CAMP-responsive element modulator α (CREMα) trans-represses the transmembrane glycoprotein CD8 and contributes to the generation of CD3 +CD4-CD8- T cells in health and disease

Journal of Biological Chemistry

Volumn 288, Issue 44, 2013, Pages 31880-31887

  Hedrich, Christian M ^a,b   Rauen, Thomas ^a,c   Crispin, Jose C ^a   Koga, Tomohiro ^a   Ioannidis, Christina ^a   Zajdel, Melissa ^a   Kyttaris, Vasileios C ^a   Tsokos, George C ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE NEGATIVES; MOLECULAR MECHANISM; PERIPHERAL BLOOD; PRO-INFLAMMATORY CYTOKINES; REGULATORY ELEMENTS; SYSTEMIC LUPUS ERYTHEMATOSUS; TRANSCRIPTIONAL SILENCING; TRANSMEMBRANE GLYCOPROTEINS;

CELL MEMBRANES; CYTOLOGY;

T-CELLS;

CD8 ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT MODULATOR; CYCLIC AMP RESPONSIVE ELEMENT MODULATOR ALPHA; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CASE REPORT; CD3+ CD4- CD8- T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CD8A GENE; CD8B GENE; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; GENE; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE;

AUTOIMMUNE DISEASES; CD8; CELL DIFFERENTIATION; CELLULAR IMMUNE RESPONSE; CREMΑ; DOUBLE-NEGATIVE T CELLS; GENE REGULATION; SLE; T CELL;

ANTIGENS, CD3; ANTIGENS, CD4; ANTIGENS, CD8; CD8-POSITIVE T-LYMPHOCYTES; CYCLIC AMP RESPONSE ELEMENT MODULATOR; FEMALE; GENE SILENCING; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; REPRESSOR PROTEINS; RESPONSE ELEMENTS; TRANSCRIPTION, GENETIC;

EID: 84887125401     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.508655     Document Type: Article

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