) p12CDK2-AP1 gene therapy strategy inhibits tumor growth in an in vivo mouse model of head and neck cancer. Clin Cancer Res 11: 3939-3948.
    • (2005) Clin Cancer Res , vol.11 , pp. 3939-3948
    • Figueiredo, M.L.1    Kim, Y.2    St John, M.A.3    Wong, D.T.4
  • 11
    • 33845595885 scopus 로고    scopus 로고
    • Loss of p12CDK2-AP1 expression in human oral squamous cell carcinoma with disrupted transforming growth factor-beta-Smad signaling pathway
    • Peng H, Shintani S, Kim Y, Wong DT (2006) Loss of p12CDK2-AP1 expression in human oral squamous cell carcinoma with disrupted transforming growth factor-beta-Smad signaling pathway. Neoplasia 8: 1028-1036.
    • (2006) Neoplasia , vol.8 , pp. 1028-1036
    • Peng, H.1    Shintani, S.2    Kim, Y.3    Wong, D.T.4
  • 12
    • 33745603039 scopus 로고    scopus 로고
    • Expression of cell-cycle regulator CDK2-associating protein 1 (p12CDK2AP1) in transgenic mice induces testicular and ovarian atrophy in vivo
    • Figueiredo ML, Dayan S, Kim Y, McBride J, Kupper TS, et al. (2006) Expression of cell-cycle regulator CDK2-associating protein 1 (p12CDK2AP1) in transgenic mice induces testicular and ovarian atrophy in vivo. Mol Reprod Dev 73: 987-997.
    • (2006) Mol Reprod Dev , vol.73 , pp. 987-997
    • Figueiredo, M.L.1    Dayan, S.2    Kim, Y.3    McBride, J.4    Kupper, T.S.5
  • 15
    • 22044442391 scopus 로고    scopus 로고
    • Expression patterns of mitotic and meiotic cell cycle regulators in testicular cancer and development
    • Diederichs S, Baumer N, Schultz N, Hamra FK, Schrader MG, et al. (2005) Expression patterns of mitotic and meiotic cell cycle regulators in testicular cancer and development. Int J Cancer 116: 207-217.
    • (2005) Int J Cancer , vol.116 , pp. 207-217
    • Diederichs, S.1    Baumer, N.2    Schultz, N.3    Hamra, F.K.4    Schrader, M.G.5
  • 16
    • 0037376711 scopus 로고    scopus 로고
    • Identification of estrogen-regulated genes in the mouse uterus using a delayed-implantation model
    • Lee S, Lee SA, Shim C, Khang I, Lee KA, et al. (2003) Identification of estrogen-regulated genes in the mouse uterus using a delayed-implantation model. Mol Reprod Dev 64: 405-413.
    • (2003) Mol Reprod Dev , vol.64 , pp. 405-413
    • Lee, S.1    Lee, S.A.2    Shim, C.3    Khang, I.4    Lee, K.A.5
  • 17
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E, Bestor TH, Jaenisch R (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69: 915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 18
    • 0032433267 scopus 로고    scopus 로고
    • Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene
    • LeCouter JE, Kablar B, Whyte PF, Ying C, Rudnicki MA (1998) Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene. Development 125: 4669-4679.
    • (1998) Development , vol.125 , pp. 4669-4679
    • LeCouter, J.E.1    Kablar, B.2    Whyte, P.F.3    Ying, C.4    Rudnicki, M.A.5
  • 19
    • 0034702303 scopus 로고    scopus 로고
    • Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1
    • Huppert SS, Le A, Schroeter EH, Mumm JS, Saxena MT, et al. (2000) Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1. Nature 405: 966-970.
    • (2000) Nature , vol.405 , pp. 966-970
    • Huppert1    SS, L.A.2    Schroeter, E.H.3    Mumm, J.S.4    Saxena, M.T.5
  • 20
    • 0036120654 scopus 로고    scopus 로고
    • Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality
    • Biniszkiewicz D, Gribnau J, Ramsahoye B, Gaudet F, Eggan K, et al. (2002) Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality. Mol Cell Biol 22: 2124-2135.
    • (2002) Mol Cell Biol , vol.22 , pp. 2124-2135
    • Biniszkiewicz, D.1    Gribnau, J.2    Ramsahoye, B.3    Gaudet, F.4    Eggan, K.5
  • 21
    • 2942619075 scopus 로고    scopus 로고
    • Deletion of the mouse P450c17 gene causes early embryonic lethality
    • Bair SR, Mellon SH (2004) Deletion of the mouse P450c17 gene causes early embryonic lethality. Mol Cell Biol 24: 5383-5390.
    • (2004) Mol Cell Biol , vol.24 , pp. 5383-5390
    • Bair, S.R.1    Mellon, S.H.2
  • 22
    • 0032851221 scopus 로고    scopus 로고
    • Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E
    • Dealy MJ, Nguyen KV, Lo J, Gstaiger M, Krek W, et al. (1999) Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E. Nat Genet 23: 245-248.
    • (1999) Nat Genet , vol.23 , pp. 245-248
    • Dealy, M.J.1    Nguyen, K.V.2    Lo, J.3    Gstaiger, M.4    Krek, W.5
  • 23
    • 0034177408 scopus 로고    scopus 로고
    • Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice
    • de Klein A, Muijtjens M, van Os R, Verhoeven Y, Smit B, et al. (2000) Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice. Curr Biol 10: 479-482.
    • (2000) Curr Biol , vol.10 , pp. 479-482
    • de Klein, A.1    Muijtjens, M.2    van Os, R.3    Verhoeven, Y.4    Smit, B.5
  • 24
    • 0037315673 scopus 로고    scopus 로고
    • Disruption of the pelota gene causes early embryonic lethality and defects in cell cycle progression
    • Adham IM, Sallam MA, Steding G, Korabiowska M, Brinck U, et al. (2003) Disruption of the pelota gene causes early embryonic lethality and defects in cell cycle progression. Mol Cell Biol 23: 1470-1476.
    • (2003) Mol Cell Biol , vol.23 , pp. 1470-1476
    • Adham, I.M.1    Sallam, M.A.2    Steding, G.3    Korabiowska, M.4    Brinck, U.5
  • 25
    • 17644375501 scopus 로고    scopus 로고
    • Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency
    • Chen PL, Liu F, Cai S, Lin X, Li A, et al. (2005) Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency. Mol Cell Biol 25: 3535-3542.
    • (2005) Mol Cell Biol , vol.25 , pp. 3535-3542
    • Chen, P.L.1    Liu, F.2    Cai, S.3    Lin, X.4    Li, A.5
  • 26
    • 0030034110 scopus 로고    scopus 로고
    • Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells
    • Savatier P, Lapillonne H, van Grunsven LA, Rudkin BB, Samarut J (1996) Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells. Oncogene 12: 309-322.
    • (1996) Oncogene , vol.12 , pp. 309-322
    • Savatier, P.1    Lapillonne, H.2    van Grunsven, L.A.3    Rudkin, B.B.4    Samarut, J.5
  • 27
    • 0028157458 scopus 로고
    • Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts
    • Savatier P, Huang S, Szekely L, Wiman KG, Samarut J (1994) Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts. Oncogene 9: 809-818.
    • (1994) Oncogene , vol.9 , pp. 809-818
    • Savatier, P.1    Huang, S.2    Szekely, L.3    Wiman, K.G.4    Samarut, J.5
  • 28
    • 16344375767 scopus 로고    scopus 로고
    • Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation
    • White J, Stead E, Faast R, Conn S, Cartwright P, et al. (2005) Developmental activation of the Rb-E2F pathway and establishment of cell cycle-regulated cyclin-dependent kinase activity during embryonic stem cell differentiation. Mol Biol Cell 16: 2018-2027.
    • (2005) Mol Biol Cell , vol.16 , pp. 2018-2027
    • White, J.1    Stead, E.2    Faast, R.3    Conn, S.4    Cartwright, P.5
  • 30
    • 0034530165 scopus 로고    scopus 로고
    • Targeted mutations of transforming growth factor-beta genes reveal important roles in mouse development and adult homeostasis
    • Dunker N, Krieglstein K (2000) Targeted mutations of transforming growth factor-beta genes reveal important roles in mouse development and adult homeostasis. Eur J Biochem 267: 6982-6988.
    • (2000) Eur J Biochem , vol.267 , pp. 6982-6988
    • Dunker, N.1    Krieglstein, K.2
  • 31
    • 0034023371 scopus 로고    scopus 로고
    • Functions of mammalian Smad genes as revealed by targeted gene disruption in mice
    • Weinstein M, Yang X, Deng C (2000) Functions of mammalian Smad genes as revealed by targeted gene disruption in mice. Cytokine Growth Factor Rev 11: 49-58.
    • (2000) Cytokine Growth Factor Rev , vol.11 , pp. 49-58
    • Weinstein, M.1    Yang, X.2    Deng, C.3
  • 32
    • 13644270443 scopus 로고    scopus 로고
    • Recent advances in understanding transforming growth factor beta regulation of orofacial development
    • Greene RM, Pisano MM (2005) Recent advances in understanding transforming growth factor beta regulation of orofacial development. Hum Exp Toxicol 24: 1-12.
    • (2005) Hum Exp Toxicol , vol.24 , pp. 1-12
    • Greene, R.M.1    Pisano, M.M.2
  • 33
    • 24644439599 scopus 로고    scopus 로고
    • Tgf-beta superfamily and mouse craniofacial development: Interplay of morphogenetic proteins and receptor signaling controls normal formation of the face
    • Dudas M, Kaartinen V (2005) Tgf-beta superfamily and mouse craniofacial development: interplay of morphogenetic proteins and receptor signaling controls normal formation of the face. Curr Top Dev Biol 66: 65-133.
    • (2005) Curr Top Dev Biol , vol.66 , pp. 65-133
    • Dudas, M.1    Kaartinen, V.2
  • 35
    • 0020467073 scopus 로고
    • The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
    • Moll R, Franke WW, Schiller DL, Geiger B, Krepler R (1982) The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31: 11-24.
    • (1982) Cell , vol.31 , pp. 11-24
    • Moll, R.1    Franke, W.W.2    Schiller, D.L.3    Geiger, B.4    Krepler, R.5
  • 36
    • 16744366073 scopus 로고    scopus 로고
    • Composition, regulation, and function of the cytoskeleton in mammalian eggs and embryos
    • Gallicano GI (2001) Composition, regulation, and function of the cytoskeleton in mammalian eggs and embryos. Front Biosci 6: D1089-1108.
    • (2001) Front Biosci , vol.6
    • Gallicano, G.I.1
  • 37
    • 2342471358 scopus 로고    scopus 로고
    • Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein
    • Hafner M, Wenk J, Nenci A, Pasparakis M, Scharffetter-Kochanek K, et al. (2004) Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein. Genesis 38: 176-181.
    • (2004) Genesis , vol.38 , pp. 176-181
    • Hafner, M.1    Wenk, J.2    Nenci, A.3    Pasparakis, M.4    Scharffetter-Kochanek, K.5
  • 39
    • 1242316243 scopus 로고    scopus 로고
    • Morpho-regulation of ectodermal organs: Integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway
    • Plikus M, Wang WP, Liu J, Wang X, Jiang TX, et al. (2004) Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway. Am J Pathol 164: 1099-1114.
    • (2004) Am J Pathol , vol.164 , pp. 1099-1114
    • Plikus, M.1    Wang, W.P.2    Liu, J.3    Wang, X.4    Jiang, T.X.5
  • 40
    • 2942582215 scopus 로고    scopus 로고
    • A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination
    • Ramirez A, Page A, Gandarillas A, Zanet J, Pibre S, et al. (2004) A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination. Genesis 39: 52-57.
    • (2004) Genesis , vol.39 , pp. 52-57
    • Ramirez, A.1    Page, A.2    Gandarillas, A.3    Zanet, J.4    Pibre, S.5
  • 41
    • 0029553183 scopus 로고
    • An overview of epithelio-mesenchymal transformation
    • Hay ED (1995) An overview of epithelio-mesenchymal transformation. Acta Anat (Basel) 154: 8-20.
    • (1995) Acta Anat (Basel) , vol.154 , pp. 8-20
    • Hay, E.D.1
  • 42
    • 24644487312 scopus 로고    scopus 로고
    • TGF-beta and epithelial-to-mesenchymal transitions
    • Zavadil J, Bottinger EP (2005) TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 24: 5764-5774.
    • (2005) Oncogene , vol.24 , pp. 5764-5774
    • Zavadil, J.1    Bottinger, E.P.2
  • 43
    • 0032080835 scopus 로고    scopus 로고
    • Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease
    • Mizuno S, Kurosawa T, Matsumoto K, Mizuno-Horikawa Y, Okamoto M, et al. (1998) Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease. J Clin Invest 101: 1827-1834.
    • (1998) J Clin Invest , vol.101 , pp. 1827-1834
    • Mizuno, S.1    Kurosawa, T.2    Matsumoto, K.3    Mizuno-Horikawa, Y.4    Okamoto, M.5
  • 44
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, et al. (2003) BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 9: 964-968.
    • (2003) Nat Med , vol.9 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3    Mammoto, T.4    Charytan, D.5
  • 45
    • 14844364701 scopus 로고    scopus 로고
    • Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity
    • Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, et al. (2005) Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science 307: 1603-1609.
    • (2005) Science , vol.307 , pp. 1603-1609
    • Ozdamar, B.1    Bose, R.2    Barrios-Rodiles, M.3    Wang, H.R.4    Zhang, Y.5


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